Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer.

Wasko, Urszula N; Jiang, Jingjing; Dalton, Tanner C; Curiel-Garcia, Alvaro; Edwards, A Cole; Wang, Yingyun; Lee, Bianca; Orlen, Margo; Tian, Sha; Stalnecker, Clint A; Drizyte-Miller, Kristina; Menard, Marie; Dilly, Julien; Sastra, Stephen A; Palermo, Carmine F; Hasselluhn, Marie C; Decker-Farrell, Amanda R; Chang, Stephanie; Jiang, Lingyan; Wei, Xing; Yang, Yu C; Helland, Ciara; Courtney, Haley; Gindin, Yevgeniy; Muonio, Karl; Zhao, Ruiping; Kemp, Samantha B; Clendenin, Cynthia; Sor, Rina; Vostrejs, William P; Hibshman, Priya S; Amparo, Amber M; Hennessey, Connor; Rees, Matthew G; Ronan, Melissa M; Roth, Jennifer A; Brodbeck, Jens; Tomassoni, Lorenzo; Bakir, Basil; Socci, Nicholas D; Herring, Laura E; Barker, Natalie K; Wang, Junning; Cleary, James M; Wolpin, Brian M; Chabot, John A; Kluger, Michael D; Manji, Gulam A; Tsai, Kenneth Y; Sekulic, Miroslav.

Nature ; 2024 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-38588697

2.

Editorial Expression of Concern: p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.

Flores, Elsa R; Tsai, Kenneth Y; Crowley, Denise; Sengupta, Shomit; Yang, Annie; McKeon, Frank; Jacks, Tyler.

Nature ; 627(8004): E10, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38418890

3.

Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.

Aiderus, Aziz; Newberg, Justin Y; Guzman-Rojas, Liliana; Contreras-Sandoval, Ana M; Meshey, Amanda L; Jones, Devin J; Amaya-Manzanares, Felipe; Rangel, Roberto; Ward, Jerrold M; Lee, Song-Choon; Ban, Kenneth Hon-Kim; Rogers, Keith; Rogers, Susan M; Selvanesan, Luxmanan; McNoe, Leslie A; Copeland, Neal G; Jenkins, Nancy A; Tsai, Kenneth Y; Black, Michael A; Mann, Karen M; Mann, Michael B.

PLoS Genet ; 17(8): e1009094, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34398873

4.

Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial.

Kim, Sungjune; Wuthrick, Evan; Blakaj, Dukagjin; Eroglu, Zeynep; Verschraegen, Claire; Thapa, Ram; Mills, Matthew; Dibs, Khaled; Liveringhouse, Casey; Russell, Jeffery; Caudell, Jimmy J; Tarhini, Ahmad; Markowitz, Joseph; Kendra, Kari; Wu, Richard; Chen, Dung-Tsa; Berglund, Anders; Michael, Lauren; Aoki, Mia; Wang, Min-Hsuan; Hamaidi, Imene; Cheng, Pingyan; de la Iglesia, Janis; Slebos, Robbert J; Chung, Christine H; Knepper, Todd C; Moran-Segura, Carlos M; Nguyen, Jonathan V; Perez, Bradford A; Rose, Trevor; Harrison, Louis; Messina, Jane L; Sondak, Vernon K; Tsai, Kenneth Y; Khushalani, Nikhil I; Brohl, Andrew S.

Lancet ; 400(10357): 1008-1019, 2022 09 24.

Artigo em Inglês | MEDLINE | ID: mdl-36108657

5.

Molecular and immune targets in cutaneous squamous cell carcinoma.

Galambus, Justine; Tsai, Kenneth Y.

Mol Carcinog ; 62(1): 38-51, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36000298

6.

spatialGE: quantification and visualization of the tumor microenvironment heterogeneity using spatial transcriptomics.

Ospina, Oscar E; Wilson, Christopher M; Soupir, Alex C; Berglund, Anders; Smalley, Inna; Tsai, Kenneth Y; Fridley, Brooke L.

Bioinformatics ; 38(9): 2645-2647, 2022 04 28.

Artigo em Inglês | MEDLINE | ID: mdl-35258565

7.

Microbiome modulates immunotherapy response in cutaneous squamous cell carcinoma.

Voigt, Anita Y; Walter, Andrew; Young, Timothy H; Graham, John P; Batista Bittencourt, Bruna M; de Mingo Pulido, Alvaro; Prieto, Karol; Tsai, Kenneth Y; Sundberg, John P; Oh, Julia.

Exp Dermatol ; 32(10): 1624-1632, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37350109

8.

Melanoma and CLL co-occurrence and survival: role of KC history.

Zhao, Yayi; Amorrortu, Rossybelle P; Stewart, Sandra C; Ghia, Kavita M; Williams, Vonetta L; Sondak, Vernon K; Tsai, Kenneth Y; Pinilla-Ibarz, Javier; Chavez, Julio C; Rollison, Dana E.

BMC Cancer ; 23(1): 1084, 2023 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-37946198

9.

An Internally Validated Prognostic Risk-Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma.

Shannon, Adrienne B; Straker, Richard J; Carr, Michael J; Sun, James; Landa, Karenia; Baecher, Kirsten; Lynch, Kevin; Bartels, Harrison G; Panchaud, Robyn; Keele, Luke J; Lowe, Michael C; Slingluff, Craig L; Jameson, Mark J; Tsai, Kenneth Y; Faries, Mark B; Beasley, Georgia M; Sondak, Vernon K; Karakousis, Giorgos C; Zager, Jonathan S; Miura, John T.

Ann Surg Oncol ; 29(11): 7033-7044, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35867209

10.

Molecular cancer prevention: Current status and future directions.

Maresso, Karen Colbert; Tsai, Kenneth Y; Brown, Powel H; Szabo, Eva; Lippman, Scott; Hawk, Ernest T.

CA Cancer J Clin ; 65(5): 345-83, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26284997

11.

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.

Venkatanarayan, Avinashnarayan; Raulji, Payal; Norton, William; Chakravarti, Deepavali; Coarfa, Cristian; Su, Xiaohua; Sandur, Santosh K; Ramirez, Marc S; Lee, Jaehuk; Kingsley, Charles V; Sananikone, Eliot F; Rajapakshe, Kimal; Naff, Katherine; Parker-Thornburg, Jan; Bankson, James A; Tsai, Kenneth Y; Gunaratne, Preethi H; Flores, Elsa R.

Nature ; 517(7536): 626-30, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25409149

12.

MicroRNA heterogeneity in melanoma progression.

Thyagarajan, Anita; Tsai, Kenneth Y; Sahu, Ravi P.

Semin Cancer Biol ; 59: 208-220, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31163254

13.

Molecular and immune targets for Merkel cell carcinoma therapy and prevention.

Cohen, Leah; Tsai, Kenneth Y.

Mol Carcinog ; 58(9): 1602-1611, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31116890

14.

Targeting ERK beyond the boundaries of the kinase active site in melanoma.

Sammons, Rachel M; Ghose, Ranajeet; Tsai, Kenneth Y; Dalby, Kevin N.

Mol Carcinog ; 58(9): 1551-1570, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31190430

15.

Patterns of recurrence and prognosis in pathologic stage I and II Merkel cell carcinoma: A multicenter, retrospective cohort analysis.

Tieniber, Andrew D; Shannon, Adrienne B; Carr, Michael J; Sun, James; Landa, Karenia; Baecher, Kirsten M; Lynch, Kevin; Bartels, Harrison G; Panchaud, Robyn; Lowe, Michael C; Slingluff, Craig L; Jameson, Mark J; Tsai, Kenneth Y; Faries, Mark B; Beasley, Georgia M; Sondak, Vernon K; Karakousis, Giorgos C; Zager, Jonathan S; Miura, John T.

J Am Acad Dermatol ; 88(1): 251-253, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-35588924

16.

ASO Visual Abstract: An Internally Validated Prognostic Risk Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma.

Shannon, Adrienne B; Straker, Richard J; Carr, Michael J; Sun, James; Landa, Karenia; Baecher, Kirsten; Lynch, Kevin; Bartels, Harrison G; Panchaud, Robyn; Keele, Luke J; Lowe, Michael C; Slingluff, Craig L; Jameson, Mark J; Tsai, Kenneth Y; Faries, Mark B; Beasley, Georgia M; Sondak, Vernon K; Karakousis, Giorgos C; Zager, Jonathan S; Miura, John T.

Ann Surg Oncol ; 29(11): 7045-7046, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35896923

17.

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

Chakravarti, Deepavali; Su, Xiaohua; Cho, Min Soon; Bui, Ngoc Hoang Bao; Coarfa, Cristian; Venkatanarayan, Avinashnarayan; Benham, Ashley L; Flores González, Ramón E; Alana, Jennifer; Xiao, Weimin; Leung, Marco L; Vin, Harina; Chan, Io Long; Aquino, Arianexys; Müller, Nicole; Wang, Hongran; Cooney, Austin J; Parker-Thornburg, Jan; Tsai, Kenneth Y; Gunaratne, Preethi H; Flores, Elsa R.

Proc Natl Acad Sci U S A ; 111(5): E572-81, 2014 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-24449888

18.

Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial.

Fowler, Nathan H; Davis, R Eric; Rawal, Seema; Nastoupil, Loretta; Hagemeister, Fredrick B; McLaughlin, Peter; Kwak, Larry W; Romaguera, Jorge E; Fanale, Michelle A; Fayad, Luis E; Westin, Jason R; Shah, Jatin; Orlowski, Robert Z; Wang, Michael; Turturro, Francesco; Oki, Yasuhiro; Claret, Linda C; Feng, Lei; Baladandayuthapani, Veerabhadran; Muzzafar, Tariq; Tsai, Kenneth Y; Samaniego, Felipe; Neelapu, Sattva S.

Lancet Oncol ; 15(12): 1311-8, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25439689

19.

Histological features associated with vemurafenib-induced skin toxicities: examination of 141 cutaneous lesions biopsied during therapy.

Curry, Jonathan L; Tetzlaff, Michael T; Nicholson, Kimberly; Duvic, Madeleine; Kim, Kevin B; Tsai, Kenneth Y; Hwu, Wen-Jen; Hong, David S; Prieto, Victor G; Torres-Cabala, Carlos A.

Am J Dermatopathol ; 36(7): 557-61, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24950418

20.

Precision medicine.

Tsai, Kenneth Y.

Semin Cutan Med Surg ; 33(2): 59, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25085662

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