Detalhe da pesquisa
1.
Safety, pharmacokinetics, and potential neurological interactions of ivermectin, tafenoquine, and chloroquine in Rhesus macaques.
Antimicrob Agents Chemother
; : e0018124, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38742896
2.
Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.
Antimicrob Agents Chemother
; 66(3): e0182121, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978892
3.
Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660993
4.
Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.
Malar J
; 19(1): 269, 2020 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32711538
5.
Piperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia.
Antimicrob Agents Chemother
; 61(5)2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193647
6.
Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta).
Antimicrob Agents Chemother
; 58(12): 7283-91, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25267666
7.
Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval.
Antimicrob Agents Chemother
; 58(10): 6056-67, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092702
8.
Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.
Antimicrob Agents Chemother
; 56(11): 5484-93, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22869581
9.
Dihydroartemisinin-piperaquine failure in Cambodia.
N Engl J Med
; 371(5): 484-5, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25075853
10.
Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand.
Sci Rep
; 11(1): 13419, 2021 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183715
11.
Prevalence of CYP2D6 Genotypes and Predicted Phenotypes in a Cohort of Cambodians at High Risk for Infections with Plasmodium vivax.
Am J Trop Med Hyg
; 103(2): 756-759, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32394887
12.
Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial.
Open Forum Infect Dis
; 6(9): ofz314, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31660398
13.
Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver.
PLoS One
; 12(2): e0171826, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28182750
14.
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.
Sci Transl Med
; 9(387)2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446690
15.
Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study.
Lancet Infect Dis
; 15(6): 683-91, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25877962
16.
Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open-label randomized trial.
PLoS One
; 9(3): e93138, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24667662
17.
Inhibition of heme peroxidases by melamine.
Enzyme Res
; 2012: 416062, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22852071
18.
Determination of visnagin in rat plasma by liquid chromatography with tandem mass spectrometry and its application to in vivo pharmacokinetic studies.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(7): 653-6, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19188097