Detalhe da pesquisa
1.
Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.
Cell
; 159(6): 1300-11, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480295
2.
Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases.
Cell
; 143(7): 1110-20, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21183074
3.
In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS) Program.
Antimicrob Agents Chemother
; 67(1): e0128122, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36541767
4.
SEDS proteins are a widespread family of bacterial cell wall polymerases.
Nature
; 537(7622): 634-638, 2016 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27525505
5.
Microbiological Characterization of VNRX-5236, a Broad-Spectrum ß-Lactamase Inhibitor for Rescue of the Orally Bioavailable Cephalosporin Ceftibuten as a Carbapenem-Sparing Agent against Strains of Enterobacterales Expressing Extended-Spectrum ß-Lactamases and Serine Carbapenemases.
Antimicrob Agents Chemother
; 65(8): e0055221, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001510
6.
Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
J Am Chem Soc
; 142(9): 4445-4455, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064871
7.
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-ß-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871094
8.
Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30323039
9.
Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity.
Proc Natl Acad Sci U S A
; 113(17): 4788-93, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27071112
10.
Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide.
J Biol Chem
; 292(48): 19840-19848, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018092
11.
Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061293
12.
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Bioorg Med Chem Lett
; 28(4): 748-755, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29336873
13.
A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis.
Genes Dev
; 24(4): 411-22, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159959
14.
Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site.
Mol Microbiol
; 89(4): 690-701, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23796240
15.
Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis.
EMBO J
; 29(8): 1412-22, 2010 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20300061
16.
An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring.
Proc Natl Acad Sci U S A
; 108(45): E1052-60, 2011 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22006326
17.
Effects of delayed metamorphosis on larval survival, metamorphosis, and juvenile performance of four closely related species of tropical sea urchins (genus Echinometra).
ScientificWorldJournal
; 2014: 918028, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24624048
18.
Adhesive-Free Adhesion between Plasma-Treated Glass-Cloth-Containing Polytetrafluoroethylene (GC-PTFE) and Stainless Steel: Comparison between GC-PTFE and Pure PTFE.
Polymers (Basel)
; 14(3)2022 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35160384
19.
The Next-Generation ß-Lactamase Inhibitor Taniborbactam Restores the Morphological Effects of Cefepime in KPC-Producing Escherichia coli.
Microbiol Spectr
; 9(2): e0091821, 2021 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34494877
20.
Concomitant use of 18F-FDG PET-CT SUVmax is useful in the assessment of Ki67 labeling index in core-needle biopsy specimens of breast cancer.
Gland Surg
; 10(1): 1-9, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33633957