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1.
Geophys Res Lett ; 49(20): e2022GL098274, 2022 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-36582354

RESUMO

There is a lack of satellite-based aerosol retrievals in the vicinity of low-topped clouds, mainly because reflectance from aerosols is overwhelmed by three-dimensional cloud radiative effects. To account for cloud radiative effects on reflectance observations, we develop a Convolutional Neural Network and retrieve aerosol optical depth (AOD) with 100-500 m horizontal resolution for all cloud-free regions regardless of their distances to clouds. The retrieval uncertainty is 0.01 + 5%AOD, and the mean bias is approximately -2%. In an application to satellite observations, aerosol hygroscopic growth due to humidification near clouds enhances AOD by 100% in regions within 1 km of cloud edges. The humidification effect leads to an overall 55% increase in the clear-sky aerosol direct radiative effect. Although this increase is based on a case study, it highlights the importance of aerosol retrievals in near-cloud regions, and the need to incorporate the humidification effect in radiative forcing estimates.

2.
Water Resour Res ; 58(8): e2022WR031940, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36249278

RESUMO

Data assimilation (DA) is a powerful tool to optimally combine uncertain model simulations and observations. Among DA techniques, the particle filter (PF) has gained attention for its capacity to deal with nonlinear systems and for its relaxation of the Gaussian assumption. However, the PF may suffer from degeneracy and sample impoverishment. In this study, we propose an innovative approach, based on a tempered particle filter (TPF), aiming at mitigating PFs issues, thus extending over time the assimilation benefits. Probabilistic flood maps derived from synthetic aperture radar data are assimilated into a flood forecasting model through an iterative process including a particle mutation in order to keep diversity within the ensemble. Results show an improvement of the model forecasts accuracy, with respect to the Open Loop: on average the root mean square error (RMSE) of water levels decrease by 80% at the assimilation time and by 60% 2 days after the assimilation. A comparison with the Sequential Importance Sampling (SIS) is carried out showing that although SIS performances are generally comparable to the TPF ones at the assimilation time, they tend to decrease more quickly. For instance, on average TPF-based RMSE are 20% lower compared to the SIS-based ones 2 days after the assimilation. The application of the TPF determines higher critical success index values compared to the SIS. On average the increase in performances lasts for almost 3 days after the assimilation. Our study provides evidence that the application of the variant of the TPF enables more persistent benefits compared to the SIS.

3.
Geophys Res Lett ; 48(2): e2020GL091236, 2021 Jan 28.
Artigo em Inglês | MEDLINE | ID: mdl-33678926

RESUMO

We introduce new parameterizations for autoconversion and accretion rates that greatly improve representation of the growth processes of warm rain. The new parameterizations capitalize on machine-learning and optimization techniques and are constrained by in situ cloud probe measurements from the recent Atmospheric Radiation Measurement Program field campaign at Azores. The uncertainty in the new estimates of autoconversion and accretion rates is about 15% and 5%, respectively, outperforming existing parameterizations. Our results confirm that cloud and drizzle water content are the most important factors for determining accretion rates. However, for autoconversion, in addition to cloud water content and droplet number concentration, we discovered a key role of drizzle number concentration that is missing in current parameterizations. The robust relation between autoconversion rate and drizzle number concentration is surprising but real, and furthermore supported by theory. Thus, drizzle number concentration should be considered in parameterizations for improved representation of the autoconversion process.

4.
Chaos ; 31(12): 123128, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34972351

RESUMO

Many frameworks exist to infer cause and effect relations in complex nonlinear systems, but a complete theory is lacking. A new framework is presented that is fully nonlinear, provides a complete information theoretic disentanglement of causal processes, allows for nonlinear interactions between causes, identifies the causal strength of missing or unknown processes, and can analyze systems that cannot be represented on directed acyclic graphs. The basic building blocks are information theoretic measures such as (conditional) mutual information and a new concept called certainty that monotonically increases with the information available about the target process. The framework is presented in detail and compared with other existing frameworks, and the treatment of confounders is discussed. While there are systems with structures that the framework cannot disentangle, it is argued that any causal framework that is based on integrated quantities will miss out potentially important information of the underlying probability density functions. The framework is tested on several highly simplified stochastic processes to demonstrate how blocking and gateways are handled and on the chaotic Lorentz 1963 system. We show that the framework provides information on the local dynamics but also reveals information on the larger scale structure of the underlying attractor. Furthermore, by applying it to real observations related to the El-Nino-Southern-Oscillation system, we demonstrate its power and advantage over other methodologies.


Assuntos
Causalidade , Processos Estocásticos
5.
Space Weather ; 15(11): 1490-1510, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-29398983

RESUMO

Data assimilation (DA) is used extensively in numerical weather prediction (NWP) to improve forecast skill. Indeed, improvements in forecast skill in NWP models over the past 30 years have directly coincided with improvements in DA schemes. At present, due to data availability and technical challenges, DA is underused in space weather applications, particularly for solar wind prediction. This paper investigates the potential of advanced DA methods currently used in operational NWP centers to improve solar wind prediction. To develop the technical capability, as well as quantify the potential benefit, twin experiments are conducted to assess the performance of the Local Ensemble Transform Kalman Filter (LETKF) in the solar wind model ENLIL. Boundary conditions are provided by the Wang-Sheeley-Arge coronal model and synthetic observations of density, temperature, and momentum generated every 4.5 h at 0.6 AU. While in situ spacecraft observations are unlikely to be routinely available at 0.6 AU, these techniques can be applied to remote sensing of the solar wind, such as with Heliospheric Imagers or interplanetary scintillation. The LETKF can be seen to improve the state at the observation location and advect that improvement toward the Earth, leading to an improvement in forecast skill in near-Earth space for both the observed and unobserved variables. However, sharp gradients caused by the analysis of a single observation in space resulted in artificial wavelike structures being advected toward Earth. This paper is the first attempt to apply DA to solar wind prediction and provides the first in-depth analysis of the challenges and potential solutions.

6.
Philos Trans A Math Phys Eng Sci ; 373(2034)2015 Feb 13.
Artigo em Inglês | MEDLINE | ID: mdl-25548263

RESUMO

The analysis of symbolic dynamics applied to physiological time series retrieves dynamical properties of the underlying regulation which are robust against the symbolic transformation. In this study, three different transformations to produce a symbolic series were applied to fetal RR interval series to test whether they reflect individual changes of fetal heart rate variability in the course of pregnancy. Each transformation was applied to 215 heartbeat datasets obtained from 11 fetuses during the second and the third trimester of pregnancy (at least 10 datasets per fetus, median 17). In the symbolic series, the occurrence of symbolic sequences of length 3 was categorized according to the amount of variations in the sequence: no variation of the symbols, one variation, two variations. Linear regression with respect to gestational age showed that the individual course during pregnancy performed best using a binary transformation reflecting whether the RR interval differences are below or above a threshold. The median goodness of fit of the individual regression lines was 0.73 and also the variability among the individual slopes was low. Other transformations to symbolic dynamics performed worse but were still able to reflect the individual progress of fetal cardiovascular regulation.

7.
Ergonomics ; 58(8): 1347-64, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25693035

RESUMO

Technological developments have led to increased visual fidelity of driving simulators. However, simplified visuals have potential advantages, such as improved experimental control, reduced simulator discomfort and increased generalisability of results. In this driving simulator study, we evaluated the effects of visual fidelity on driving performance, gaze behaviour and subjective discomfort ratings. Twenty-four participants drove a track with 90° corners in (1) a high fidelity, textured environment, (2) a medium fidelity, non-textured environment without scenery objects and (3) a low-fidelity monochrome environment that only showed lane markers. The high fidelity level resulted in higher steering activity on straight road segments, higher driving speeds and higher gaze variance than the lower fidelity levels. No differences were found between the two lower fidelity levels. In conclusion, textures and objects were found to affect steering activity and driving performance; however, gaze behaviour during curve negotiation and self-reported simulator discomfort were unaffected. PRACTITIONER SUMMARY: In a driving simulator study, three levels of visual fidelity were evaluated. The results indicate that the highest fidelity level, characterised by a textured environment, resulted in higher steering activity, higher driving speeds and higher variance of horizontal gaze than the two lower fidelity levels without textures.


Assuntos
Condução de Veículo/psicologia , Movimentos Oculares , Satisfação Pessoal , Percepção Visual , Adulto , Simulação por Computador , Feminino , Humanos , Masculino , Desempenho Psicomotor , Adulto Jovem
8.
J Geophys Res Atmos ; 127(8): e2021JD036079, 2022 Apr 27.
Artigo em Inglês | MEDLINE | ID: mdl-35865320

RESUMO

Hurricane Patricia (2015) over the eastern Pacific was a record-breaking tropical cyclone (TC) under a very favorable environment during its rapid intensification (RI) period, which makes it an optimal real case for studying RI dynamics and predictability. In this study, we performed ensemble Kalman filter analyses at Patricia's early development stage using both traditional observations and the Office of Naval Research Tropical Cyclone Intensity (TCI) field campaign data. It is shown that assimilating the inner-core TCI observations produces a stronger initial vortex and significantly improves the prediction of RI. Analysis of observation sensitivity experiments shows that the deep-layer dropsonde observations have high impact on both the primary and secondary circulations for the entire troposphere while the radar observations have the most impact on the primary circulations near aircraft flight level. A wide range of intensification scenarios are obtained through two sets of ensemble forecasts initialized with and without assimilating the TCI data prior to the RI onset. Verification of the ensemble forecasts against the TCI observations during the RI period shows that forecast errors toward later stages can originate from two different error sources at early stages of the vortex structure: One is a timing error from a delayed vortex development such that the TC evolution is the same but shifted in time; the other is due to a totally different storm such that there is no moment in time the simulated storm can obtain a correct TC structure.

9.
J Geophys Res Oceans ; 127(3): e2021JC018025, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35865796

RESUMO

Surface freshening through precipitation can act to stably stratify the upper ocean, forming a rain layer (RL). RLs inhibit subsurface vertical mixing, isolating deeper ocean layers from the atmosphere. This process has been studied using observations and idealized simulations. The present ocean modeling study builds upon this body of work by incorporating spatially resolved and realistic atmospheric forcing. Fine-scale observations of the upper ocean collected during the Dynamics of the Madden-Julian Oscillation field campaign are used to verify the General Ocean Turbulence Model (GOTM). Spatiotemporal characteristics of equatorial Indian Ocean RLs are then investigated by forcing a 2D array of GOTM columns with realistic and well-resolved output from an existing regional atmospheric simulation. RL influence on the ocean-atmosphere system is evaluated through analysis of RL-induced modification to surface fluxes and sea surface temperature (SST). This analysis demonstrates that RLs cool the ocean surface on time scales longer than the associated precipitation event. A second simulation with identical atmospheric forcing to that in the first, but with rainfall set to zero, is performed to investigate the role of rain temperature and salinity stratification in maintaining cold SST anomalies within RLs. Approximately one third, or 0.1°C, of the SST reduction within RLs can be attributed to rain effects, while the remainder is attributed to changes in atmospheric temperature and humidity. The prolonged RL-induced SST anomalies enhance SST gradients that have been shown to favor the initiation of atmospheric convection. These findings encourage continued research of RL feedbacks to the atmosphere.

10.
Ann Noninvasive Electrocardiol ; 16(4): 379-87, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-22008494

RESUMO

BACKGROUND: Pathological changes in cardiac electrophysiology have been investigated in coronary artery disease using magnetocardiography. Aim of this work was to examine the structure of cardiac magnetic field maps (MFM) during ventricular depolarization and repolarization in patients with acute ST elevation myocardial infarction (STEMI). METHODS: Magnetocardiograms were recorded in 39 healthy subjects and 97 patients who had been successfully revascularized after STEMI. Using the Karhunen-Loeve transform, 12 eigenmaps were constructed for six intervals within the QT interval of each subject's signal-averaged data. The relative information content of the eigenmaps was compared between STEMI patients and healthy subjects. RESULTS: Relative nondipolar content was between 0.03% and 0.52% higher in the STEMI group, (P < 0.001 for the repolarization intervals). Information content of the first dipolar eigenmap in the STEMI group was reduced by 2.6%-11.7% (P < 0.001 for the repolarization intervals). STT interval was best able to discriminate between groups: area-under-the-curve for nondipolar content was 85.8% (P < 0.001), for the first eigenmap 91.7% (P < 0.001). Severity of infarction was reflected in lower STT interval map 1 content for patients with anterior versus posterior infarction (83%± 11% vs. 87%± 10%, P < 0.05), with wall motion disturbances (84%± 11% vs. 92%± 7%, P < 0.001) and with microvascular obstruction (81%± 12% vs. 87%± 10%, P < 0.05). Regression analysis showed that patients with lower ejection fraction tended to have less information content (P < 0.001). CONCLUSION: STEMI is associated with a loss of spatial coherence during repolarization, as quantified by principal component analysis of cardiac MFM.


Assuntos
Campos Magnéticos , Magnetocardiografia , Infarto do Miocárdio/patologia , Miocárdio/patologia , Adulto , Área Sob a Curva , Feminino , Humanos , Imagem Cinética por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Análise de Componente Principal , Curva ROC
11.
Q J R Meteorol Soc ; 147(734): 573-588, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33867588

RESUMO

Data assimilation is often performed under the perfect model assumption. Although there is an increasing amount of research accounting for model errors in data assimilation, the impact of an incorrect specification of the model errors on the data assimilation results has not been thoroughly assessed. We investigate the effect that an inaccurate time correlation in the model error description can have on data assimilation results, deriving analytical results using a Kalman Smoother for a one-dimensional system. The analytical results are evaluated numerically to generate useful illustrations. For a higher-dimensional system, we use an ensemble Kalman Smoother. Strong dependence on observation density is found. For a single observation at the end of the window, the posterior variance is a concave function of the guessed decorrelation time-scale used in the data assimilation process. This is due to an increasing prior variance with that time-scale, combined with a decreasing tendency from larger observation influence. With an increasing number of observations, the posterior variance decreases with increasing guessed decorrelation time-scale because the prior variance effect becomes less important. On the other hand, the posterior mean-square error has a convex shape as a function of the guessed time-scale with a minimum where the guessed time-scale is equal to the real decorrelation time-scale. With more observations, the impact of the difference between two decorrelation time-scales on the posterior mean-square error reduces. Furthermore, we show that the correct model error decorrelation time-scale can be estimated over several time windows using state augmentation in the ensemble Kalman Smoother. Since model errors are significant and significantly time correlated in real geophysical systems such as the atmosphere, this contribution opens up a next step in improving prediction of these systems.

12.
Q J R Meteorol Soc ; 147(737): 2352-2374, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34262229

RESUMO

A novel particle filter proposed recently, the particle flow filter (PFF), avoids the long-existing weight degeneracy problem in particle filters and, therefore, has great potential to be applied in high-dimensional systems. The PFF adopts the idea of a particle flow, which sequentially pushes the particles from the prior to the posterior distribution, without changing the weight of each particle. The essence of the PFF is that it assumes the particle flow is embedded in a reproducing kernel Hilbert space, so that a practical solution for the particle flow is obtained. The particle flow is independent of the choice of kernel in the limit of an infinite number of particles. Given a finite number of particles, we have found that a scalar kernel fails in high-dimensional and sparsely observed settings. A new matrix-valued kernel is proposed that prevents the collapse of the marginal distribution of observed variables in a high-dimensional system. The performance of the PFF is tested and compared with a well-tuned local ensemble transform Kalman filter (LETKF) using the 1,000-dimensional Lorenz 96 model. It is shown that the PFF is comparable to the LETKF for linear observations, except that explicit covariance inflation is not necessary for the PFF. For nonlinear observations, the PFF outperforms LETKF and is able to capture the multimodal likelihood behavior, demonstrating that the PFF is a viable path to fully nonlinear geophysical data assimilation.

13.
Biomed Tech (Berl) ; 54(1): 29-37, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19182871

RESUMO

Fetal magnetocardiography (fMCG) has been shown to augment fetal ultrasound evaluation for high-risk conditions, but the clinical utility of fMCG depends on the reliability of the cardiac traces reconstructed. We performed a methodological study to examine the influence of gestational age on the properties of the fetal magnetocardiograms extracted with two methods of signal reconstruction: the template matching technique (TMT), which extracts the maternal components from the signal using only temporal information, and independent component analysis (ICA), which separates the fetal signals by using information on the spatial distribution of the mixed source signals in addition to higher order temporal statistics. Efficiency and accuracy were evaluated in terms of fetal beat detection, signal characteristics, and duration of cardiac time intervals (CTIs) on the averaged traces. ICA outperformed TMT with regard to beat detection and signal-to-noise ratio. The timing of the heartbeats and the duration of the CTIs were essentially the same, whereas some alterations in signal morphology were observed in the ICA traces. We conclude that ICA may be useful in early gestation when the signals are noisy, while TMT may be preferred when accurate beat morphology is required for diagnostic purposes.


Assuntos
Algoritmos , Cardiotocografia/métodos , Diagnóstico por Computador/métodos , Idade Gestacional , Frequência Cardíaca Fetal/fisiologia , Magnetocardiografia/métodos , Humanos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
14.
Q J R Meteorol Soc ; 145(723): 2335-2365, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31598012

RESUMO

Particle filters contain the promise of fully nonlinear data assimilation. They have been applied in numerous science areas, including the geosciences, but their application to high-dimensional geoscience systems has been limited due to their inefficiency in high-dimensional systems in standard settings. However, huge progress has been made, and this limitation is disappearing fast due to recent developments in proposal densities, the use of ideas from (optimal) transportation, the use of localization and intelligent adaptive resampling strategies. Furthermore, powerful hybrids between particle filters and ensemble Kalman filters and variational methods have been developed. We present a state-of-the-art discussion of present efforts of developing particle filters for high-dimensional nonlinear geoscience state-estimation problems, with an emphasis on atmospheric and oceanic applications, including many new ideas, derivations and unifications, highlighting hidden connections, including pseudo-code, and generating a valuable tool and guide for the community. Initial experiments show that particle filters can be competitive with present-day methods for numerical weather prediction, suggesting that they will become mainstream soon.

15.
Physiol Meas ; 40(6): 064002, 2019 07 03.
Artigo em Inglês | MEDLINE | ID: mdl-31071684

RESUMO

OBJECTIVE: In fetal diagnosis the myriad and diversity of heart rate variability (HRV) indices prevents a comparable routine evaluation of disturbances in fetal development and well-being. The work aims at the extraction of a small set of HRV key indices that could help to establish a universal, overarching tool to screen for any disturbance. APPROACH: HRV indices were organized in categories of short-term (prefix s) and long-term (prefix l) amplitude fluctuations (AMP), complexity (COMP), and patterns (PATTERN) and common representatives for each category were extracted. This procedure was done with respect to the diagnostic value in the evaluation of the maturation age throughout the second and complete third trimester of pregnancy as well as to potential differences associated with maternal life-style factors (physical exercise, smoking), nutrient intervention (docosahexaenoic acid (DHA) supplementation), and complications of pregnancy (gestational diabetes mellitus (GDM), intra-uterine growth restriction (IUGR)). MAIN RESULTS: We found a comprehensive minimal set that includes [lAMP: short term variation (STV), initially introduced in cardiotocography, sAMP: heart rate increase across one interbeat interval of phase rectified averaged signal - acceleration capacity (ACst1), lCOMP: scale 4 multi-scale entropy (MSE4), PATTERN: skewness] for the maturation age prediction, and partly overlapping [lAMP: STV, sAMP: ACst1, sCOMP: Lempel Ziv complexity (LZC)] for the discrimination of the deviations. SIGNIFICANCE: The minimal set of category-based HRV representatives allows for a screening of fetal development and well-being. These results are an important step towards a universal and comparable diagnostic tool for the early identification of developmental disturbances. Novelty & Significance Fetal development and its disturbances have been reported to be associated with a multiplicity of HRV indices. Furthermore, these HRV indices change with maturation. We propose the abstraction of HRV categories defined by short- and long-term fluctuation amplitude, complexity, and pattern indices that cover all relevant aspects of maturational age, behavioral influences and a series of pathological disturbances. The study data are provided by multiple centers. Our approach is an important step towards the goal of a standardized diagnostic tool for early identification of fetal developmental disturbances with respect to the reduction of serious complications in the later life.


Assuntos
Biomarcadores/metabolismo , Desenvolvimento Fetal/fisiologia , Frequência Cardíaca Fetal/fisiologia , Área Sob a Curva , Feminino , Idade Gestacional , Humanos , Modelos Lineares , Gravidez
16.
Phys Med Biol ; 53(9): 2291-301, 2008 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-18401064

RESUMO

We compared the stability and discriminatory power of different methods of determining cardiac magnetic field map (MFM) orientation within the context of coronary artery disease (CAD). In 27 healthy subjects and 24 CAD patients, multichannel magnetocardiograms were registered at rest. MFM orientation was determined during QT interval using: (a) locations of the positive and negative centres-of-gravity, (b) locations of the field extrema and (c) the direction of the maximum field gradient. Deviation from normal orientation quantified the ability of each approach to discriminate between healthy and CAD subjects. Although the course of orientation was similar for all methods, receiver operating characteristic analysis showed the best discrimination of CAD patients for the centre-of-gravity approach (area-under-the-curve = 86%), followed by the gradient (84%) and extrema (76%) methods. Consideration of methodological and discriminatory advantages with respect to noninvasive diagnosis of CAD suggests that the centres-of-gravity method is the most suited one.


Assuntos
Doença da Artéria Coronariana/diagnóstico , Campos Eletromagnéticos , Ventrículos do Coração/patologia , Adulto , Idoso , Área Sob a Curva , Estudos de Casos e Controles , Doença da Artéria Coronariana/patologia , Feminino , Humanos , Magnetoencefalografia/instrumentação , Magnetoencefalografia/métodos , Masculino , Pessoa de Meia-Idade , Curva ROC , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
17.
Pacing Clin Electrophysiol ; 31(9): 1213-7, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18834476

RESUMO

We present a case of supraventricular tachycardia affecting one fetus in a twin pregnancy. Before and after treatment with flecainide and cardioversion, we examined conduction times and heart rate variability (HRV) in both twins on the basis of magnetocardiography. Cardiac conduction times increased in both fetuses but HRV showed opposing effects with a number of HRV measures. This case demonstrates that magnetocardiography not only enables identification of fetal arrhythmia, but also permits the investigation of the effects of antiarrhythmic treatment on the conductive system as well as on interaction with the autonomic nervous system.


Assuntos
Antiarrítmicos/uso terapêutico , Doenças em Gêmeos/tratamento farmacológico , Doenças Fetais/tratamento farmacológico , Flecainida/uso terapêutico , Cuidado Pré-Natal/métodos , Adulto , Doenças em Gêmeos/diagnóstico , Feminino , Doenças Fetais/diagnóstico , Humanos , Gravidez , Gravidez Múltipla , Resultado do Tratamento , Gêmeos
18.
Fetal Diagn Ther ; 24(4): 327-30, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18836269

RESUMO

BACKGROUND: Magnetocardiography and M-mode fetal echocardiography are non-invasive techniques capable of identifying fetal arrhythmias. The STAN-fetal scalp electrode system can record the fetal echocardiogram in labor. CASE: A patient was admitted to hospital with preterm contractions and cervical insufficiency at 28 weeks of gestation. After treatment with a beta-sympathomimetic drug (Partusisten) one fetus developed supraventricular tachycardia. After terminating the Partusisten medication, there was no effect on the fetal arrhythmia and flecainide therapy was initiated. Maintenance dosages controlled the condition thereafter. Cardiac time intervals of a fetus in labor can be presented, which did not change significantly throughout the first stage of labor. CONCLUSION: Flecainide is an effective therapy for supraventricular tachycardias in a twin pregnancy. Analyzing the cardiac time intervals during pregnancy can improve perinatal outcome.


Assuntos
Antiarrítmicos/administração & dosagem , Doenças Fetais/diagnóstico , Doenças Fetais/tratamento farmacológico , Flecainida/administração & dosagem , Taquicardia Supraventricular/diagnóstico , Taquicardia Supraventricular/tratamento farmacológico , Agonistas Adrenérgicos beta/administração & dosagem , Agonistas Adrenérgicos beta/efeitos adversos , Adulto , Ecocardiografia , Feminino , Fenoterol/administração & dosagem , Fenoterol/efeitos adversos , Doenças Fetais/induzido quimicamente , Humanos , Recém-Nascido , Masculino , Trabalho de Parto Prematuro/tratamento farmacológico , Gravidez , Resultado da Gravidez , Taquicardia Supraventricular/induzido quimicamente , Gêmeos , Ultrassonografia Pré-Natal
19.
Q J R Meteorol Soc ; 144(717): 2650-2665, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30774157

RESUMO

Data assimilation is often performed in a perfect-model scenario, where only errors in initial conditions and observations are considered. Errors in model equations are increasingly being included, but typically using rather adhoc approximations with limited understanding of how these approximations affect the solution and how these approximations interfere with approximations inherent in finite-size ensembles. We provide the first systematic evaluation of the influence of approximations to model errors within a time window of weak-constraint ensemble smoothers. In particular, we study the effects of prescribing temporal correlations in the model errors incorrectly in a Kalman smoother, and in interaction with finite-ensemble-size effects in an ensemble Kalman smoother. For the Kalman smoother we find that an incorrect correlation time-scale for additive model errors can have substantial negative effects on the solutions, and we find that overestimating of the correlation time-scale leads to worse results than underestimating. In the ensemble Kalman smoother case, the resulting ensemble-based space-time gain can be written as the true gain multiplied by two factors, a linear factor containing the errors due to both time-correlation errors and finite ensemble effects, and a nonlinear factor related to the inverse part of the gain. Assuming that both errors are relatively small, we are able to disentangle the contributions from the different approximations. The analysis mean is affected by the time-correlation errors, but also substantially by finite-ensemble effects, which was unexpected. The analysis covariance is affected by both time-correlation errors and an in-breeding term. This first thorough analysis of the influence of time-correlation errors and finite-ensemble-size errors on weak-constraint ensemble smoothers will aid further development of these methods and help to make them robust for e.g. numerical weather prediction.

20.
Q J R Meteorol Soc ; 144(713): 1310-1320, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31031422

RESUMO

A method is presented for estimating the error covariance of the errors in the model equations in observation space. Estimating model errors in this systematic way opens up the possibility to use data assimilation for systematic model improvement at the level of the model equations, which would be a huge step forward. This model error covariance is perhaps the hardest covariance matrix to estimate. It represents how the missing physics and errors in parametrizations manifest themselves at the scales the model can resolve. A new element is that we use an efficient particle filter to avoid the need to estimate the error covariance of the state as well, which most other data assimilation methods do require. Starting from a reasonable first estimate, the method generates new estimates iteratively during the data assimilation run, and the method is shown to converge to the correct model error matrix. We also investigate the influence of the accuracy of the observation error covariance on the estimation of the model error covariance and show that, when the observation errors are known, the model error covariance can be estimated well, but, as expected and perhaps unavoidably, the diagonal elements are estimated too low when the observation errors are estimated too high, and vice versa.

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