Detalhe da pesquisa
1.
Adeno-associated virus 8-mediated gene therapy for choroideremia: preclinical studies in in vitro and in vivo models.
J Gene Med
; 16(5-6): 122-30, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962736
2.
Treatment Potential for LCA5-Associated Leber Congenital Amaurosis.
Invest Ophthalmol Vis Sci
; 61(5): 30, 2020 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32428231
3.
Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin.
Exp Eye Res
; 89(6): 905-12, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19682985
4.
Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1-9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons.
Stem Cells Int
; 2019: 7281912, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30800164
5.
Use of induced pluripotent stem cell models to probe the pathogenesis of Choroideremia and to develop a potential treatment.
Stem Cell Res
; 27: 140-150, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414605
6.
Author Correction: An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications.
Sci Rep
; 8(1): 17286, 2018 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30470797
7.
RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function.
Invest Ophthalmol Vis Sci
; 59(12): 5225-5236, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30372751
8.
Silencing the expression of CTRP5/C1QTNF5 and ELOVL4 genes by small interfering RNA.
Adv Exp Med Biol
; 723: 225-33, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22183337
9.
Spatial and temporal expression of MFRP and its interaction with CTRP5.
Invest Ophthalmol Vis Sci
; 47(12): 5514-21, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17122143
10.
CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion.
Invest Ophthalmol Vis Sci
; 47(12): 5505-13, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17122142
11.
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease.
Invest Ophthalmol Vis Sci
; 47(8): 3603-11, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16877435
12.
Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.
Invest Ophthalmol Vis Sci
; 47(10): 4558-68, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17003453
13.
Retinas in a Dish Peek into Inherited Retinal Degeneration.
Cell Stem Cell
; 18(6): 688-689, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27257755
14.
Sequencing arrays for screening multiple genes associated with early-onset human retinal degenerations on a high-throughput platform.
Invest Ophthalmol Vis Sci
; 46(9): 3355-62, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16123440
15.
Stargardt-like macular dystrophy protein ELOVL4 exerts a dominant negative effect by recruiting wild-type protein into aggresomes.
Mol Vis
; 11: 665-76, 2005 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16163264
16.
An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications.
Sci Rep
; 5: 17105, 2015 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26597678
17.
Role of ELOVL4 in fatty acid metabolism.
Adv Exp Med Biol
; 613: 283-90, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18188956
18.
AAV-mediated gene therapy for choroideremia: preclinical studies in personalized models.
PLoS One
; 8(5): e61396, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667438
19.
Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation.
PLoS One
; 6(6): e21193, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21738619
20.
Genetics and molecular pathology of Stargardt-like macular degeneration.
Prog Retin Eye Res
; 29(3): 191-207, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20096366