Detalhe da pesquisa
1.
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172583
2.
The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer.
Int J Mol Sci
; 24(21)2023 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958596
3.
The multifaceted roles of tumor-associated proteases and harnessing their activity for prodrug activation.
Biol Chem
; 400(8): 965-977, 2019 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30913028
4.
Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment.
Nano Lett
; 18(9): 5401-5410, 2018 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30070485
5.
A role for stefin B (cystatin B) in inflammation and endotoxemia.
J Biol Chem
; 289(46): 31736-31750, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288807
6.
Selective targeting of tumor and stromal cells by a nanocarrier system displaying lipidated cathepsin B inhibitor.
Angew Chem Int Ed Engl
; 53(38): 10077-81, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24975267
7.
Isolating Primary Tumor Cells from the MMTV-PyMT Mouse Model and Their Use in Developing an Orthotopic Mouse Model of Breast Cancer.
Methods Mol Biol
; 2773: 59-65, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236536
8.
Cysteine cathepsins: from structure, function and regulation to new frontiers.
Biochim Biophys Acta
; 1824(1): 68-88, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22024571
9.
The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes.
Biol Chem
; 394(2): 307-16, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23152404
10.
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
Proc Natl Acad Sci U S A
; 107(6): 2497-502, 2010 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133781
11.
A New Cathepsin D Targeting Drug Delivery System Based on Immunoliposomes Functionalized with Lipidated Pepstatin A.
Pharmaceutics
; 15(10)2023 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896224
12.
Computational Indicator Approach for Assessment of Nanotoxicity of Two-Dimensional Nanomaterials.
Nanomaterials (Basel)
; 12(4)2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35214977
13.
Theranostic Applications of an Ultra-Sensitive T1 and T2 Magnetic Resonance Contrast Agent Based on Cobalt Ferrite Spinel Nanoparticles.
Cancers (Basel)
; 14(16)2022 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36011020
14.
A Probody T Cell-Engaging Bispecific Antibody Targeting EGFR and CD3 Inhibits Colon Cancer Growth with Limited Toxicity.
Cancer Res
; 82(22): 4288-4298, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112781
15.
Nonclinical Efficacy and Safety of CX-2029, an Anti-CD71 Probody-Drug Conjugate.
Mol Cancer Ther
; 21(8): 1326-1336, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666803
16.
Praluzatamab Ravtansine, a CD166-Targeting Antibody-Drug Conjugate, in Patients with Advanced Solid Tumors: An Open-Label Phase I/II Trial.
Clin Cancer Res
; 28(10): 2020-2029, 2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165101
17.
Promising approaches in using magnetic nanoparticles in oncology.
Biol Chem
; 392(11): 955-60, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21848508
18.
Analyzing the Role of Proteases in Breast Cancer Progression and Metastasis Using Primary Cells from Transgenic Oncomice.
Methods Mol Biol
; 2294: 275-293, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742409
19.
Novel Ex Vivo Zymography Approach for Assessment of Protease Activity in Tissues with Activatable Antibodies.
Pharmaceutics
; 13(9)2021 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34575469
20.
Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents.
Cancer Immunol Res
; 9(12): 1451-1464, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635485