Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Stress-induced transcriptional memory accelerates promoter-proximal pause release and decelerates termination over mitotic divisions.

Vihervaara, Anniina; Mahat, Dig Bijay; Himanen, Samu V; Blom, Malin A H; Lis, John T; Sistonen, Lea.

Mol Cell ; 81(8): 1715-1731.e6, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33784494

2.

Enhancer transcription: what, where, when, and why?

Tippens, Nathaniel D; Vihervaara, Anniina; Lis, John T.

Genes Dev ; 32(1): 1-3, 2018 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-29440223

3.

Nascent RNA analyses: tracking transcription and its regulation.

Wissink, Erin M; Vihervaara, Anniina; Tippens, Nathaniel D; Lis, John T.

Nat Rev Genet ; 20(12): 705-723, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31399713

4.

Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.

Wang, Zhijia; Himanen, Samu V; Haikala, Heidi M; Friedel, Caroline C; Vihervaara, Anniina; Barboric, Matjaz.

Nucleic Acids Res ; 51(20): 10970-10991, 2023 11 10.

Artigo em Inglês | MEDLINE | ID: mdl-37811895

5.

Molecular mechanisms driving transcriptional stress responses.

Vihervaara, Anniina; Duarte, Fabiana M; Lis, John T.

Nat Rev Genet ; 19(6): 385-397, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29556092

6.

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock.

Himanen, Samu V; Puustinen, Mikael C; Da Silva, Alejandro J; Vihervaara, Anniina; Sistonen, Lea.

Nucleic Acids Res ; 50(11): 6102-6115, 2022 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-35687139

7.

Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation.

Burchfiel, Eileen T; Vihervaara, Anniina; Guertin, Michael J; Gomez-Pastor, Rocio; Thiele, Dennis J.

J Biol Chem ; 296: 100097, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33208463

8.

Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock.

Ray, Judhajeet; Munn, Paul R; Vihervaara, Anniina; Lewis, James J; Ozer, Abdullah; Danko, Charles G; Lis, John T.

Proc Natl Acad Sci U S A ; 116(39): 19431-19439, 2019 09 24.

Artigo em Inglês | MEDLINE | ID: mdl-31506350

9.

Uniting diversity to create a more inclusive academic environment.

Delemotte, Lucie; Garcia, Sarahi L; Rodríguez-Gijón, Alejandro; Sezgin, Erdinc; Vihervaara, Anniina.

J Cell Sci ; 135(7)2022 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-35411385

10.

HSF1 at a glance.

Vihervaara, Anniina; Sistonen, Lea.

J Cell Sci ; 127(Pt 2): 261-6, 2014 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-24421309

11.

Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.

Vihervaara, Anniina; Sergelius, Christian; Vasara, Jenni; Blom, Malin A H; Elsing, Alexandra N; Roos-Mattjus, Pia; Sistonen, Lea.

Proc Natl Acad Sci U S A ; 110(36): E3388-97, 2013 Sep 03.

Artigo em Inglês | MEDLINE | ID: mdl-23959860

12.

Stress biology: Complexity and multifariousness in health and disease.

Mayer, Matthias P; Blair, Laura; Blatch, Gregory L; Borges, Thiago J; Chadli, Ahmed; Chiosis, Gabriela; de Thonel, Aurélie; Dinkova-Kostova, Albena; Ecroyd, Heath; Edkins, Adrienne L; Eguchi, Takanori; Fleshner, Monika; Foley, Kevin P; Fragkostefanakis, Sotirios; Gestwicki, Jason; Goloubinoff, Pierre; Heritz, Jennifer A; Heske, Christine M; Hibshman, Jonathan D; Joutsen, Jenny; Li, Wei; Lynes, Michael; Mendillo, Marc L; Mivechi, Nahid; Mokoena, Fortunate; Okusha, Yuka; Prahlad, Veena; Repasky, Elizabeth; Sannino, Sara; Scalia, Federica; Shalgi, Reut; Sistonen, Lea; Sontag, Emily; van Oosten-Hawle, Patricija; Vihervaara, Anniina; Wickramaratne, Anushka; Wang, Shawn Xiang Yang; Zininga, Tawanda.

Cell Stress Chaperones ; 29(1): 143-157, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38311120

13.

PRO-IP-seq Tracks Molecular Modifications of Engaged Pol II Complexes at Nucleotide Resolution.

Vihervaara, Anniina; Versluis, Philip; Lis, John T.

bioRxiv ; 2023 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-36778434

14.

PRO-IP-seq tracks molecular modifications of engaged Pol II complexes at nucleotide resolution.

Vihervaara, Anniina; Versluis, Philip; Himanen, Samu V; Lis, John T.

Nat Commun ; 14(1): 7039, 2023 11 03.

Artigo em Inglês | MEDLINE | ID: mdl-37923726

15.

Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data.

Rabenius, Adelina; Chandrakumaran, Sajitha; Sistonen, Lea; Vihervaara, Anniina.

STAR Protoc ; 3(1): 101036, 2022 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-35036951

16.

CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

de Thonel, Aurélie; Ahlskog, Johanna K; Daupin, Kevin; Dubreuil, Véronique; Berthelet, Jérémy; Chaput, Carole; Pires, Geoffrey; Leonetti, Camille; Abane, Ryma; Barris, Lluís Cordón; Leray, Isabelle; Aalto, Anna L; Naceri, Sarah; Cordonnier, Marine; Benasolo, Carène; Sanial, Matthieu; Duchateau, Agathe; Vihervaara, Anniina; Puustinen, Mikael C; Miozzo, Federico; Fergelot, Patricia; Lebigot, Élise; Verloes, Alain; Gressens, Pierre; Lacombe, Didier; Gobbo, Jessica; Garrido, Carmen; Westerheide, Sandy D; David, Laurent; Petitjean, Michel; Taboureau, Olivier; Rodrigues-Lima, Fernando; Passemard, Sandrine; Sabéran-Djoneidi, Délara; Nguyen, Laurent; Lancaster, Madeline; Sistonen, Lea; Mezger, Valérie.

Nat Commun ; 13(1): 7002, 2022 11 16.

Artigo em Inglês | MEDLINE | ID: mdl-36385105

17.

Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.

Akerfelt, Malin; Vihervaara, Anniina; Laiho, Asta; Conter, Annie; Christians, Elisabeth S; Sistonen, Lea; Henriksson, Eva.

J Biol Chem ; 285(45): 34469-76, 2010 Nov 05.

Artigo em Inglês | MEDLINE | ID: mdl-20802198

18.

Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2.

Akerfelt, Malin; Henriksson, Eva; Laiho, Asta; Vihervaara, Anniina; Rautoma, Karoliina; Kotaja, Noora; Sistonen, Lea.

Proc Natl Acad Sci U S A ; 105(32): 11224-9, 2008 Aug 12.

Artigo em Inglês | MEDLINE | ID: mdl-18682557

19.

Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

de Thonel, Aurélie; Ahlskog, Johanna K; Daupin, Kevin; Dubreuil, Véronique; Berthelet, Jérémy; Chaput, Carole; Pires, Geoffrey; Leonetti, Camille; Abane, Ryma; Barris, Lluís Cordón; Leray, Isabelle; Aalto, Anna L; Naceri, Sarah; Cordonnier, Marine; Benasolo, Carène; Sanial, Matthieu; Duchateau, Agathe; Vihervaara, Anniina; Puustinen, Mikael C; Miozzo, Federico; Fergelot, Patricia; Lebigot, Élise; Verloes, Alain; Gressens, Pierre; Lacombe, Didier; Gobbo, Jessica; Garrido, Carmen; Westerheide, Sandy D; David, Laurent; Petitjean, Michel; Taboureau, Olivier; Rodrigues-Lima, Fernando; Passemard, Sandrine; Sabéran-Djoneidi, Délara; Nguyen, Laurent; Lancaster, Madeline; Sistonen, Lea; Mezger, Valérie.

Nat Commun ; 14(1): 6067, 2023 Sep 28.

Artigo em Inglês | MEDLINE | ID: mdl-37770591

20.

Transcriptional response to stress is pre-wired by promoter and enhancer architecture.

Vihervaara, Anniina; Mahat, Dig Bijay; Guertin, Michael J; Chu, Tinyi; Danko, Charles G; Lis, John T; Sistonen, Lea.

Nat Commun ; 8(1): 255, 2017 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-28811569

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