Assuntos
Ácido Aminolevulínico/análogos & derivados , Doença de Bowen/tratamento farmacológico , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/uso terapêutico , Neoplasias Cutâneas/tratamento farmacológico , Idoso , Ácido Aminolevulínico/uso terapêutico , Biomarcadores Tumorais/metabolismo , Resistencia a Medicamentos Antineoplásicos , Feminino , Humanos , Masculino , Estudos Retrospectivos , Resultado do Tratamento , Células Tumorais CultivadasRESUMO
Pure primary squamous cell carcinoma (SCC) is an extremely rare type of breast tumor. We report one of such cases in a 32-year-old woman, diagnosed by fine-needle aspiration cytology (FNAC). Aspiration smears were characterized by squamous cells, both isolated and in aggregates, at various stages of maturation. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. Pure primary SCC of the breast has a distinctive cytomorphologic appearance, and diagnosis of this tumor by FNAC is possible. For its diagnosis, the exclusion of SCC of local cutaneous structures and metastasis of distant squamous carcinoma are mandatory.
Assuntos
Biópsia por Agulha Fina , Neoplasias da Mama/patologia , Carcinoma de Células Escamosas/patologia , Adulto , Neoplasias da Mama/terapia , Carcinoma de Células Escamosas/terapia , Quimioterapia Adjuvante , Feminino , Humanos , Radioterapia AdjuvanteRESUMO
CLINICAL CASE: Our patient was a 37-year-old male with palpebral mycosis fungoides, the most common T-cell cutaneous lymphoma. He had been treated previously with topical corticosteroids. We treated him with Imiquimod cream (5%) three times a week. DISCUSSION: A clinical improvement was obtained with this drug, so we believe immuno-modulating agents need to be considered in the treatment of palpebral mycosis fungoides, especially because of its capacity of being a reflection of leukaemia.
Assuntos
Aminoquinolinas/uso terapêutico , Antineoplásicos/uso terapêutico , Neoplasias Palpebrais/tratamento farmacológico , Micose Fungoide/tratamento farmacológico , Neoplasias Cutâneas/patologia , Adulto , Neoplasias Palpebrais/patologia , Pálpebras/patologia , Pálpebras/cirurgia , Humanos , Imiquimode , Masculino , Micose Fungoide/patologia , Procedimentos Cirúrgicos Oftalmológicos , Neoplasias Cutâneas/tratamento farmacológico , Resultado do TratamentoRESUMO
The cytologic findings in fine needle aspiration smears and cell blocks from a malignant retroperitoneal paraganglioma with subsequent histologic confirmation are described. The aspirate contained clusters of cells with ill-defined borders, often varied in size, round or oval nuclei and marked anisokaryosis. An unusual feature was the presence of prominent intranuclear vacuoles in some cells. The histologic and ultrastructural findings, as well as the results of histochemical and immunodiagnostic staining, are also presented.
Assuntos
Paraganglioma/patologia , Neoplasias Retroperitoneais/patologia , Adenocarcinoma/patologia , Adenoma de Células das Ilhotas Pancreáticas/patologia , Biópsia por Agulha , Carcinoma Hepatocelular/patologia , Núcleo Celular/patologia , Cromograninas/análise , Diagnóstico Diferencial , Humanos , Imuno-Histoquímica , Neoplasias Hepáticas/patologia , Masculino , Pessoa de Meia-Idade , Paraganglioma/ultraestrutura , Neoplasias Retroperitoneais/ultraestruturaRESUMO
The primary signet-ring cell adenocarcinoma of the bladder is a rare tumor, with great biological aggressivity and bad prognosis. We report a clinical case of a 65 years old patient, starting with bladder irritative symptoms and suffering from advanced disease at the initial diagnosis. We review clinical and etiopathogenic aspects about this entity.
Assuntos
Carcinoma de Células em Anel de Sinete , Neoplasias da Bexiga Urinária , Idoso , Carcinoma de Células em Anel de Sinete/etiologia , Carcinoma de Células em Anel de Sinete/patologia , Humanos , Masculino , Neoplasias da Bexiga Urinária/patologia , Neoplasias da Bexiga Urinária/terapiaRESUMO
To del with a case of Intrascrotal epidermal inclusion cysts, clinical manifest like three scrotal masses. The patient was operated by transcrotally excision and he remains still asymptomatic. About this case and the terminology difficulties, we propose a differential diagnosis between different cystic lesion showed in the scrotum. The bibliography revision was performed by the Medline since 1966 until 1999.
Assuntos
Cisto Epidérmico/patologia , Escroto/patologia , Cisto Epidérmico/diagnóstico por imagem , Doenças dos Genitais Masculinos/diagnóstico por imagem , Doenças dos Genitais Masculinos/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Escroto/diagnóstico por imagem , UltrassonografiaRESUMO
Report of three cases of Wunderlich Syndrome secondary to renal adenocarcinoma, hydronephrosis and non-filar blood dyscrasia, highlighting its uncommon etiology. Brief review of the etiopathogenic, diagnostic and therapeutical aspects, pointing out the relevance of renal ultrasonography and, most specially, abdominal CAT to achieve a definitive diagnosis and to determine the attitude to follow, trying to use conservative surgery whenever possible, although our three cases were treated with nephrectomy.
Assuntos
Hematoma/etiologia , Nefropatias/etiologia , Adenocarcinoma/complicações , Adulto , Idoso , Hematoma/diagnóstico , Hematoma/terapia , Humanos , Hidronefrose/complicações , Nefropatias/diagnóstico , Nefropatias/terapia , Neoplasias Renais/complicações , Masculino , Pessoa de Meia-Idade , Paraproteinemias/complicações , SíndromeRESUMO
Case report of a retroperitoneal benign Schwannoma diagnosed accidentally during ultrasound scanning for a different pathology and treated by surgical exeresis. The diagnostic and therapeutic features of this rare neoplasia are reviewed.
Assuntos
Neurilemoma/diagnóstico , Neoplasias Retroperitoneais/diagnóstico , Feminino , Humanos , Pessoa de Meia-Idade , Músculos PsoasRESUMO
A case is presented of melanoma located at the distal urethra in a 74-year-old patient who underwent local surgery. At present the survival rate is 5 years and local relapse and metastases of one inguinal ganglion has been observed. The different clinical, diagnostic and therapeutic aspects of this neoplasia are discussed.
Assuntos
Melanoma/patologia , Recidiva Local de Neoplasia/patologia , Neoplasias Uretrais/patologia , Idoso , Feminino , Humanos , Metástase Linfática , Melanoma/cirurgia , Recidiva Local de Neoplasia/cirurgia , Prognóstico , Neoplasias Uretrais/cirurgiaRESUMO
Human chromophobe renal cell carcinoma is an infrequent neoplasm, recently descripted (1985). It is very important to separate it from the renal cell carcinoma due to its better prognosis. Presentation of the clinical, radiographic and histological features of two cases of chromophobe renal cell carcinoma, diagnosed and treated in our Centre.
Assuntos
Adenocarcinoma/patologia , Carcinoma de Células Renais/patologia , Neoplasias Renais/patologia , Adenocarcinoma/diagnóstico por imagem , Adulto , Carcinoma de Células Renais/diagnóstico por imagem , Feminino , Humanos , Neoplasias Renais/diagnóstico por imagem , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
We report a case of signet ring-cell adenocarcinoma in augmentation colocystoplasty. We review the current literature about tumours developing in augmentation bladder.
Assuntos
Carcinoma de Células em Anel de Sinete/etiologia , Neoplasias da Bexiga Urinária/etiologia , Derivação Urinária/efeitos adversos , Colo/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Bexiga Urinária/cirurgiaRESUMO
We present a case of a nasosinusal malignant melanoma with a really fulminant evolution, as the patient died two and a half months after the diagnostic biopsy and five months after the initial symptoms. A bibliographic review of these rare tumours is realized, and those data of the world literature we could reach concerning to incidence, clinic features, histopathology, diagnosis, treatment, and prognosis, are analyzed.
Assuntos
Neoplasias do Seio Maxilar/patologia , Melanoma/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias dos Seios Paranasais/patologia , Idoso , Neoplasias da Orelha/secundário , Orelha Externa , Humanos , Neoplasias Pulmonares/secundário , Metástase Linfática , Masculino , Melanoma/secundário , Cavidade Nasal , Neoplasias Nasais/patologia , Couro Cabeludo , Neoplasias Cutâneas/secundárioRESUMO
We present a case of rhinoscleroma that were studied in a spanish patient. The location was nasal and extranasal, appearing in the larynx. The diagnosis was established by the morphological picture. A review is given of the geographical distribution of this disease and the principal diagnostic procedures are outlined with special emphasis ou the most reliable staining methods (PAS, Gram), immunofluorescence, immunoperoxydase reactions and electron microscopic study are discussed.