Detalhe da pesquisa
1.
Involvement of Extracellular Vesicles in the Proinflammatory Response to Clozapine: Implications for Clozapine-Induced Agranulocytosis.
J Pharmacol Exp Ther
; 388(3): 827-845, 2024 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38262745
2.
The Emerging Role of the Innate Immune Response in Idiosyncratic Drug Reactions.
Pharmacol Rev
; 73(3): 861-896, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34016669
3.
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash.
Chem Res Toxicol
; 36(11): 1711-1716, 2023 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37922508
4.
The Role of Myeloperoxidase in Clozapine-Induced Inflammation: A Mechanistic Update for Idiosyncratic Drug-Induced Agranulocytosis.
Int J Mol Sci
; 24(2)2023 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674761
5.
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective.
Chem Res Toxicol
; 35(10): 1649-1654, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35687011
6.
Liver Injury Caused by Green Tea Extract in PD-1-/- Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury.
Chem Res Toxicol
; 34(3): 849-856, 2021 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617238
7.
Severe cutaneous adverse reaction associated with antiseizure medications: Diagnosis, management, and prevention.
Epilepsy Behav
; 117: 107844, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33639435
8.
Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges.
Int J Mol Sci
; 22(6)2021 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33799477
9.
Best practices for detection, assessment and management of suspected immune-mediated liver injury caused by immune checkpoint inhibitors during drug development.
J Autoimmun
; 114: 102514, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32768244
10.
The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity Reactions.
Drug Metab Dispos
; 47(10): 1093-1096, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31324698
11.
Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury.
Chem Res Toxicol
; 32(7): 1423-1431, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31251588
12.
Do In Vitro Assays Predict Drug Candidate Idiosyncratic Drug-Induced Liver Injury Risk?
Drug Metab Dispos
; 46(11): 1658-1669, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021844
13.
The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury.
Chem Res Toxicol
; 31(8): 739-744, 2018 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29938495
14.
Dose-dependent acute liver injury with hypersensitivity features in humans due to a novel microsomal prostaglandin E synthase 1 inhibitor.
Br J Clin Pharmacol
; 84(1): 179-188, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28865237
15.
Nevirapine-induced liver lipid-SER inclusions and other ultrastructural aberrations.
Ultrastruct Pathol
; 42(2): 108-115, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29424579
16.
Supernatant from Hepatocyte Cultures with Drugs That Cause Idiosyncratic Liver Injury Activates Macrophage Inflammasomes.
Chem Res Toxicol
; 30(6): 1327-1332, 2017 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28525267
17.
How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction.
Chem Res Toxicol
; 30(1): 295-314, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27775332
18.
Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients.
Hepatology
; 61(4): 1332-42, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25283142
19.
Protein Targets of Isoniazid-Reactive Metabolites in Mouse Liver in Vivo.
Chem Res Toxicol
; 29(6): 1064-72, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097313
20.
Mechanism of isoniazid-induced hepatotoxicity: then and now.
Br J Clin Pharmacol
; 81(6): 1030-6, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26773235