Detalhe da pesquisa
1.
Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.
Proc Natl Acad Sci U S A
; 118(28)2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260399
2.
Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.
Nat Immunol
; 12(12): 1184-93, 2011 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22019834
3.
Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme.
Immunity
; 38(5): 896-905, 2013 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23602765
4.
Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice.
Proc Natl Acad Sci U S A
; 116(23): 11380-11389, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31097594
5.
Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
Proc Natl Acad Sci U S A
; 115(49): E11523-E11531, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442666
6.
Creatine maintains intestinal homeostasis and protects against colitis.
Proc Natl Acad Sci U S A
; 114(7): E1273-E1281, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137860
7.
The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.
Immunity
; 33(2): 181-91, 2010 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20705491
8.
Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Proc Natl Acad Sci U S A
; 113(42): E6418-E6426, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27708159
9.
Real-time resolution of point mutations that cause phenovariance in mice.
Proc Natl Acad Sci U S A
; 112(5): E440-9, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605905
10.
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals.
Immunity
; 28(3): 381-90, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18342009
11.
ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development.
Nature
; 457(7231): 906-9, 2009 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19060883
12.
Structural basis for Retriever-SNX17 assembly and endosomal sorting.
bioRxiv
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38559023
13.
The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation.
Dis Model Mech
; 16(9)2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37589563
14.
Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation.
Nat Commun
; 14(1): 3652, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339972
15.
SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity.
Science
; 372(6543)2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33986151
16.
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation.
Sci Immunol
; 5(43)2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980486
17.
A potential novel use for direct antiviral therapy.
Hepatology
; 57(1): 414-5, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23172611
18.
Research Techniques Made Simple: Forward Genetic Screening to Uncover Genes Involved in Skin Biology.
J Invest Dermatol
; 139(9): 1848-1853.e1, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445571
19.
A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis.
Dis Model Mech
; 11(12)2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563851
20.
Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.
Cell Rep
; 24(9): 2342-2355, 2018 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157428