The Role of Plantar Fascia Tightness in Hallux Limitus: A Biomechanical Analysis.

Restriction of greater toe dorsiflexion without degeneration of the first metatarsophalangeal joint is defined as hallux limitus. We assume that in hallux limitus the limitation of greater toe dorsiflexion takes place in the terminal stance phase because of massive tightening of the calf and plantar structures. The current study investigated the role of a tight plantar fascial structure in impairing dorsiflexion of the greater toe. For the purpose of the study, 7 lower limbs from Thiel-fixated human cadavers were evaluated. To simulate double-limb standing stance, the tibia and fibula were mounted on a materials testing machine and constantly loaded with 350N. Additionally, the tendons of the specimens were loaded using a custom-made system. The plantar fascia was fixed to a clamp and tensioned using a threaded bar. Four different tensile forces were then applied to the plantar fascia (approximately 100, 200, 300, and 350 N) and the extension of the first toe was measured. The results show a significant positive correlation between the decrease in extension of the hallux and the tension applied to the plantar fascia reaching a maximum mean decrease of 4.2° (117% compared with the untightened situation) for an applied tension of 364N.

Characterization of trabecular bone density with ultra-short echo-time MRI at 1.5, 3.0 and 7.0 T--comparison with micro-computed tomography.

The goal of this study was to test the potential of ultra-short echo-time (UTE) MRI at 1.5, 3.0 and 7.0 T for depiction of trabecular bone structure (of the wrist bones), to evaluate whether T2* relaxation times of bone water and parametric maps of T2* of trabecular bone could be obtained at all three field strengths, and to compare the T2* relaxation times with structural parameters obtained from micro-computed tomography (micro-CT) as a reference standard. Ex vivo carpal bones of six wrists were excised en bloc and underwent MRI at 1.5, 3.0 and 7.0 T in a whole-body MR imager using the head coil. A three-dimensional radial fat-suppressed UTE sequence was applied with subsequent acquisitions, with six different echo times TE of 150, 300, 600, 1200, 3500 and 7000 µs. The T2* relaxation time and pixel-wise computed T2* parametric maps were compared with a micro-computed-tomography reference standard providing trabecular bone structural parameters including porosity (defined as the bone-free fraction within a region of interest), trabecular thickness, trabecular separation, trabecular number and fractal dimension (Dk). T2* relaxation curves and parametric maps could be computed from datasets acquired at all field strengths. Mean T2* relaxation times of trabecular bone were 4580 ± 1040 µs at 1.5 T, 2420 ± 560 µs at 3.0 T and 1220 ± 300 µs at 7.0 T, when averaged over all carpal bones. A positive correlation of T2* with trabecular bone porosity and trabecular separation, and a negative correlation of T2* relaxation time with trabecular thickness, trabecular number and fractal dimension, was detected (p < 0.01 for all field strengths and micro-CT parameters). We conclude that UTE MRI may be useful to characterize the structure of trabecular bone, comparable to micro-CT.

C-arm flat-panel CT arthrography of the wrist and elbow: first experiences in human cadavers.

OBJECTIVE: To determine the optimal intra-articular iodine concentration for C-arm flat-panel computed tomography (FPCT) arthrography using advanced joint phantoms and to evaluate its application in human cadaveric wrists and elbows. Multi-detector (MD) CT served as the standard of reference. MATERIALS AND METHODS: Joint phantoms and 10 human cadaveric wrist and elbow joints were scanned with C-arm FPCT (5-s, 8-s, and 20-s runs) and standard MDCT using different and optimal concentrations of iodinated contrast material. CT numbers of contrast material, tissue, and noise were measured and contrast-to-noise ratios (CNR) calculated for quantitative analysis. Image and depiction of cartilage, bone, and soft tissues were rated. Radiation doses were compared. RESULTS: In FPCT, iodine concentrations positively correlated with CT numbers and noise of contrast material and with radiation dose (r = 0.713-0.996, p < 0.05 each). At an iodine concentration of 45 mg/ml, CNR of cartilage and soft tissues were highest for all FPCT acquisitions and higher than in MDCT. The 20-s FPCT run performed best for image quality and depiction of anatomical structures and was rated overall equal to MDCT (p = 0.857). CONCLUSION: The optimal iodine concentration for C-arm FPCT arthrography in this study is 45 mg/ml, leading to superior CNR and image quality for an optimal FPCT protocol compared with standard MDCT arthrography in human cadaveric joints.

Primary stability and stiffness in ankle arthrodes-crossed screws versus anterior plating.

BACKGROUND: Ankle arthrodesis is commonly used for the treatment of osteoarthritis or failed arthroplasty. Screw fixation is the predominant technique to perform ankle arthrodesis. Due to a considerable frequency of failures research suggests the use of an anatomically shaped anterior double plate system as a reliable method for isolated tibiotalar arthrodesis. The purpose of the present biomechanical study was to compare two groups of ankle fusion constructs - three screw fixation and an anterior double plate system - in terms of primary stability and stiffness. METHODS: Six matched-pairs human cadaveric lower legs (Thiel fixated) were used in this study. One specimen from each pair was randomly assigned to be stabilized with the anterior double plate system and the other with the three-screw technique. The different arthrodesis methods were tested by dorsiflexing the foot until failure of the system, defined as rotation of the talus relative to the tibia in the sagittal plane. Experiments were performed on a universal materials testing machine. The force required to make arthrodesis fail was documented. For calculation of the stiffness, a linear regression was fitted to the force-displacement curve in the linear portion of the curve and its slope taken as the stiffness. RESULTS: For the anatomically shaped double-plate system a mean load of 967N was needed (range from 570N to 1400N) to make arthrodesis fail. The three-screw fixation method resisted a mean load of 190N (range from 100N to 280N) (p=0.005). In terms of stiffness a mean of 56N/mm (range from 35N/mm to 79N/mm) was achieved for the anatomically shaped double-plate system whereas a mean of 10N/mm (range from 6N/mm to 18N/mm) was achieved for the three-screw fixation method (p=0.004). CONCLUSIONS: Our biomechanical data demonstrates that the anterior double-plate system is significantly superior to the three-screw fixation technique for ankle arthrodesis in terms of primary stability and stiffness.

Experimental loss of menisci, cartilage and subchondral bone gradually increases anteroposterior knee laxity.

PURPOSE: Anteroposterior knee stability is a relevant factor for the decision-making process of various surgical procedures. In degenerative joints when the implantation of unicompartimental prostheses or corrective osteotomies of the limb are planned, the integrity of the anteroposterior stability with an intact ACL has been regarded as a necessary prerequisite. We hypothesise that joint degeneration, however, may influence the anteroposterior knee laxity. Therefore, we set out to test this hypothesis simulating a progressively 'degenerated' joint in an experimental cadaveric setting. METHODS: Twelve intact transfemorally resected Thiel-fixated cadaver knee joints were divided into 2 groups for manipulation in the medial or lateral compartment. In each knee, we performed (1) unilateral total meniscectomy; (2) simulation of advanced osteoarthritis, by unilateral total cartilage debridement; (3) simulation of a unilateral tibial impression fracture, by resection of 5 mm of the tibial plateau; (4) transection of the ACL. The KT-1000 arthrometer was used to measure the extent of anteroposterior translation at 30° of knee flexion. RESULTS: The mean value for tibial anteroposterior translation before intervention was 3.2 mm (SD: ± 0.8). The mean translation after each intervention was 4.6 mm (SD: ± 0.9; +44%; n.s.) after meniscectomy, 5.9 mm (SD: ± 1.5; +84%; P < 0.05) after cartilage debridement, 8 mm (SD: ± 1.5; +150%; P < 0.01) after bone debridement, and finally 9.7 mm (SD: ± 2.2; +203%; P < 0.05) after resection of the ACL. There were no significant differences between the medial and lateral compartment. CONCLUSION: In absence of massive osteophytes or capsular shrinkage, rapid loss of meniscus, cartilage and particularly loss of subchondral bone may result in a massive increase in anteroposterior translation, mimicking a tear of the ACL. In such a situation, a false positive impression of a ligamentous injury may arise, and decision making is falsely directed away from totally or partially knee joint-preserving procedures. Therefore, in degenerate joints, clinical evaluation of anteroposterior stability should rather rely on the presence of a firm stop than an overall increased joint translation.

Precision of targeting device for subtalar screw placement.

BACKGROUND: When performing subtalar arthrodesis, proper screw placement is fundamental to provide primary stability and to help ensure bone healing. In inexperienced hands this step can be time-consuming and exposes surgeons and patients to radiation. By means of a targeting device these potential drawbacks and dangers could be reduced. It was hypothesized that a specifically designed targeting device would reduce radiation exposure while improving screw placement when compared with the conventional "free-hand'' method. METHODS: Twenty matched-pairs of cadaveric hindfoot specimens (Thiel fixation) were prepared for the purpose of the study. The specimens were randomly assigned into two groups consisting of 10 specimens each: in Group 1 screw placement was performed with the targeting device and in Group 2 screw placement was performed under fluoroscopic control. Screw placement was radiographically judged to be optimal, suboptimal and poor. An experienced, fellowship-trained foot and ankle surgeon and a resident, who had never done subtalar fusions performed the screw placements. Exposure to radiation was assessed by means of the dose area product given by the fluoroscope. RESULTS: Optimal screw positioning was achieved in both groups in ten out of 20 specimens (Group 1, n=5; Group 2, n=5). Suboptimal screw placement was found in eight cases (Group 1, n=4; Group 2, n=4). There were two failures which occurred in fusions performed by the resident (Group 1, n=1; Group 2, n=1). Exposure to radiation was significantly reduced in Group 1 when compared with Group 2 (4.1cGy* cm2 versus 8.1cGy* cm2; p=0.012). No lesion of neurovascular structures due to aiming device placement occurred in Group 1. CONCLUSION: A target-device for screw-placement did not provide a significant technical advantage but did result in less radiation exposure.

Direct MR arthrography of cadaveric wrists: comparison between MR imaging at 3.0T and 7.0T and gross pathologic inspection.

PURPOSE: To prospectively evaluate the diagnostic accuracy of magnetic resonance (MR) arthrography for the detection of articular cartilage abnormalities at 3.0T and 7.0T in cadaveric wrists. MATERIALS AND METHODS: MR imaging (MRI) was performed in nine cadaveric wrists (four right wrists, five left; mean age, 81.0 ± 9.8 years) after the intraarticular administration of gadoterate-meglumine. A 3.0T and 7.0T MR system, mechanically identical custom-built 8-channel wrist coil arrays and a similar standard MRI protocol, were used. MR images were evaluated for visibility of articular cartilage surfaces, presence of cartilage lesions, and confidence of diagnosis by two independent radiologists. Open pathologic inspection served as reference standard. Sensitivity, specificity, negative predictive values (NPV) and positive predictive values (PPV), and accuracy (ACC) were calculated. Wilcoxon signed rank test was used to assess differences in the diagnostic performance. RESULTS: Visibility of articular cartilage surfaces was significantly better at 3.0T than at 7.0T (P < 0.001). Mean sensitivity, specificity, NPV, PPV, ACC for both readers were 63%, 90%, 85%, 76%, 82% at 3.0T, respectively, and 52%, 91%, 82%, 75%, 79% at 7.0T. The difference between 3.0T and 7.0T was not significant for reader 1 (P = 0.51), but was significant for reader 2 (P = 0.01). The level of confidence was significantly higher at 3.0T than at 7.0T for both readers (P = 0.004; P = 0.03). CONCLUSION: MR arthrography of the wrist at 7.0T is still limited by the lack of commercially available radiofrequency coils and limited experience in sequence optimization, resulting in a significantly lower visibility of anatomy, lower diagnostic accuracy, and level of confidence in judging cartilage lesions compared to 3.0T.

Percutaneous lateral ankle stabilization: an anatomical investigation.

BACKGROUND: The current study investigated the topographic anatomy of the percutaneous anatomical lateral ankle stabilization in relation to the neurovascular hindfoot structures. The study should serve as an aid for performance of this new minimally invasive technique. MATERIALS AND METHODS: Eleven cadaver specimens were dissected exposing the nerves, vessels, ligaments and tendons. The portals and transosseous tunnels were performed with Kirschner wires. All distances of the Kirschner wires and the neurovascular structures were measured with reference to clearly identifiable bony landmarks. RESULTS: On the medial side the average distance of the Kirschner wire to the medial calcaneal branch of the tibial nerve was found to be 7 mm (SD±4). The medial calcaneal branch was hit twice by the transosseous Kirschner wire. On the lateral side the mean distance of the fibular exit point of the Kirschner wire to the sural nerve was 13 mm (SD±4). The closest distance of the superficial peroneal nerve to the footprint of the ATFL averaged 11.5 mm (SD±3) and its anterior location in relation to the tip of the fibula was 28 mm (SD±8). The posterior tibial artery was found at a mean distance of 41 mm from the perforating Kirschner wire (SD±6). CONCLUSION: The current study introduced a novel percutaneous approach to treat chronic ankle instability that had minimal risk to neurovascular structures in a cadaver model. CLINICAL RELEVANCE: Further clinical studies must be undertaken to identify whether this technique would also be superior when compared with open surgery.

Metallic artifacts from internal scaphoid fracture fixation screws: comparison between C-arm flat-panel, cone-beam, and multidetector computed tomography.

OBJECTIVES: The aim of this study was to compare image quality and extent of artifacts from scaphoid fracture fixation screws using different computed tomography (CT) modalities and radiation dose protocols. MATERIALS AND METHODS: Imaging of 6 cadaveric wrists with artificial scaphoid fractures and different fixation screws was performed in 2 screw positions (45° and 90° orientation in relation to the x/y-axis) using multidetector CT (MDCT) and 2 flat-panel CT modalities, C-arm flat-panel CT (FPCT) and cone-beam CT (CBCT), the latter 2 with low and standard radiation dose protocols. Mean cartilage attenuation and metal artifact-induced absolute Hounsfield unit changes (= artifact extent) were measured. Two independent radiologists evaluated different image quality criteria using a 5-point Likert-scale. Interreader agreements (Cohen κ) were calculated. Mean absolute Hounsfield unit changes and quality ratings were compared using Friedman and Wilcoxon signed-rank tests. RESULTS: Artifact extent was significantly smaller for MDCT and standard-dose FPCT compared with CBCT low- and standard-dose acquisitions (all P < 0.05). No significant differences in artifact extent among different screw types and scanning positions were noted (P > 0.05). Both MDCT and FPCT standard-dose protocols showed equal ratings for screw bone interface, fracture line, and trabecular bone evaluation (P = 0.06, 0.2, and 0.2, respectively) and performed significantly better than FPCT low- and CBCT low- and standard-dose acquisitions (all P < 0.05). Good interreader agreement was found for image quality comparisons (Cohen κ = 0.76-0.78). CONCLUSIONS: Both MDCT and FPCT standard-dose acquisition showed comparatively less metal-induced artifacts and better overall image quality compared with FPCT low-dose and both CBCT acquisitions. Flat-panel CT may provide sufficient image quality to serve as a versatile CT alternative for postoperative imaging of internally fixated wrist fractures.

Standard axillary radiographs of the shoulder may mimic posterior subluxation of the lateral end of the clavicle.

OBJECTIVES: On standard axillary radiographs of normal shoulders, the clavicle may appear subluxated posteriorly. This subluxation might be viewed as an indication for surgical stabilization in acromioclavicular (AC) injury. The purpose of this study was to assess the reliability of identification of anteroposterior displacements of the AC joint on standard axillary radiographs of the human shoulder. METHODS: We performed 170 radiographs of the AC joint in 10 cadaveric shoulders using various projection angles. The distance from the anterior margin of the acromion to the distal clavicle was measured to identify an "optimal" view to image the true anteroposterior alignment of normal AC joints. RESULTS: On the standard axillary view of intact shoulders, we found an average posterior translation of 1.7 mm (range, -3 to 7; SD, 2.8) and of 0.9 mm (range, -5 to 5; SD, 2.8) in an "optimal view," tilted 15 degees dorsal and 15 degees lateral. CONCLUSIONS: The standard axillary radiograph has a very high sensitivity but poor accuracy in identifying a posterior clavicular translation in the AC joint. We could not identify a reliable modification of the axillary radiographic projection to improve the accuracy. Therefore, an apparent posterior subluxation of the clavicle identified on an axillary radiograph is more likely a false positive finding than an identification of a true pathology.