Detalhe da pesquisa
1.
Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts.
Science
; 214(4525): 1137-9, 1981 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-6795718
2.
Identification of 6-azauridine triphosphate in L1210 cells and its possible relevance to cytotoxicity.
Cancer Res
; 49(2): 289-94, 1989 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-2463073
3.
Study of the cytotoxicity and metabolism of 4-amino-3-carboxamido-1-(beta-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine using inhibitors of adenosine kinase and adenosine deaminase.
Cancer Res
; 39(8): 3018-23, 1979 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-222442
4.
Cytotoxicity of a new uridine analog, 4-hydroxy-1-(beta-D-ribofuranosyl)-pyridazine-6-one, and its interaction with uridine kinase.
Cancer Res
; 42(1): 100-6, 1982 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-6172193
5.
Effects of the tricyclic nucleoside 6-amino-4-methyl-8-(beta-D-ribofuranosyl)- pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine on the viability and cell cycle distribution of L1210 cells in vitro.
Cancer Res
; 45(12 Pt 1): 6355-61, 1985 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-4063986
6.
Potentiation of 2'-deoxyguanosine cytotoxicity by a novel inhibitor of purine nucleoside phosphorylase, 8-amino-9-benzylguanine.
Cancer Res
; 46(2): 519-23, 1986 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-3079664
7.
Dual mechanisms of inhibition of DNA synthesis by triciribine.
Cancer Res
; 50(16): 4891-9, 1990 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-2379153
8.
Conformation of pyridazine nucleosides: the molecular structure of 4-hydroxy-1-(beta-D-ribofuranosyl)pyridazin-6-one (3-deaza-6-azauridine).
Biochim Biophys Acta
; 520(1): 229-32, 1978 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-698230
9.
A rapid and sensitive screening method for the detection of anti-2-acetylaminofluorene immunoglobulins.
J Immunol Methods
; 109(1): 103-12, 1988 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-3356906
10.
Synthesis and antileukemic activities of furanyl, pyranyl, and ribosyl derivatives of 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide and 3-(3,3-dimethyl-1-triazeno)pyrazole-4-carboxamide.
J Med Chem
; 22(11): 1422-5, 1979 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-533891
11.
Pyrrolopyrimidine nucleosides. 18. Synthesis and chemotherapeutic activity of 4-amino-7-(3-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (3'-deoxysangivamycin) and 4-amino-7-(2-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (2'-deoxysangivamycin).
J Med Chem
; 26(1): 25-9, 1983 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-6827526
12.
Design, synthesis, and antiviral evaluation of 2-substituted 4,5-dichloro- and 4,6-dichloro-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections.
J Med Chem
; 40(5): 802-10, 1997 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-9057867
13.
Design, synthesis, and antiviral evaluation of 2-chloro-5,6-dihalo-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections.
J Med Chem
; 40(5): 811-8, 1997 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-9057868
14.
Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides.
J Med Chem
; 43(12): 2430-7, 2000 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-10882370
15.
Synthesis and antiviral evaluation of trisubstituted indole N-nucleosides as analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB).
J Med Chem
; 43(12): 2449-56, 2000 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-10882372
16.
Synthesis and antiviral evaluation of certain disubstituted benzimidazole ribonucleosides.
J Med Chem
; 39(18): 3477-82, 1996 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-8784445
17.
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine.
J Med Chem
; 25(7): 813-21, 1982 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-7108897
18.
Structure-activity relationships among 2-substituted 5,6-dichloro-, 4,6-dichloro-, and 4,5-dichloro-1-[(2-hydroxyethoxy) methyl]- and -1-[(1,3-dihydroxy-2-propoxy) methyl]benzimidazoles.
J Med Chem
; 39(4): 881-91, 1996 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-8632412
19.
Synthesis and cytotoxicity studies of 8-amino-6-methyl-2-beta-D-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthyle ne (7-aza-TCN) and the corresponding 2'-deoxy- and arabinonucleoside analogues.
J Med Chem
; 33(12): 3170-6, 1990 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-2258902
20.
Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability.
J Med Chem
; 43(12): 2473-8, 2000 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-10882375