Risk factors for additional surgery after closed reduction of hip developmental dislocation.

PURPOSE: to evaluate the risk factors for additional surgery after closed reduction of hip developmental dislocation Methods : closed reduction for developmental hip dislocation was performed on 72 patients, with a total of 82 hips (10 bilateral). Were included only patients with irreducible hip dislocation who were treated by overhead traction followed by closed reduction under general anaesthesia and spica casting. The mean age at the time of closed reduction was 10 months, with 82% of dislocation diagnosed after the age of 6 months. In 28 hips (34.1%), no additional surgical procedure was necessary, while 54 hips (65.9%) needed an additional surgery, consisting in Salter osteotomy in 40 hips (48.8%) or open hip reduction in 14 (17.1%). RESULTS: risk factors for the need of additional surgery were: older age at the time of reduction, male sex, high grade of hip dislocation (Tönnis grade 3 and 4, versus grade 1 and 2), and quality of hip reduction. All the patients older than 17 months at the time of closed reduction needed additional surgery. Bilateral hip dislocation had poorer Severin grading than unilateral dislocation. Poorer Kalamchi scoring was associated with older age and with the presence of the cephalic nucleus at the time of reduction. CONCLUSION: this study confirmed delayed diagnosis of hip dislocation leads to a more extensive treatment with poorer issue.

[Spermiological Study Of Patients Treated For Infertility At The Medical Biology Laboratory Of Sikasso Hospital]. / Etude Spermiologique Chez Les Patients Suivis Pour Infertilite Au Laboratoire De Biologie Medicale De l'Hopital De Sikasso.

AIM: The aim of this study was to establish the spermiological profile of patients treated for infertility at Sikasso Hospital. MATERIAL AND METHODS: This was a prospective descriptive cross-sectional study, which took place from January to December 2022 at Sikasso Hospital. Interpretation of spermiological parameters was based on standards established by the World Health Organization in 2010. RESULTS: We enrolled 41 patients, 51.22% of whom had disturbed spermiological parameters. The abnormalities were azoospermia (21.92%), asthenooligozoospermia (12.20%), asthenozoospermia (7.32%), oligozoospermia (7.32%) and asthenonecrozoospermia (2.44%). These anomalies were mainly observed in the 34-44 age group (47.62%). CONCLUSION: This study revealed significant disturbances in spermiological parameters, with azoospermia being the most frequent abnormality.

BUT: L'objectif de cette étude était d'établir le profil spermiologique des patients suivis pour infertilité à l'hôpital de Sikasso. MATÉRIEL ET MÉTHODES: Il s'agissait d'une étude transversale prospective descriptive, qui s'est déroulée de janvier à décembre 2022 à l'hôpital de Sikasso. L'interprétation des paramètres spermiologique a fait recours aux normes établies par l'Organisation mondiale de la santé en 2010. RESULTATS: Nous avons colligé 41 patients dont 51,22% avaient ses paramètres spermiologiques perturbés. Les anomalies étaient l'azoospermie (21,92%), l'asthénooligozoospermie (12,20%), l'asthénozoospermie (7,32%), l'oligozoospermie (7,32 %) et l'asthénonécrozoospermie (2,44 %). Ces anomalies étaient observées majoritairement dans la tranche d'âge 34-44 ans avec 47,62%. CONCLUSION: cette étude a révélé des perturbations importantes des paramètres spermiologiques et l'azoospermie a constitué l'anomalie la plus fréquente.

[Anatomical and functional results of total hip prosthesesat Kati University Hospital]. / Résultats anatomiques et Fonctionnels des prothèses totales de hanche au CHU de Kati.

INTRODUCTION: Hip prosthetic surgery is a commonly performed procedure in orthopedic trauma. It has changed the prognosis of traumatic, degenerative and inflammatory hip diseases. OBJECTIVE: The aim of this work was to evaluate the functional and anatomical results of a series of total hip replacements in our department in the short and medium term and to compare them with the literature. PATIENTS AND METHODS: This was a retrospective descriptive and analytical study of a series of 96 total hip replacements performed at the University Hospital of Kati, from January 2019 to December 2021. Functional discomfort was assessed in all patients before and after surgery. The prostheses used were of the Aston, AK, Surgival, Evolutus and Sharma types. The anatomical results were assessed by radiological criteria and the functional results by Postel Merle d'Aubigné criteria. RESULTS: In our study, 96 hips were operated on by total prosthesis in 91 patients, including five bilateral cases. The patients were 49 men and 42 women. The average age was 46.9 years. Coxarthrosis associated with necrosis of the femoral head was the most frequent indication for arthroplasty (n=51), followed by femoral neck fracture (n=26). The inclination of the cup was anatomical in 73.3% of cases. The mean femoral offset was 44.1 mm with extremes of 26 and 59 mm. Cup anteversion was normal in 79.4% of cases. The mean preoperative PMA score increased from 5.2 (0 and 15) to 16.9 (4 and 18) late postoperatively. Our results were satisfactory in 89% of cases. CONCLUSION: Total hip arthroplasty allows, in the vast majority of cases, to recover indolence and perfect functionality of the hip.

INTRODUCTION: La chirurgie prothétique de hanche est une intervention couramment pratiquée en orthopédie traumatologie. Elle a changé le pronostic des pathologies traumatiques, dégénératives et inflammatoires de la hanche. OBJECTIF: Le but de ce travail était d'évaluer à court et moyen terme les résultats fonctionnels et anatomiques d'une série de prothèses totales de hanche dans notre service et de les comparer avec la littérature. PATIENTS ET MÉTHODES: Il s'agissait d'une étude rétrospective descriptive et analytique d'une série de 96 prothèses totales de hanche réalisées au CHU de Kati, allant de janvier 2019 à décembre 2021. Les gênes fonctionnelles ont été appréciées chez tous les patients avant et après l'intervention. Les prothèses utilisées étaient de type Aston, AK, Surgival, Evolutus et Sharma. Les résultats anatomiques ont été appréciés par les critères radiologiques et les résultats fonctionnels par les critères de Postel Merle d'Aubigné. RÉSULTATS: Au cours de notre étude 96 hanches ont été opérées par prothèse totale chez 91 patients dont cinq cas bilatéraux. Il s'agit de 49 hommes et 42 femmes. L'âge moyen était 46,9 ans. La coxarthrose associée à la nécrose de la tête fémorale était l'indication de l'arthroplastie la plus fréquente (n=51) suivie de la fracture du col fémoral (n=26). L'inclinaison de la cupule était anatomique dans 73,3% des cas. L'offset fémoral moyen était 44,1 mm avec des extrêmes de 26 et 59 mm. L'antéversion de la cupule était normale dans 79,4% des cas. Le score moyen du PMA préopératoire était passé de 5,2 (0 et 15) à 16,9 (4 et 18) en postopératoire tardive. Nos résultats étaient satisfaisants dans 89% des cas. CONCLUSION: L'arthroplastietotaledehanchepermet,danslatrèsgrandemajoritédescas,deretrouve runeindolenceet une fonctionnalitéparfaite de la hanche.

[Factors Influencing Low Bcg, Var1 And Penta3 Immunization Coverage Among Children Aged 0-23 Months In Mopti Health District In 2021]. / Facteurs Influençant La Faible Couverture Vaccinale En Bcg, En Var1 Et En Penta3 Chez Les Enfants De 0 A 23 Mois Dans Le District Sanitaire De Mopti En 2021.

INTRODUCTION: The health district of Mopti is confronted with factors that influence its vaccination coverage [1]. The aim of the study was to study the factors influencing the low BCG vaccination coverage in VAR1 and Penta3 in children aged 0 to 23 months in the health district in 2021. METHODOLOGY: We carried out a descriptive cross-sectional study, collected information from 280 mothers questioned on the services provided by the vaccination service for children before the age of two, the reasons for incompleteness using a questionnaire. Univariate and multivariate logistic regression analysis was done for the variables using SPSS software. An association was significant when p < 0.05. RESULTS: Vaccination completeness was 53.08%, varying from 94% BCG, 79% VAR1 and 83% Penta3. The analysis showed that mothers who spent more time at the vaccination center (P=0.098, Chi-square=18.617), who missed certain sessions (P=0.174, Chi-square=13.371) and who were informed of missed consumables (P=0.278, Chi-square= 7.485) are significantly associated with vaccine incompleteness. CONCLUSION: Vaccination completeness was insufficient despite good knowledge of the mothers on vaccination.

INTRODUCTION: Le district sanitaire de Mopti est confronté à des facteurs qui influencent sa couverture vaccinale [1]. L'étude avait pour but d'étudier les facteurs influençant la faible couverture vaccinale en BCG en VAR1 et en Penta3 chez les enfants de 0 à 23 mois dans le district sanitaire en 2021. MÉTHODOLOGIE: Nous avons réalisé une étude transversale descriptive, colligé les informations de 280 mères interrogées sur les prestations du service de vaccination de l'enfant avant l'âge de deux ans, les raisons d'incomplétude à l'aide d'un questionnaire. Une analyse de régression logistique univariée et multivariée a été faite pour les variables en utilisant le logiciel SPSS. Une association était significative lorsque p < 0,05. RÉSULTATS: La complétude vaccinale était de 53,08%, variant de 94% BCG, 79% VAR1 et 83% Penta3. L'analyse a montré que les mères qui passaient plus de temps au centre de vaccination (P=0,098, Khi-carré= 18,617), qui manquaient certaines séances (P=0,174, Khi-carré= 13,371) et qui étaient informées de manques de consommables (P=0,278, Khi-carré= 7,485) sont significativement associées à l'incomplétude vaccinale. CONCLUSION: La complétude vaccinale était insuffisante malgré de bonnes connaissances des mères sur vaccination.

Ent-kaurane diterpenoids from the Annonaceae family: a review of research progress and call for further research.

The Annonaceae is one of the plant families with members that are credited with numerous pharmacological functions. Among the group of compounds responsible for these bioactivities are the ent-kaurane diterpenoids. The ent-kauranes are a group of 20-Carbon, tetracyclic diterpenoids that are widely distributed in other plant families including the Annonaceae family. This mini-review focuses mainly on the ent-kaurane diterpenoids isolated from the Annonaceae family, delineates the various biological activities of these compounds, and highlights the research gaps that exist for further scientific scrutiny.

Attraction of Stomoxys sp. to various fruits and flowers in Mali.

The attraction of three Stomoxys species to 26 fruits and 26 flowers of different plant species was investigated in two different sites in Mali during 2008. Stomoxys niger bilineatus Grunberg (Diptera: Muscidae) was attracted to a wider spectrum of species, significantly attracted by four fruits and eight flowers compared with control traps, whereas S. sitiens Rondani (Diptera: Muscidae) was attracted to six fruits and seven flowers of different plants, and S. calcitrans L. (Diptera: Muscidae) was only attracted to one fruit and three flowers. Cold anthrone assays showed a significantly higher prevalence of sugar feeding amongst all three species at the lagoon site than at the site near Mopti. The rhythm of activity study shows temporally separated blood- and sugar-feeding periods for S. niger bilineatus and S. sitiens, but not for S. calcitrans. A comparison between blood and sugar feeding throughout the day shows that sugar feeding activity is as frequent as blood feeding activity. Because not much is known about the preferred sugar sources for Stomoxys species in their natural habitats, the present study provides valuable information regarding the attraction capability of several plants with possible future implication for Stomoxys control strategies.

[Diagnosis and evaluation of the response to treatment of chronic myeloid leukaemia in Mali by fluorescent in situ hybridization]. / Diagnostic et Évaluation de la Réponse Thérapeutique de la Leucémie Myéloïde Chronique au Mali par l'Hybridation in situ Fluorescente.

Objective: Chronic myeloid leukemia (CML) is a hematologic malignancy characterized by the presence of the Philadelphia chromosome or its molecular equivalent, the BCR/ABL1 fusion gene. Diagnosis and monitoring of CML are done by detecting this chromosome, the BCR/ABL1 gene, or the BCR/ABL1 transcript. In Mali, genetic tools of diagnosis and follow-up are still lacking, so we did this study with the objectives of developing the FISH technique to diagnose, to follow up, and to characterize the cytogenetic profile of CML patients. Methods: We carried out FISH technique by using the dual color dual fusion probe for BCR/ABL1 on interphase nuclei and metaphases. Slides were scanned with an epifluorescence microscope. Results: A total of 25 patients (16 for diagnostic and 9 for follow-up) were included. We achieved a 92% success rate for obtaining metaphases. The BCR/ABL1 gene fusion signal was present in 22 patients. Among those 22 patients, 16 presented a typical signal pattern and 6 presented atypical signal patterns. Conclusion: We set up the FISH technique in Mali for the diagnosis and the follow-up of CML patients and identified atypical translocation of t(9;22).

[Anatomical and Junctional results of total hip prosthesesat Kati University Hospital]. / Résultats anatomiques et Fonctionnels des prothèses totales de hanche au CHU de Kati.

INTRODUCTION: Hip prosthetic surgery is a commonly performed procedure in orthopedic trauma. It has changed the prognosis of traumatic, degenerative and inflammatory hip diseases. OBJECTIVE: The aim of this work was to evaluate the functional and anatomical results of a series of total hip replacements in our department in the short and medium term and to compare them with the literature. PATIENTS AND METHODS: This was a retrospective descriptive and analytical study of a series of 96 total hip replacements performed at the University Hospital of Kati, from January 2019 to December 2021. Functional discomfort was assessed in all patients before and after surgery. The prostheses used were of the Aston, AK, Surgival, Evolutus and Sharma types. The anatomical results were assessed by radiological criteria and the functional results by Postel Merle d'Aubigné criteria. RESULTS: In our study, 96 hips were operated on by total prosthesis in 91 patients, including five bilateral cases. The patients were 49 men and 42 women. The average age was 46.9 years. Coxarthrosis associated with necrosis of the femoral head was the most frequent indication for arthroplasty (n=51), followed by femoral neck fracture (n=26). The inclination of the cup was anatomical in 73.3% of cases. The mean femoral offset was 44.1 mm with extremes of 26 and 59 mm. Cup anteversion was normal in 79.4% of cases. The mean preoperative PMA score increased from 5.2 (0 and 15) to 16.9 (4 and 18) late postoperatively. Our results were satisfactory in 89% of cases. CONCLUSION: Total hip arthroplasty allows, in the vast majority of cases, to recover indolence and perfect functionality of the hip.

INTRODUCTION: La chirurgie prothétique de hanche est une intervention couramment pratiquée en orthopédie traumatologie. Elle a changé le pronostic des pathologies traumatiques, dégénératives et inflammatoires de la hanche. OBJECTIF: Le but de ce travail était d'évaluer à court et moyen terme les résultats fonctionnels et anatomiques d'une série de prothèses totales de hanche dans notre service et de les comparer avec la littérature. PATIENTS ET MÉTHODES: Il s'agissait d'une étude rétrospective descriptive et analytique d'une série de 96 prothèses totales de hanche réalisées au CHU de Kati, allant de janvier 2019 à décembre 2021. Les gênes fonctionnelles ont été appréciées chez tous les patients avant et après l'intervention. Les prothèses utilisées étaient de type Aston, AK, Surgival, Evolutus et Sharma. Les résultats anatomiques ont été appréciés par les critères radiologiques et les résultats fonctionnels par les critères de Postel Merle d'Aubigné. RÉSULTATS: Au cours de notre étude 96 hanches ont été opérées par prothèse totale chez 91 patients dont cinq cas bilatéraux. Il s'agit de 49 hommes et 42 femmes. L'âge moyen était 46,9 ans. La coxarthrose associée à la nécrose de la tête fémorale était l'indication de l'arthroplastie la plus fréquente (n=51) suivie de la fracture du col fémoral (n=26). L'inclinaison de la cupule était anatomique dans 73,3% des cas. L'offset fémoral moyen était 44,1 mm avec des extrêmes de 26 et 59 mm. L'antéversion de la cupule était normale dans 79,4% des cas. Le score moyen du PMA préopératoire était passé de 5,2 (0 et 15) à 16,9 (4 et 18) en postopératoire tardive. Nos résultats étaient satisfaisants dans 89% des cas. CONCLUSION: L'arthroplastietotaledehanchepermet,danslatrèsgrandemajoritédescas,deretrouve runeindolenceet une fonctionnalitéparfaite de la hanche.

Clinical, paraclinical and genetic aspects of autosomal recessive cerebellar ataxias (ARCA) in Mali.

Introduction: Autosomal recessive cerebellar ataxias (ARCA) are a group of rare and heterogynous neurodegenerative diseases mainly characterized by unbalance and walking difficulty and movement incoordination. Objectives: To clinically and paraclinically characterize ARCA in the department of Neurology at the Teaching Hospital of Point G and identify the underlying genetic defect. Patients and method: We have conducted a longitudinal and prospective study from January 2018 to December 2020. Patients with ARCA phenotype seen in the Department of Neurology at the Teaching Hospital of Point "G" were enrolled. Results: We have enrolled 7 families totaling 13 patients after giving an informed verbal and written consent. The sex ratio was 2.2 in favor of males, Kayes region and Fulani ethnic group were respectively the most represented region and ethnic group.Walking difficulty represented the major symptom followed by loss of vibration and joint sense, nystagmus, dysarthria and skeletal deformities. Alpha-foetoprotein level was high in one patient. Genetic testing confirmed Friedreich ataxia in one family and was not conclusive in 4 families. Conclusion: This study showed that ARCA are not uncommon in Mali and genetic testing is crucial to confirm the diagnosis.

Introduction: Les ataxies cérébelleuses autosomiques récessives (ACAR) constituent un groupe de maladies neurodégénératives rares et hétérogènes caractérisées essentiellement par un trouble de l'équilibre et de la marche, et un trouble de la coordination des mouvements. Objectifs: Caractériser les signes cliniques, paracliniques et génétiques des ataxies cérébelleuses autosomiques récessives au Service de Neurologie du CHU du Point "G". Patients et méthodes: Nous avons réalisé une étude de cas enrôlé dans le cadre d'une étude longitudinale et prospective allant de Janvier 2018 à Décembre 2020, portant sur des patients présentant des symptômes d'ACAR et ayant donné leur consentement éclairé. Résultats: Nous avons enrôlé sept familles totalisant 13 patients. Le sexe ratio était de 2,2 en faveur des hommes, la région de Kayes était la plus représentée et l'ethnie peulh était majoritaire. Les troubles de la marche ont représenté les signes majeurs suivis de troubles de la sensibilité profonde, de nystagmus, de dysarthrie, et des déformations ostéoarticulaires. L'alpha-foetoprotéine était élevée chez une patiente. Le test génétique a retrouvé l'ataxie de Friedreich dans une famille et n'a pas été concluant dans quatre autres. Conclusion: Cette étude montre que les ACAR ne sont pas rares au Mali et l'exploration génétique constitue un outil indispensable pour leur diagnostic de certitude.

[Hysterectomy: indications and advantages of the vaginal route in Mali]. / Hystérectomie: indications et avantages de la voie vaginale au Mali.

The purpose of this report was to determine the frequency of hysterectomy and describe its indications and outcomes. A retrospective, descriptive study related to active hysterectomy of was conducted at the reference health centre of commune V in Bamako, Mali from January 1st, 2004 to December 31st, 2008. All hysterectomy patients with complete medical files were included. A total of 172 files were identified including 152 that were complete. Hysterectomy accounted for 1.38% of all interventions during the study period. The procedure was carried out in emergency in 0.14% and electively in 13.39%. Mean patient age was 47.9 +/- 11.7 years; 89 patients were older than 45 years. The indications for hysterectomy were complicated uterine fibroids in 82 patients, genital prolapse in 44, adenomyosis in 10, obstetrical hysterectomy in 13 and cervical dysplasia in 3. The abdominal route was used in 100 patients (65.8%) and the vaginal rout in 52 (34.2%). The duration of the procedure and hospital stay was longer after hysterectomy by the abdominal (p<0.05). Perioperative complications were observed in 17% of patients after abdominal hysterectomy versus 7.69% after vaginal hysterectomy. Two maternal deaths due to hemorrhagic shock were observed after obstetrical hysterectomy. Hysterectomy is a frequent intervention that is not without complication risks. Choice of route depends on the indication and skill of the operator. Although endoscopic surgery is still difficult to perform in developing countries, development of vaginal hysterectomy is necessary to reduce perioperative complications.

[Comparison of the performance of viral load screening from plasma and from the oneblotting paper (Oudried Blood Spot), protocol in people living with the human immunodeficiency virus (PLHIV) in Bamako]. / Comparaison des valeurs de charges virales realisees sur plasma et sur goutte de sang seche Oudried Blood Spot(DBS) chez les personnes vivant avec levirus de l'immunodeficience humaine (VIH) a Bamako.

INTRODUCTION: The use of blotting paper as a support for quantification of viral load could improve the virological monitoring of patients on Human Immunodeficiency Virus treatment in Mali. The urgency is obvious to us that the coverage in charge is only 10% for the achievement of the 3rd 90. OBJECTIVE: To assess the performance of viral load screening (sensitivity, specificity, concordance) of DBS from the one spot DBS protocol according to plasma in people living with the human immunodeficiency virus (PLHIV) in Bamako. METHODS: A total of 130 blotting papers were made from blood samples received from five sites for monitoring live persons with HIV. These blotting papers thus made were analyzed with the Abbott m2000 apparatus for the purpose of quantifying the viral load with plasma as reference sample. The extraction was done with the m2000SP automatic extractor, following the protocol 1.0 mL HIV-RNA DBS Protocol for paper. Furthermore, the extraction of plasma RNA on the m2000SP was done according to the 0.6 mL HIV-1 RNA protocol. RESULTS: With 130 samples with detectable viral loads, we obtained a correlation of r = 0.837 (p <0.001). In addition, the average difference between the viral load on blotting paper and plasma was 0.512 log / virological copies with a kappa coefficient = 0.708. The threshold of 1000 copies / mL defined as virological success in our study allowed us to obtain a sensitivity of 87% and a specificity of 100%. CONCLUSION: Decentralized zones or virological plasma monitoring is not accessible, the new Protocol one spot of Abbott laboratory offers an interesting opportunity for the follow-up of these patients with good performance at the threshold of 1000 copies. The use of DBS as a virological support can contribute effectively to the achievement of the 3rd 90.

INTRODUCTION: L'utilisation du papier buvard comme support de quantification de la charge virale pourrait améliorer le suivi virologique des patients sous traitement antirétroviral (ARV) au Mali. L'urgence s'impose à nous vula couverture en charge faible(10%) pour l'atteinte du 3ème 90. OBJECTIF: Evaluer les performances de dépistage de la charge virale (sensibilité, spécificité, concordance) des DBS issus du protocole one spot DBS en fonction du plasma chez les personnes vivant avec le virus de l'immunodéficience humaine (PVVIH) à Bamako. MÉTHODES: Au total, 130 papiers buvards ont été confectionnés à partir d'échantillons sanguin reçus de cinq sites de suivi des personnes vivant avec le virus de l'immunodéficience humaine. Ces papiers buvards ainsi confectionnés ont été analysés avec l'appareil Abbott m2000 en vue de la quantification de la charge virale avec comme échantillon de référence le plasma. L'extraction a été faite avec l'extracteur automatique m2000SP, suivant le protocole 1.0 mL HIV-RNA DBS Protocol pour le papier buvard. Par ailleurs, l'extraction de l'acideribonucléique (ARN) plasmatique sur le m2000SP a été faite selon le protocole 0.6 mL HIV-1 RNA. RÉSULTATS: Avec les 130 échantillons avec des charges virales détectables, nous avons obtenu une corrélation de r= 0.837(p<0,001). Par ailleurs, la différence moyenne entre la charge virale sur papier buvard et sur plasma était de 0,512 log/copies virologique avec un coefficient kappa= 0,708. Le seuil de 1000 copies/mL défini comme succès virologique dans notre étude nous a permis d'obtenir une sensibilité de 100% et une spécificité de 87%. CONCLUSION: Dans les zones décentralisées où le suivi virologique sur plasma n'est pas accessible, le nouveau Protocol one spot du laboratoire Abbott offre une opportunité intéressante pour le suivi de ces patients avec de bonne performance au seuil des 1000 copies. Aussi, l'utilisation du DBS comme support virologique peut contribuer efficacement à l'atteinte du 3ème 90.

[Management of chronic osteomyilitis of limbs at kati teaching hospital]. / Prise en charge des osteomyelites chroniques des membres au chu de kati.

OBJECTIVES: the purpose of this work was to describe the epidemiological, clinical, paraclinical and therapeutic aspect of surgical treatment of chronic osteomyilitis of limbs. PATIENTS METHODS: it was a retrospective study over a period of 12 years, from January 2003 to December 2014. It covered all cases of chronic osteomyelitis osteonecrosis treated our service. RESULTS: The authors report the results of the surgical treatment of a series 56 patients operated on for chronic limb osteomyelitis. The mean age was 20.7 years with extremes of 6 months and 56 years. The tibia and femur were the most affected segments. Staphylococcus aureus was the most frequently found germ, 80% of the cases. We obtained complete healing with total cure in 68% of cases and recurrence of suppuration in 32% of cases. CONCLUSION: Chronic osteomyelitis of limbs is a frequent pathology in Africa. Staphylococcus aureus was the most frequently found germ. Surgery in a time seems a good alternative. The rate of recurrence of the suppuration remains high.

OBJECTIF: Le but de ce travail était de présenter les aspects épidémiologiques, cliniques, bactériologiques, radiologiques et thérapeutiques des ostéomyélites chroniques des membres. MÉTHODES: Nous avons réalisé une étude rétrospective sur une période de 12 ans allant de Janvier 2003 à décembre 2014. Elle a porté sur tous les cas d'ostéomyélites chroniques pris en charge chirurgicalement dans notre service. RÉSULTATS: Nous avons recensé 56 cas d'ostéomyélite chronique des membres. L'âge moyen était de 20 ans avec des extrêmes de 6 mois et 56 ans. Le sex-ratio était de 1,9. Le tibia et le fémur ont été les os les plus atteints. Staphylococcus aureus a été le germe le plus fréquent soit 80% des cas. Nous avons obtenu la cicatrisation parfaite de la plaie dans 68% des cas et la récidive de la suppuration dans 32% des cas. CONCLUSION: L'ostéomyélite chronique des membres est une pathologie fréquente en Afrique. Staphyloccocus aureus demeure le germe le plus fréquent. La chirurgie en un temps nous paraît une bonne alternative. Le taux de récidive de la suppuration reste élevé.

[Prevalence of Diabetes and Diabetes-Related Cardiovascular Risk Factors in a Rural Population in Burkina Faso]. / Prévalence du Diabète et Facteurs de Risque Cardiovasculaire Associés dans une Population Rurale au Burkina Faso.

Objective: Rural areas are currently facing lifestyle changes which greatly contribute to an increase in the prevalence of diabetes and cardiovascular diseases. The aim of this study was to estimate the prevalence of Diabetes and Diabetes-related cardiovascular diseases in a rural population in Burkina Faso. Methodology: We collected demographic and clinical data, and we also performed capillary glucose testing for all the participants aged 16 years and above in five administrative communities in the province of Zandoma. Results: In all, 970 individuals, with a mean age of 49.06 years (SD = 16.97), volunteered to participate in the screening. Most of them were aged between 40 and 65 years old (48.5%) and 57.5% were females. The prevalence of diabetes was 5.7%, and 9% of participants had an FPG level between 1.10 g/l and 1.26 g/l. A family history of diabetes was found in 4.3% of the cases. Looking at the other cardiovascular risk factors, we found 24.3% of the participant to be overweight or obese, 23.6% had High Blood Pressure. Age (p = 0.001), Employment Status (p = 0.015), Body Mass Index (p = 0.036) were significantly associated with diabetes. Conclusion: Diabetes is prevalent in rural areas in Burkina Faso, along with a significant proportion of prediabetes cases. Age, Employment Status, and BMI are the principal associated factors.

[Extra uterine pregnancy and fertilization in vitro about a case of clinical observation at the maternity of the hospital center (ch) de meaux (France)]. / Grossesse extra uterine et fecondation in vitro a propos d'un cas d'observation clinique a la maternite du centre hospitalier (ch) de meaux (France).

Ectopic pregnancy is the leading cause of maternal morbidity and mortality during the first trimester of pregnancy. There has been a dramatic increase in its incidence since the advent of IVF followed by in vitro Embryo Transfer (IVF-ET). Many risk factors related to IVF techniques and the cause of infertility have been documented. The combination of Endo Vaginal Ultrasonography and Human B Chorionic Gonadotropin (HCG) assays is the most reliable diagnostic tool, sometimes allowing the trunk to be preserved.

Grossesse extra-utérine est la principale cause de morbidité et mortalité maternelles durant le premier trimestre de la grossesse. On note une augmentation spectaculaire de son l'incidence depuis l'avènement de la FIV suivi du Transfert de l'Embryon in vitro (FIV-ET). De nombreux facteurs de risque liés aux techniques de la FIV et la cause de l'infertilité ont été documentés. La combinaison de l'échographie Endo vaginale au dosage des B gonadotrophines chorioniques humaines (HCG) est l'outil de diagnostic le plus fiable, permettant parfois de conserver la trompe.

Vacuum pressure combined with osmosonication as an innovative pre-drying technique for Ghanaian ginger: Evidence from the metabolome and quality characteristics of the dried product.

We assessed the impact of selected pretreatment techniques, thus, vacuum-assisted osmotic dehydration (VOD), vacuum-assisted sonication (VSON) and vacuum-assisted osmosonication (VOS) on the metabolomes and quality characteristics of infrared-dried ginger slices. We found marked metabolome differences between the pretreated ginger samples, evidenced by differential amounts of 6-gingerol and 6-shogaol, total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activities. We also found distinct differences in the drying kinetics and sensory characteristics of the pretreated samples. Generally, VOS pretreatment gave the best outcomes. The VOS-pretreated samples contained the highest contents of the marker compounds, TPC, TFC and gave the best antioxidant activity. The VOS-pretreated samples also recorded the shortest drying time and exhibited the best sensory attributes. Overall, the general order observed was, VOS > VSON > VOD > control for all quality parameters examined. VOS pretreatment of ginger before drying therefore holds a great potential for large-scale industrial application.

[Epidemiology and prognosis of eclampsia in Bougouni]. / Epidemiologie et pronostic de l'eclampsie a Bougouni.

OBJECTIVES: The objectives were to describe the epidemiological and prognostic aspects of eclampsia in the Bougouni reference health center. METHODS: This was a transversal prospective, descriptive study from January 1 to December 31, 2015 in the gynecology-obstetrics department of Bougouni reference health center. Were included, all pregnant or postpartum women diagnosed with eclampsia during the study period. RESULTS: The frequency of eclampsia was 2.54%. They were adolescent girls in 50% of cases, primigest in 62.5% of cases, unschooled in 67.5% of cases, having not performed any antenatal care in 70% of cases. Eclampsia occurred in antepartum in 37.5% of cases, in 5% in perpartum and in 57.5% in postpartum. Therapeutically, nicardipine with 72.5% and nifedipine with 22.5% were the antihypertensive drugs used. As for anticonvulsants, magnesium sulfate (MgSO4) was used in 92.5% and diazepam in 7.5%. The maternal-fetal prognosis was marked by 2.5% of maternal death, 27% of prematurity and 27.5% of fetal death in utero. CONCLUSION: Eclampsia is a dreadful pathology with serious maternal and fetal complications.

OBJECTIFS: Les objectifs étaient de décrire les aspects épidémiologique et pronostique de l'éclampsie dans le centre de santé de référence de Bougouni. MÉTHODES: Il s'agissait d'une étude transversale prospective, descriptivedu 1er janvier au 31 décembre 2015 dans le service de gynécologie-obstétrique du centre de santé de référence de Bougouni. Ont été incluses, toutes les femmes enceintes ou les accouchées chez qui le diagnostic de crise d'éclampsie a été retenu pendant la période d'étude. RÉSULTATS: La fréquence de l'éclampsie a été de 2,54%. Il s'agissait d'adolescentes dans 50% des cas, primigestes dans 62,5% des cas, non scolarisées dans 67,5% des cas,n'ayant effectuées aucune consultation prénatale dans70% des cas. L'éclampsie est survenue en antépartumdans 37,5% des cas, dans 5% en perpartum et dans 57,5% en postpartum. Sur le plan thérapeutique, la nicardipine avec 72,5% et la nifédipine avec 22,5% ont été les antihypertenseurs utilisés. Quant aux anticonvulsivants, le sulfate de magnésium (MgSO4) a été utilisé dans 92,5% et le diazépam dans 7,5%. Le pronostic materno-fœtal a été marqué par 2,5% de décès maternel, 27% de prématurité et 27,5% de mort fœtale in-utéro. : L'éclampsie est une pathologie redoutable aux complications maternelles et fœtales graves.

[Primary ileostomy for typhoid-related ileal perforation: a 62-case series in Ouagadougou, Burkina Faso]. / Iléostomie première des perforations iléales d'origine typhique: 62 cas à Ouagadougou (Burkina Faso).

OBJECTIVES: The purpose of this report is to evaluate the efficacy of primary ileostomy for treatment of typhoid-related ileal perforation based on our experience. METHODS: This retrospective study included all cases of typhoid-related ileal perforation treated by primary ileostomy in the Visceral Surgery Department of the Yalgado Ouedraogo Teaching Hospital in Ouagadougou, Burkina Faso from January 2006 to June 2008. Diagnosis was based mainly on peroperative findings revealing specific anatomical lesions. There were 45 men (72.6%) and 17 women (27.4%) with a mean age of 26 years (range, 14 to 68). Asthenic forms were observed in 41 cases (66.1%) and sthenic forms in 21 (33.9%). The mean delay for seeking treatment was 6 days (range, 1 to 30 days). RESULTS: Primary ileostomy was used for treatment of typhoid-related ileal perforation in 78.5% of cases. Most cases (80.6%) involved single perforations. A temporary ileostomy was performed in 55 cases (88.7%) and terminal ileostomy was performed in 7 (11.3%). Complications were observed in 18 patients (29.03%) including suppuration of wall in 8 cases. The mean duration for re-establishing continuity and of hospital stay was 34 and 41 days respectively. Four deaths occurred due to hypovolemic shock. CONCLUSION: In our department, primary ileostomy for typhoid-related ileal perforation reduced mortality despite high morbidity.

[Aseptic nonunion of patella at the Centre Hospitalier Universitaire Bocar Sidy Sall de Kati about 25 cases]. / Pseudarthrose aseptique de la patella au Centre Hospitalier et Universitaire Bocar Sidy Sall (CHU-BSS) de Kati a propos de 25 cas.

OBJECTIVE: The objective of Our study was to describe the epidemiological, clinical, therapeutic and prognostic aspects of Nonunion of patella fractures. PATIENTS METHODS: It was a retrospective study done concerning 25 patients treated fromJanuary 2005 to December 2015 in the orthopedic trauma service CHU Bocar Sidy SALL Kati. RESULTS: We gather together 25 cases of Nonunion of patella fractures disease among 28 caseswhich was about 89.28%. Our patients were divided into 20 men and 5 women, mean age was 36 years, ranging from ages 22 to 75 years. Posttraumatic period was 6-18 months. The initial fracture was neglected in 21 cases and treated in 4 cases. Physical examination revealed lameness in 92% of cases, atrophy of the quadriceps in 56% of cases, joint stiffness, 56% and an inter-fragmentary gap in 92% of patients. The radiographic data were consistent with pseudoarthrosis in all cases. The inter-fragmentary gap was 36 mm on average. The care of our patients was based on plugging and guy-wiring in 64 % of cases and strapping pre- and peri patella in 12% of cases. A partial patellectomy was practiced in 2 cases. A VY plasty of the quadriceps was recommended in 4 cases.The patients were reviewed after a mean of 10 months (8 months- 24 months). Functional outcomes analyzed using Bostman scores were excellent in 4 cases (16%), good in 18 cases (72%) and poor in 3 cases (12%). CONCLUSION: Nonunion of the patella is mostly due to the lack of treatment or wrong treatment leads. Treatment with plugging and guy-wiring seems the most appropriate method.

OBJECTIF: l'objectif de notre étude était décrireles aspects épidémiologiques, cliniques, thérapeutiques et pronostiques de la pseudarthrose de la patella. PATIENTS ET MÉTHODES: Il s'agissait d'une étude rétrospective concernant 25 patients colligés entre janvier 2005 et décembre 2015 dans le service d'orthopédie et de traumatologie du CHU Bocar Sidy SALL de Kati. RÉSULTATS: Nous avons colligé 25 cas de pseudarthrose aseptique de la patella sur 28 cas, soit 89,28%. Nos patients se répartissaient en 20 hommes et 5 femmes. L'âge moyen était de 36 ansavec des extrêmes de 22 et 75 ans. Ledélai post traumatique était de 6-18 mois. La fracture initiale était négligée dans 21 cas et traitée dans 4 cas. L'examen clinique retrouvait une boiterie dans 92%, une amyotrophie du quadriceps dans 56%, une raideur du genou dans 56%, et un vide inter-fragmentaire dans 92%. Les données radiographiques étaient compatibles avec la pseudarthrose de la patella dans tous les cas. L'écart inter-fragmentaire était de 36 mm en moyenne. La prise en charge de nos patients reposait sur l'embrochage-haubanage dans 64%, le cerclage péri-rotulien dans 12%, une patellectomie partielle dans 2 cas (8%) et une plastie du quadriceps en VY était préconisée dans 4 cas (16%). Les patients étaient revus après un recul moyen de 10 mois (8mois-24mois). Les issues fonctionnelles analysées selon le score de Bostman étaient excellentes dans 4 cas (16%), bonnes dans 18 cas (72%) et mauvaises dans 3 cas (12%). CONCLUSION: la pseudarthrose de la patella est surtout le fait de l'absence du traitement ou d'un traitement mal conduit. Le traitement par l'embrochage-haubanage semble la méthode la plus indiquée.

Taxono-genomics and description of Gordonibacter massiliensis sp. nov., a new bacterium isolated from stool of healthy patient.

Using the taxono-genomics concept, we describe here a strictly anaerobic Gram-positive bacillus. This strain was isolated from the stool sample of a 50-year-old healthy Bedouin woman. The 16S rRNA gene sequence analysis and the whole-genome sequencing showed that this isolate belonged to the genus Gordonibacter in the family Eggerthellaceae. Based on these criteria, we propose the creation of Gordonibacter massiliensis sp. nov., strain Marseille-P2775T (= CSUR P2775).

Detailed description of Senegalia massiliensis strain SIT17T , a bacterium isolated from the human gut.

Strain SIT17T was isolated from the stool of a healthy 13-month-old Senegalese boy. It is a Gram-positive, anaerobic, rod-shaped, non-spore-forming and mobile bacterium. It exhibited 92.74% 16S rRNA gene sequence similarity with the Brassicibacter thermophilus strain Cel2f, the phylogenetically most closely related species. Its genome is about 2.87 Mb long with 27.39 mol% G + C content. We provide more details of Senegalia massiliensis strain SIT17T (= CSURP2130 = DSM 103071), the creation of which was previously announced.