Detalhe da pesquisa
1.
Ciraparantag, an anticoagulant reversal drug: mechanism of action, pharmacokinetics, and reversal of anticoagulants.
Blood
; 137(1): 115-125, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205809
2.
Ciraparantag reverses the anticoagulant activity of apixaban and rivaroxaban in healthy elderly subjects.
Eur Heart J
; 43(10): 985-992, 2022 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34534272
3.
Maribavir for Preemptive Treatment of Cytomegalovirus Reactivation.
N Engl J Med
; 381(12): 1136-1147, 2019 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31532960
4.
Omadacycline for Acute Bacterial Skin and Skin-Structure Infections.
N Engl J Med
; 380(6): 528-538, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726689
5.
An Open-Label Study of the Impact of Hepatic Impairment on the Pharmacokinetics and Safety of Single Oral and Intravenous Doses of Omadacycline.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32839218
6.
Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid-organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study.
Clin Infect Dis
; 68(8): 1255-1264, 2019 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30329038
7.
Safety and Pharmacokinetics of the Aminomethylcycline Antibiotic Omadacycline Administered to Healthy Subjects in Oral Multiple-Dose Regimens.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180524
8.
Pharmacokinetics and Safety of Omadacycline in Subjects with Impaired Renal Function.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158281
9.
Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline following a Single Intravenous or Oral Dose of 14C-Omadacycline in Rats.
Antimicrob Agents Chemother
; 61(1)2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27821446
10.
Comparison of Omadacycline and Tigecycline Pharmacokinetics in the Plasma, Epithelial Lining Fluid, and Alveolar Cells of Healthy Adult Subjects.
Antimicrob Agents Chemother
; 61(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28696233
11.
Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline.
Xenobiotica
; 47(8): 682-696, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499331
12.
In Vitro and In Vivo Assessments of Cardiovascular Effects with Omadacycline.
Antimicrob Agents Chemother
; 60(9): 5247-53, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27324778
13.
Randomized, Open-Label Study of the Pharmacokinetics and Safety of Oral and Intravenous Administration of Omadacycline to Healthy Subjects.
Antimicrob Agents Chemother
; 60(12): 7431-7435, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27736760
14.
Discovery, pharmacology, and clinical profile of omadacycline, a novel aminomethylcycline antibiotic.
Bioorg Med Chem
; 24(24): 6409-6419, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27469981
15.
Correction for Kovacs et al., "An Open-Label Study of the Impact of Hepatic Impairment on the Pharmacokinetics and Safety of Single Oral and Intravenous Doses of Omadacycline".
Antimicrob Agents Chemother
; 65(1)2020 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33328319
16.
Administration of spores of nontoxigenic Clostridium difficile strain M3 for prevention of recurrent C. difficile infection: a randomized clinical trial.
JAMA
; 313(17): 1719-27, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25942722
17.
Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects.
Antimicrob Agents Chemother
; 56(10): 5224-9, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22850511
18.
Virologic characterization of multidrug-resistant cytomegalovirus infection in 2 transplant recipients treated with maribavir.
J Infect Dis
; 202(1): 104-8, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20504236
19.
HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus.
Hepatology
; 49(3): 745-52, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19072827
20.
Maribavir prophylaxis for prevention of cytomegalovirus infection in allogeneic stem cell transplant recipients: a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study.
Blood
; 111(11): 5403-10, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18285548