Detalhe da pesquisa
1.
Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis.
Genes Dev
; 35(15-16): 1079-1092, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34266888
2.
Aneuploidy in Cancer and Aging.
Annu Rev Genet
; 50: 45-66, 2016 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27893964
3.
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
Nature
; 562(7728): 578-582, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232451
4.
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
Mol Cell
; 62(2): 272-283, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27151442
5.
Chronic social and psychological stress impact select neuropathologies in the PS19 mouse model of tauopathy.
Psychosom Med
; 2023 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37910129
6.
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.
Cell
; 133(1): 103-15, 2008 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18394993
7.
Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.
Mol Cell
; 60(1): 21-34, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26387737
8.
E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.
Hepatology
; 73(1): 303-317, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32259305
9.
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Nature
; 530(7589): 184-9, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26840489
10.
Pak2 kinase promotes cellular senescence and organismal aging.
Proc Natl Acad Sci U S A
; 116(27): 13311-13319, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209047
11.
Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.
Hum Mol Genet
; 28(11): 1822-1836, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30668728
12.
Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.
Gastroenterology
; 157(1): 210-226.e12, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30878468
13.
The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.
Circ Res
; 122(12): 1648-1660, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545368
14.
The role of senescent cells in ageing.
Nature
; 509(7501): 439-46, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848057
15.
Inhibition of 'jumping genes' promotes healthy ageing.
Nature
; 566(7742): 46-48, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728507
16.
Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.
Proc Natl Acad Sci U S A
; 114(15): 3933-3938, 2017 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348210
17.
Senescent cells in the development of cardiometabolic disease.
Curr Opin Lipidol
; 30(3): 177-185, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30913069
18.
FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements.
J Lipid Res
; 60(9): 1547-1561, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253637
19.
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Gastroenterology
; 154(8): 2209-2221.e14, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454793
20.
Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.
Nucleic Acids Res
; 45(8): 4564-4576, 2017 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199696