Detalhe da pesquisa
1.
Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold.
Arthritis Rheum
; 62(7): 1933-43, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506263
2.
Fc optimization of therapeutic antibodies enhances their ability to kill tumor cells in vitro and controls tumor expansion in vivo via low-affinity activating Fcgamma receptors.
Cancer Res
; 67(18): 8882-90, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17875730
3.
Endotoxin-induced uveitis in cyclooxygenase-2-deficient mice.
Invest Ophthalmol Vis Sci
; 45(7): 2306-13, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15223810
4.
MCP-1 expression in endotoxin-induced uveitis.
Invest Ophthalmol Vis Sci
; 43(5): 1493-8, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11980865
5.
Nonclinical evaluation of GMA161--an antihuman CD16 (FcγRIII) monoclonal antibody for treatment of autoimmune disorders in CD16 transgenic mice.
Toxicol Sci
; 125(1): 299-309, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22025730
6.
Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion.
J Mol Biol
; 399(3): 436-49, 2010 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20382161
7.
CD32B, the human inhibitory Fc-gamma receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma.
Blood
; 108(7): 2384-91, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16757681
8.
Expression of chemokine receptors, CXCR4 and CXCR5, and chemokines, BLC and SDF-1, in the eyes of patients with primary intraocular lymphoma.
Ophthalmology
; 110(2): 421-6, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12578791
9.
Effect of sex hormones on experimental autoimmune uveoretinitis (EAU).
Immunol Invest
; 32(4): 259-73, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14603994
10.
Enhancing the potency of therapeutic monoclonal antibodies via Fc optimization.
Adv Enzyme Regul
; 48: 152-64, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18177741