Detalhe da pesquisa
1.
Discovery of new low-molecular-weight p53-Mdmx disruptors and their anti-cancer activities.
Bioorg Med Chem
; 24(8): 1919-26, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27010502
2.
Synergistic antitumor effect of a combination of paclitaxel and carboplatin with nobiletin from Citrus depressa on non-small-cell lung cancer cell lines.
Planta Med
; 80(6): 452-7, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24687742
3.
Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models.
Biochem Biophys Res Commun
; 433(4): 456-62, 2013 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23501104
4.
Isozyme-specific histone deacetylase 1/2 inhibitor K560 attenuates oxidative stress-induced retinal cell death.
Neurosci Lett
; 793: 136978, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435210
5.
Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl)benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain.
Bioorg Med Chem Lett
; 22(5): 1926-30, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22321215
6.
[Isoform Selectivity of HDAC Inhibitors Has a Significant Effect on PD-L1 Expression in the Triple-negative Cancer Cell Line MDA-MB-231].
Yakugaku Zasshi
; 142(4): 431-437, 2022.
Artigo
em Japonês
| MEDLINE | ID: mdl-35370198
7.
MDMX elevation by a novel Mdmx-p53 interaction inhibitor mitigates neuronal damage after ischemic stroke.
Sci Rep
; 12(1): 21110, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36473920
8.
New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl group.
Bioorg Med Chem
; 19(13): 3995-4003, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21664138
9.
Antitumor effect of liposomal histone deacetylase inhibitor-lipid conjugates in vitro.
Chem Pharm Bull (Tokyo)
; 59(11): 1386-92, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22041075
10.
New orally bioavailable 2-aminobenzamide-type histone deacetylase inhibitor possessing a (2-hydroxyethyl)(4-(thiophen-2-yl)benzyl)amino group.
Bioorg Med Chem
; 18(11): 3925-33, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20452226
11.
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
Biol Pharm Bull
; 33(7): 1199-205, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20606313
12.
Attempt to detect natural anticancer compounds--protein binding through precursor ion scan and MS/MS measurements.
Yakugaku Zasshi
; 128(9): 1317-23, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18758146
13.
New 5-Aryl-Substituted 2-Aminobenzamide-Type HDAC Inhibitors with a Diketopiperazine Group and Their Ameliorating Effects on Ischemia-Induced Neuronal Cell Death.
Sci Rep
; 8(1): 1400, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29362442
14.
Potential Application of 5-Aryl-Substituted 2-Aminobenzamide Type of HDAC1/2- Selective Inhibitors to Pharmaceuticals.
Curr Pharm Des
; 23(40): 6149-6159, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27928959
15.
Cytoprotective effect of novel histone deacetylase inhibitors against polyglutamine toxicity.
Neurosci Lett
; 392(3): 213-5, 2006 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16199124
16.
A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease.
Neurobiol Aging
; 37: 103-116, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26545632
17.
NGF-induced phosphatidylinositol 3-kinase signaling pathway prevents thapsigargin-triggered ER stress-mediated apoptosis in PC12 cells.
Neurosci Lett
; 389(3): 124-8, 2005 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16095815
18.
Effect of 3-O-octanoyl-(+)-catechin on the responses of GABA(A) receptors and Na+/glucose cotransporters expressed in xenopus oocytes and on the oocyte membrane potential.
J Agric Food Chem
; 53(6): 1955-9, 2005 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15769120
19.
Influence of the carbamate fungicide benomyl on the gene expression and activity of aromatase in the human breast carcinoma cell line MCF-7.
Environ Toxicol Pharmacol
; 39(1): 292-9, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25543211
20.
Anti-Staphylococcus aureus activity and oxacillin resistance modulating capacity of 3-O-acyl-catechins.
Int J Antimicrob Agents
; 24(4): 374-80, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15380264