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1.
Gastrointest Endosc ; 78(5): 726-33, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23891416

RESUMO

BACKGROUND: Long-term results of extracorporeal shockwave lithotripsy (ESWL) for large pancreatic duct (PD) stones in patients with idiopathic calcific pancreatitis (CP) are scanty. OBJECTIVE: To evaluate intermediate and long-term results of ESWL in a large cohort of patients with idiopathic CP. DESIGN: Cross-sectional study; retrospective chart review. SETTING: A high-volume, tertiary-care center for endoscopy and GI diseases. PATIENTS: A total of 636 patients with idiopathic CP who underwent ESWL and ERCP were followed-up. Patients were divided into intermediate (24-60 months) and long-term (>60 months) follow-up groups. INTERVENTION: ESWL and ERCP. MAIN OUTCOME MEASUREMENTS: Improvement in pain, analgesic use, hospitalization for pain, recurrence of calculi, need for additional intervention, and quality of life. RESULTS: A total of 636 of 1006 patients who underwent ESWL between 2004 and 2009 were followed for a maximum of 96 months. There were 364 patients in the intermediate follow-up group and 272 in the long-term follow-up group. After ESWL and ERCP, absence of pain was seen in 250 patients (68.7%), mild-to-moderate pain in 94 patients (25.4%), and severe pain in 20 patients (5.5%) of the intermediate group. In the long-term group, 164 patients (60.3%) had no pain, 97 patients (35.7%) had mild or moderate episodes of pain, whereas 11 patients (4.04%) had episodic severe pain. Recurrence of calculi was seen in 51 patients (14.01%) in the intermediate follow-up group and in 62 patients (22.8%) in the long-term group. Quality of life improved in a significant number of patients in both groups. LIMITATIONS: Retrospective study, single center, recall bias, and subjective pain and quality-of-life measurement scale. CONCLUSION: ESWL for large PD calculi offers good results in patients of idiopathic CP on intermediate and long-term follow-up.


Assuntos
Dor Abdominal/terapia , Cálculos/terapia , Litíase/terapia , Litotripsia/métodos , Pancreatite Crônica/terapia , Dor Abdominal/etiologia , Adulto , Analgésicos/uso terapêutico , Cálculos/complicações , Colangiopancreatografia Retrógrada Endoscópica , Estudos de Coortes , Estudos Transversais , Feminino , Hospitalização , Humanos , Litíase/complicações , Estudos Longitudinais , Masculino , Medição da Dor , Ductos Pancreáticos , Pancreatite Crônica/complicações , Qualidade de Vida , Recidiva , Estudos Retrospectivos , Esfinterotomia Endoscópica , Resultado do Tratamento
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