Intra-articular therapy of experimental arthritis with a derivative of triamcinolone acetonide incorporated in liposomes.

Triamcinolone acetonide-21-palmitate was synthesized and incorporated into liposomes for intra-articular treatment of an experimentally-induced arthritis in the knee joints of rabbits. The liposomal formulation was more efficient than free triamcinolone acetonide in solution in suppressing the arthritis. Using radioactive tracers, it was found that triamcinolone acetonide-21-palmitate incorporated into liposomes was retained in the articular cavity, together with the liposomal lipids, for a much longer period than free triamcinolone acetonide, and this correlated with its anti-inflammatory effect.

[Chronology of the postnatal ossification of the shoulder and elbow joints in the Siamese cat (Felis catus L.)]. / Cronología de osificación postnatal de las articulaciones del hombro y codo en el gato siamés (Felis catus L.).

A study was done by radiological techniques to show the chronology of ossification of the shoulder and cubit joints in the Siam cat, from birth up to the 25th week of postnatal development. For this experiment we used 40 little cats (19 males and 21 females) belonging to 11 litters subjected to different controls: pattern race, healthy, feeding, growing up and radioactivity. The time of the appearance and the evolution of the ossification centers is determined as well as the phenomenon of fusion during this time. The postnatal ossification from both joints of the Siam cat is compared with that of the common cat.

Differences in fibre population in dog muscles of different functional purpose.

Samples were taken from particular sites of the tibialis cranialis (extensor), flexor digitalis medialis (flexor) and pectineus (adductor) muscles of 27 dogs of different breeds--German shepherd, Spanish greyhound, Spanish mastiff and Iberian hound. Samples, which were taken from right and left limbs, were subjected to histochemical analysis using ATPase (pH 9.4, 4.6 and 4.2) and NADH-tr. Fibre population was assessed using an IBAS-2 Kontron image analyser.

Muscle fibre morphometry in three dog muscles of different functional purpose in different breeds.

Following a study of fibre population fibre size was determined in three muscles of different functional purpose in four breeds of dog with different locomotory capacities. Samples were taken from specific sites in the tibialis cranialis (extensor), flexor digitalis medialis (flexor) and pectineus (adductor) muscles of 27 dogs of four different breeds--German shepherd, Spanish greyhound, Spanish mastiff and Iberian hound--. Samples were subjected to histochemical analysis using ATPase (pH 9.4) and fibre size was assessed using an IBAS-2 Kontron image analyser.

[Chronology of the postnatal ossification of the thoracic limb in the Siamese cat (Felis catus L.)]. / Cronología de osificación postnatal del autópodo torácico en el gato Siamés (Felis catus L.).

A study was done by radiological techniques to show the chronology of ossification of the thoracic autopodo of the Siam cat from birth up to the 25th week of postnatal development. For this experiment we used 40 little cats (19 males and 21 females) belonging to 11 litters subjected to different controls: pattern race, healthy, feeding, grow up and radioactivity. The time of the appearance and evolution of the centres that form the basipodo, metapodo and acropodo of the thoracic limb is determined. Likewise it is analyzed the phenomenon of fusion during that time to define the main ossification sequence in the carpo. The aspects of the postnatal ossification of the thoracic autopodo in the Siam cat are compared with the literature of different authors about the common cat.