Detalhe da pesquisa
1.
Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis.
Am J Physiol Cell Physiol
; 326(1): C40-C49, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37955120
2.
The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial.
Blood
; 138(22): 2173-2184, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34086880
3.
Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice.
Metab Brain Dis
; 38(7): 2383-2391, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341855
4.
The protein C activator AB002 rapidly interrupts thrombus development in baboons.
Blood
; 135(9): 689-699, 2020 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31977000
5.
Thrombin generation and activity in multiple sclerosis.
Metab Brain Dis
; 36(3): 407-420, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33411219
6.
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Arterioscler Thromb Vasc Biol
; 39(4): 799-809, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700130
7.
Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.
Metab Brain Dis
; 30(1): 57-65, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24810631
8.
Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.
Am J Physiol Lung Cell Mol Physiol
; 306(6): L508-20, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24381131
9.
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Blood
; 119(20): 4762-8, 2012 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22442348
10.
Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A.
J Immunol
; 188(9): 4558-67, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474022
11.
E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis.
Res Sq
; 2023 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37131631
12.
Muscarinic receptor agonists and antagonists: effects on inflammation and immunity.
Handb Exp Pharmacol
; (208): 403-27, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22222708
13.
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Am J Respir Cell Mol Biol
; 43(4): 487-97, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19915153
14.
Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects.
Am J Physiol Lung Cell Mol Physiol
; 297(2): L340-6, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19465517
15.
Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor.
Am J Physiol Lung Cell Mol Physiol
; 297(2): L228-37, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19447892
16.
Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Blood Adv
; 2(2): 85-88, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29365314
17.
Impact of adiponectin overexpression on allergic airways responses in mice.
J Allergy (Cairo)
; 2013: 349520, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23861690
18.
Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
Transl Stroke Res
; 3(3): 381-9, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23634198
19.
Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice.
PLoS One
; 7(7): e41088, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815927
20.
Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes.
J Leukoc Biol
; 90(5): 923-7, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21807745