RESUMO
The presence of antibodies against some important respiratory viruses in the middle ear and nasopharyngeal secretions of 52 children with secretory otitis media (SOM) was investigated in order to find out about the role of these viruses in the development of SOM. The method employed was a sensitive radioimmunoassay test. Antibodies to adeno, syncytial, and parainfluenza 3 viruses were detected in about 50%, 50% and 20% of the patients, respectively. In eight patients the middle ear secretion/nasopharyngeal secretion titer ratio of antibodies to one virus was selectively increased in comparison with the other viruses tested, indicating an active local production of specific antibodies in the middle ear. Further studies are required to determine the cause of such an active antibody synthesis and its possible role in the etiopathogenesis of SOM.
Assuntos
Anticorpos Antivirais/análise , Exsudatos e Transudatos/imunologia , Imunoglobulina A/análise , Nasofaringe/metabolismo , Otite Média com Derrame/imunologia , Otite Média/imunologia , Adenoviridae/imunologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Vírus da Influenza A/imunologia , Masculino , Radioimunoensaio , Vírus Sinciciais Respiratórios/imunologia , Respirovirus/imunologiaRESUMO
The threshold of nystagmus during angular acceleration and deceleration was investigated in two series of healthy persons with an average age of 20 and 42 years and in series of otosclerotic patients with an average age of 42 years. It was shown that age as such does not influence the thresholds, but a lesion in the inner ear, such as otosclerosis, causes higher thresholds even in younger subjects.
Assuntos
Envelhecimento , Movimentos Oculares , Otosclerose/fisiopatologia , Vestíbulo do Labirinto/fisiopatologia , Aceleração , Adolescente , Adulto , Desaceleração , Eletronistagmografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , RotaçãoRESUMO
The Rinne and the Weber tests were carried out using a 256-Hz tuning fork on 687 6- to 15-year-old school children, the majority of whom were normally hearing subjects. The Rinne test was positive in 97% of ears with normal hearing or sensorineural hearing loss and negative in 72% of ears with conductive hearing loss. The Rinne test changed from positive to negative at 13 dB when performed using the normal loudness comparison method. In midline Weber results, the mean value of the air conduction difference at 0.25 kHz between the right and left ear was 1.4 dB. The lateralization in the Weber test occurred at a difference of 2.5 dB between the right and left ear. The Weber test was in midline in 96-98% of ears with bilateral normal hearing or sensorineural hearing loss. It lateralized to the poorer ear in 63% of ears with unilateral conductive hearing loss. The values of the Rinne and Weber tests were not good in the diagnosis of mild conductive hearing loss when the air-bone gap was 5-35 dB.