Detalhe da pesquisa
1.
The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
Annu Rev Physiol
; 83: 127-151, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228454
2.
GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS.
Int J Obes (Lond)
; 43(12): 2370-2380, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31152154
3.
Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification.
J Cell Sci
; 125(Pt 22): 5479-88, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956539
4.
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.
Nat Med
; 13(11): 1333-40, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17982462
5.
GDF15 analogs as obesity therapeutics.
Cell Metab
; 35(2): 227-228, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754014
6.
GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
Cell Metab
; 35(8): 1341-1355.e3, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433299
7.
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease.
Nephrol Dial Transplant
; 27(1): 70-5, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21940482
8.
Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity.
PLoS One
; 15(6): e0233846, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32502202
9.
Targeting the divergent TGFß superfamily cytokine MIC-1/GDF15 for therapy of anorexia/cachexia syndromes.
Curr Opin Support Palliat Care
; 12(4): 404-409, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30382947
10.
Targeting Obesity and Cachexia: Identification of the GFRAL Receptor-MIC-1/GDF15 Pathway.
Trends Mol Med
; 23(12): 1065-1067, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29129392
11.
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice.
PLoS One
; 10(2): e0115189, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25695521
12.
Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.
PLoS One
; 10(7): e0133362, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26207898
13.
The anorectic actions of the TGFß cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract.
PLoS One
; 9(6): e100370, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24971956
14.
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator.
PLoS One
; 8(2): e55174, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468844
15.
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets.
PLoS One
; 7(4): e34868, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22514681
16.
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice.
PLoS One
; 7(8): e43833, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22952779