Detalhe da pesquisa
1.
The intrinsic substrate specificity of the human tyrosine kinome.
Nature
; 629(8014): 1174-1181, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720073
2.
An atlas of substrate specificities for the human serine/threonine kinome.
Nature
; 613(7945): 759-766, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36631611
3.
Dietary fructose improves intestinal cell survival and nutrient absorption.
Nature
; 597(7875): 263-267, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34408323
4.
Phase and context shape the function of composite oncogenic mutations.
Nature
; 582(7810): 100-103, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461694
5.
A view on drug resistance in cancer.
Nature
; 575(7782): 299-309, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723286
6.
A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: implications for clinical practice.
Oncologist
; 19(5): 453-8, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24710307
7.
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens.
Nat Biotechnol
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38783148
8.
Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes.
Proc Natl Acad Sci U S A
; 107(32): 14176-81, 2010 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660722
9.
A New Wave of PI3Kα Inhibitors.
Cancer Discov
; 13(11): 2313-2315, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37909093
10.
Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations.
Clin Cancer Res
; 29(6): 1125-1136, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36595567
11.
Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells.
bioRxiv
; 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168306
12.
Epinephrine inhibits PI3Kα via the Hippo kinases.
Cell Rep
; 42(12): 113535, 2023 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38060450
13.
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Cancer Cell
; 41(7): 1207-1221.e12, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37327789
14.
Genomic Characterization of De Novo Metastatic Breast Cancer.
Clin Breast Cancer
; 22(2): 98-102, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34949553
15.
At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy.
Nat Rev Clin Oncol
; 19(7): 471-485, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484287
16.
Treating Alpelisib-Induced Hyperglycemia with Very Low Carbohydrate Diets and Sodium-Glucose Co-Transporter 2 Inhibitors: A Case Series.
Integr Cancer Ther
; 20: 15347354211032283, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34259084
17.
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors.
Cancer Discov
; 11(1): 126-141, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33004339
18.
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.
Cancer Discov
; 11(5): 1212-1227, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33372007
19.
Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors.
Nat Cancer
; 1(4): 382-393, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32864625
20.
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.
Science
; 366(6466): 714-723, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699932