Detalhe da pesquisa
1.
A Diverse Array of Large Capsules Transform in Response to Stimuli.
J Am Chem Soc
; 145(20): 11356-11363, 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191451
2.
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
J Med Chem
; 64(7): 4071-4088, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761253
3.
4-Acetamido-N-(λ-triphenyl-phospho-ranyl-idene)benzene-sulfonamide.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 5): o1098-9, 2010 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21579151
4.
Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator.
J Med Chem
; 51(2): 183-6, 2008 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18163548
5.
Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
ChemMedChem
; 9(4): 823-32, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24616449
6.
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design.
J Med Chem
; 53(16): 5956-69, 2010 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20662534
7.
Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity.
J Med Chem
; 52(2): 379-88, 2009 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19143567
8.
High-throughput protein crystallography and drug discovery.
Chem Soc Rev
; 33(8): 558-65, 2004 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15480479
9.
Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase.
EMBO J
; 22(23): 6193-204, 2003 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14633979