Detalhe da pesquisa
1.
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nat Immunol
; 20(4): 458-470, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890796
2.
Mechanisms underlying DMARD inefficacy in difficult-to-treat rheumatoid arthritis: a narrative review with systematic literature search.
Rheumatology (Oxford)
; 61(9): 3552-3566, 2022 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238332
3.
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).
Ann Rheum Dis
; 78(12): 1642-1652, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582377
4.
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.
Ann Rheum Dis
; 78(6): 761-772, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30878974
5.
A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE).
Ann Rheum Dis
; 75(1): 196-202, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26038091
6.
Stratified medicine in inflammatory disorders: From theory to practice.
Clin Immunol
; 161(1): 11-22, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934386
7.
Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Buch et al.
Ann Rheum Dis
; 79(11): e141, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31302598
8.
Anti-vimentin antibodies: a unique antibody class associated with therapy-resistant lupus nephritis.
Lupus
; 29(6): 569-577, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32216516
9.
Recent developments in the transcriptional regulation of cytolytic effector cells.
Nat Rev Immunol
; 4(11): 900-11, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15516969
10.
B-cell targeted therapies in human autoimmune diseases: an updated perspective.
Immunol Rev
; 237(1): 264-83, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20727041
11.
An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Cell Rep Med
; 4(8): 101130, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490914
12.
A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration.
Cell Genom
; 3(6): 100302, 2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37388919
13.
Pretreatment synovial transcriptional profile is associated with early and late clinical response in rheumatoid arthritis patients treated with rituximab.
Ann Rheum Dis
; 71(11): 1888-94, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22736099
14.
Association of endogenous anti-interferon-α autoantibodies with decreased interferon-pathway and disease activity in patients with systemic lupus erythematosus.
Arthritis Rheum
; 63(8): 2407-15, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21506093
15.
Inflammation and autoantibody markers identify rheumatoid arthritis patients with enhanced clinical benefit following rituximab treatment.
Arthritis Rheum
; 63(12): 3681-91, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22127691
16.
Distal regions of the human IFNG locus direct cell type-specific expression.
J Immunol
; 185(3): 1492-501, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20574006
17.
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes.
Proc Natl Acad Sci U S A
; 106(42): 17876-81, 2009 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19805038
18.
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.
J Med Chem
; 65(21): 14721-14739, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279149
19.
Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus.
J Exp Med
; 218(7)2021 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019642
20.
Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial.
Arthritis Rheumatol
; 73(10): 1835-1846, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34042314