Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Relatlimab and nivolumab in the treatment of melanoma.

Au, Lewis; Larkin, James; Turajlic, Samra.

Cell ; 185(26): 4866-4869, 2022 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-36563660

2.

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.

Litchfield, Kevin; Reading, James L; Puttick, Clare; Thakkar, Krupa; Abbosh, Chris; Bentham, Robert; Watkins, Thomas B K; Rosenthal, Rachel; Biswas, Dhruva; Rowan, Andrew; Lim, Emilia; Al Bakir, Maise; Turati, Virginia; Guerra-Assunção, José Afonso; Conde, Lucia; Furness, Andrew J S; Saini, Sunil Kumar; Hadrup, Sine R; Herrero, Javier; Lee, Se-Hoon; Van Loo, Peter; Enver, Tariq; Larkin, James; Hellmann, Matthew D; Turajlic, Samra; Quezada, Sergio A; McGranahan, Nicholas; Swanton, Charles.

Cell ; 184(3): 596-614.e14, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-33508232

3.

Cancer, COVID-19, and Antiviral Immunity: The CAPTURE Study.

Au, Lewis; Boos, Laura Amanda; Swerdlow, Anthony; Byrne, Fiona; Shepherd, Scott T C; Fendler, Annika; Turajlic, Samra.

Cell ; 183(1): 4-10, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32979319

4.

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

Mitchell, Thomas J; Turajlic, Samra; Rowan, Andrew; Nicol, David; Farmery, James H R; O'Brien, Tim; Martincorena, Inigo; Tarpey, Patrick; Angelopoulos, Nicos; Yates, Lucy R; Butler, Adam P; Raine, Keiran; Stewart, Grant D; Challacombe, Ben; Fernando, Archana; Lopez, Jose I; Hazell, Steve; Chandra, Ashish; Chowdhury, Simon; Rudman, Sarah; Soultati, Aspasia; Stamp, Gordon; Fotiadis, Nicos; Pickering, Lisa; Au, Lewis; Spain, Lavinia; Lynch, Joanna; Stares, Mark; Teague, Jon; Maura, Francesco; Wedge, David C; Horswell, Stuart; Chambers, Tim; Litchfield, Kevin; Xu, Hang; Stewart, Aengus; Elaidi, Reza; Oudard, Stéphane; McGranahan, Nicholas; Csabai, Istvan; Gore, Martin; Futreal, P Andrew; Larkin, James; Lynch, Andy G; Szallasi, Zoltan; Swanton, Charles; Campbell, Peter J.

Cell ; 173(3): 611-623.e17, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656891

5.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic, Samra; Xu, Hang; Litchfield, Kevin; Rowan, Andrew; Horswell, Stuart; Chambers, Tim; O'Brien, Tim; Lopez, Jose I; Watkins, Thomas B K; Nicol, David; Stares, Mark; Challacombe, Ben; Hazell, Steve; Chandra, Ashish; Mitchell, Thomas J; Au, Lewis; Eichler-Jonsson, Claudia; Jabbar, Faiz; Soultati, Aspasia; Chowdhury, Simon; Rudman, Sarah; Lynch, Joanna; Fernando, Archana; Stamp, Gordon; Nye, Emma; Stewart, Aengus; Xing, Wei; Smith, Jonathan C; Escudero, Mickael; Huffman, Adam; Matthews, Nik; Elgar, Greg; Phillimore, Ben; Costa, Marta; Begum, Sharmin; Ward, Sophia; Salm, Max; Boeing, Stefan; Fisher, Rosalie; Spain, Lavinia; Navas, Carolina; Grönroos, Eva; Hobor, Sebastijan; Sharma, Sarkhara; Aurangzeb, Ismaeel; Lall, Sharanpreet; Polson, Alexander; Varia, Mary; Horsfield, Catherine; Fotiadis, Nicos.

Cell ; 173(3): 595-610.e11, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656894

6.

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

Turajlic, Samra; Xu, Hang; Litchfield, Kevin; Rowan, Andrew; Chambers, Tim; Lopez, Jose I; Nicol, David; O'Brien, Tim; Larkin, James; Horswell, Stuart; Stares, Mark; Au, Lewis; Jamal-Hanjani, Mariam; Challacombe, Ben; Chandra, Ashish; Hazell, Steve; Eichler-Jonsson, Claudia; Soultati, Aspasia; Chowdhury, Simon; Rudman, Sarah; Lynch, Joanna; Fernando, Archana; Stamp, Gordon; Nye, Emma; Jabbar, Faiz; Spain, Lavinia; Lall, Sharanpreet; Guarch, Rosa; Falzon, Mary; Proctor, Ian; Pickering, Lisa; Gore, Martin; Watkins, Thomas B K; Ward, Sophia; Stewart, Aengus; DiNatale, Renzo; Becerra, Maria F; Reznik, Ed; Hsieh, James J; Richmond, Todd A; Mayhew, George F; Hill, Samantha M; McNally, Catherine D; Jones, Carol; Rosenbaum, Heidi; Stanislaw, Stacey; Burgess, Daniel L; Alexander, Nelson R; Swanton, Charles.

Cell ; 173(3): 581-594.e12, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656895

7.

SnapShot: Renal Cell Carcinoma.

Turajlic, Samra; Larkin, James; Swanton, Charles.

Cell ; 163(6): 1556-1556.e1, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26638079

8.

Antibodies against endogenous retroviruses promote lung cancer immunotherapy.

Ng, Kevin W; Boumelha, Jesse; Enfield, Katey S S; Almagro, Jorge; Cha, Hongui; Pich, Oriol; Karasaki, Takahiro; Moore, David A; Salgado, Roberto; Sivakumar, Monica; Young, George; Molina-Arcas, Miriam; de Carné Trécesson, Sophie; Anastasiou, Panayiotis; Fendler, Annika; Au, Lewis; Shepherd, Scott T C; Martínez-Ruiz, Carlos; Puttick, Clare; Black, James R M; Watkins, Thomas B K; Kim, Hyemin; Shim, Seohee; Faulkner, Nikhil; Attig, Jan; Veeriah, Selvaraju; Magno, Neil; Ward, Sophia; Frankell, Alexander M; Al Bakir, Maise; Lim, Emilia L; Hill, Mark S; Wilson, Gareth A; Cook, Daniel E; Birkbak, Nicolai J; Behrens, Axel; Yousaf, Nadia; Popat, Sanjay; Hackshaw, Allan; Hiley, Crispin T; Litchfield, Kevin; McGranahan, Nicholas; Jamal-Hanjani, Mariam; Larkin, James; Lee, Se-Hoon; Turajlic, Samra; Swanton, Charles; Downward, Julian; Kassiotis, George.

Nature ; 616(7957): 563-573, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37046094

9.

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

Arce Vargas, Frederick; Furness, Andrew J S; Solomon, Isabelle; Joshi, Kroopa; Mekkaoui, Leila; Lesko, Marta H; Miranda Rota, Enrique; Dahan, Rony; Georgiou, Andrew; Sledzinska, Anna; Ben Aissa, Assma; Franz, Dafne; Werner Sunderland, Mariana; Wong, Yien Ning Sophia; Henry, Jake Y; O'Brien, Tim; Nicol, David; Challacombe, Ben; Beers, Stephen A; Turajlic, Samra; Gore, Martin; Larkin, James; Swanton, Charles; Chester, Kerry A; Pule, Martin; Ravetch, Jeffrey V; Marafioti, Teresa; Peggs, Karl S; Quezada, Sergio A.

Immunity ; 46(4): 577-586, 2017 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-28410988

10.

Author Correction: Resolving genetic heterogeneity in cancer.

Turajlic, Samra; Sottoriva, Andrea; Graham, Trevor; Swanton, Charles.

Nat Rev Genet ; 21(1): 65, 2020 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-31659302

11.

Pervasive chromosomal instability and karyotype order in tumour evolution.

Watkins, Thomas B K; Lim, Emilia L; Petkovic, Marina; Elizalde, Sergi; Birkbak, Nicolai J; Wilson, Gareth A; Moore, David A; Grönroos, Eva; Rowan, Andrew; Dewhurst, Sally M; Demeulemeester, Jonas; Dentro, Stefan C; Horswell, Stuart; Au, Lewis; Haase, Kerstin; Escudero, Mickael; Rosenthal, Rachel; Bakir, Maise Al; Xu, Hang; Litchfield, Kevin; Lu, Wei Ting; Mourikis, Thanos P; Dietzen, Michelle; Spain, Lavinia; Cresswell, George D; Biswas, Dhruva; Lamy, Philippe; Nordentoft, Iver; Harbst, Katja; Castro-Giner, Francesc; Yates, Lucy R; Caramia, Franco; Jaulin, Fanny; Vicier, Cécile; Tomlinson, Ian P M; Brastianos, Priscilla K; Cho, Raymond J; Bastian, Boris C; Dyrskjøt, Lars; Jönsson, Göran B; Savas, Peter; Loi, Sherene; Campbell, Peter J; Andre, Fabrice; Luscombe, Nicholas M; Steeghs, Neeltje; Tjan-Heijnen, Vivianne C G; Szallasi, Zoltan; Turajlic, Samra; Jamal-Hanjani, Mariam.

Nature ; 587(7832): 126-132, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32879494

12.

Resolving genetic heterogeneity in cancer.

Turajlic, Samra; Sottoriva, Andrea; Graham, Trevor; Swanton, Charles.

Nat Rev Genet ; 20(7): 404-416, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30918367

13.

Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases.

Yngvadottir, Bryndis; Andreou, Avgi; Bassaganyas, Laia; Larionov, Alexey; Cornish, Alex J; Chubb, Daniel; Saunders, Charlie N; Smith, Philip S; Zhang, Huairen; Cole, Yasemin; Research Consortium, Genomics England; Larkin, James; Browning, Lisa; Turajlic, Samra; Litchfield, Kevin; Houlston, Richard S; Maher, Eamonn R.

Hum Mol Genet ; 31(17): 3001-3011, 2022 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-35441217

14.

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Abbosh, Christopher; Birkbak, Nicolai J; Wilson, Gareth A; Jamal-Hanjani, Mariam; Constantin, Tudor; Salari, Raheleh; Le Quesne, John; Moore, David A; Veeriah, Selvaraju; Rosenthal, Rachel; Marafioti, Teresa; Kirkizlar, Eser; Watkins, Thomas B K; McGranahan, Nicholas; Ward, Sophia; Martinson, Luke; Riley, Joan; Fraioli, Francesco; Al Bakir, Maise; Grönroos, Eva; Zambrana, Francisco; Endozo, Raymondo; Bi, Wenya Linda; Fennessy, Fiona M; Sponer, Nicole; Johnson, Diana; Laycock, Joanne; Shafi, Seema; Czyzewska-Khan, Justyna; Rowan, Andrew; Chambers, Tim; Matthews, Nik; Turajlic, Samra; Hiley, Crispin; Lee, Siow Ming; Forster, Martin D; Ahmad, Tanya; Falzon, Mary; Borg, Elaine; Lawrence, David; Hayward, Martin; Kolvekar, Shyam; Panagiotopoulos, Nikolaos; Janes, Sam M; Thakrar, Ricky; Ahmed, Asia; Blackhall, Fiona; Summers, Yvonne; Hafez, Dina; Naik, Ashwini.

Nature ; 554(7691): 264, 2018 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-29258292

15.

Predictive biomarkers for response to immune checkpoint inhibition.

Shum, Benjamin; Larkin, James; Turajlic, Samra.

Semin Cancer Biol ; 79: 4-17, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-33819567

16.

Optimisation of b-values for the accurate estimation of the apparent diffusion coefficient (ADC) in whole-body diffusion-weighted MRI in patients with metastatic melanoma.

Knill, Annemarie K; Blackledge, Matthew D; Curcean, Andra; Larkin, James; Turajlic, Samra; Riddell, Angela; Koh, Dow Mu; Messiou, Christina; Winfield, Jessica M.

Eur Radiol ; 33(2): 863-871, 2023 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-36169688

17.

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Abbosh, Christopher; Birkbak, Nicolai J; Wilson, Gareth A; Jamal-Hanjani, Mariam; Constantin, Tudor; Salari, Raheleh; Le Quesne, John; Moore, David A; Veeriah, Selvaraju; Rosenthal, Rachel; Marafioti, Teresa; Kirkizlar, Eser; Watkins, Thomas B K; McGranahan, Nicholas; Ward, Sophia; Martinson, Luke; Riley, Joan; Fraioli, Francesco; Al Bakir, Maise; Grönroos, Eva; Zambrana, Francisco; Endozo, Raymondo; Bi, Wenya Linda; Fennessy, Fiona M; Sponer, Nicole; Johnson, Diana; Laycock, Joanne; Shafi, Seema; Czyzewska-Khan, Justyna; Rowan, Andrew; Chambers, Tim; Matthews, Nik; Turajlic, Samra; Hiley, Crispin; Lee, Siow Ming; Forster, Martin D; Ahmad, Tanya; Falzon, Mary; Borg, Elaine; Lawrence, David; Hayward, Martin; Kolvekar, Shyam; Panagiotopoulos, Nikolaos; Janes, Sam M; Thakrar, Ricky; Ahmed, Asia; Blackhall, Fiona; Summers, Yvonne; Hafez, Dina; Naik, Ashwini.

Nature ; 545(7655): 446-451, 2017 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-28445469

18.

What's new in WHO fifth edition - urinary tract.

Compérat, Eva; Amin, Mahul B; Berney, Dan M; Cree, Ian; Menon, Santosh; Moch, Holger; Netto, George J; Rao, Vishal; Raspollini, Maria Rosaria; Rubin, Mark A; Srigley, John R; Tan, Puay Hoon; Tickoo, Satish Kumar; Turajlic, Samra; Tsuzuki, Toyonori.

Histopathology ; 81(4): 439-446, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35942645

19.

An introduction to the WHO 5th edition 2022 classification of testicular tumours.

Berney, Daniel M; Cree, Ian; Rao, Vishal; Moch, Holger; Srigley, John R; Tsuzuki, Toyonori; Amin, Mahul B; Comperat, Eva M; Hartmann, Arndt; Menon, Santosh; Netto, George J; Rubin, Mark A; Turajlic, Samra; Raspollini, Maria R; Tickoo, Satish K.

Histopathology ; 81(4): 459-466, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35502823

20.

WHO 2022 landscape of papillary and chromophobe renal cell carcinoma.

Lobo, João; Ohashi, Riuko; Amin, Mahul B; Berney, Daniel M; Compérat, Eva M; Cree, Ian A; Gill, Anthony J; Hartmann, Arndt; Menon, Santosh; Netto, George J; Raspollini, Maria R; Rubin, Mark A; Tan, Puay Hoon; Tickoo, Satish K; Tsuzuki, Toyonori; Turajlic, Samra; Zhou, Ming; Srigley, John R; Moch, Holger.

Histopathology ; 81(4): 426-438, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35596618

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