Detalhe da pesquisa
1.
Copper Ionophores as Novel Antiobesity Therapeutics.
Molecules
; 25(21)2020 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33120881
2.
Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells.
Pharm Res
; 35(4): 83, 2018 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29508078
3.
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse.
Neurobiol Dis
; 81: 168-75, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25796563
4.
Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.
Neurobiol Dis
; 71: 34-42, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25014023
5.
Ceruloplasmin gene-deficient mice with experimental autoimmune encephalomyelitis show attenuated early disease evolution.
J Neurosci Res
; 92(6): 732-42, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24615902
6.
Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity.
J Biol Chem
; 286(11): 9776-86, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21239495
7.
Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.
J Biol Chem
; 286(20): 18320-30, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454633
8.
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Proc Natl Acad Sci U S A
; 106(2): 381-6, 2009 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19122148
9.
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
Biochemistry
; 50(13): 2611-22, 2011 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21348480
10.
The Alzheimer's therapeutic PBT2 promotes amyloid-ß degradation and GSK3 phosphorylation via a metal chaperone activity.
J Neurochem
; 119(1): 220-30, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21797865
11.
Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes.
Inorg Chem
; 50(19): 9594-605, 2011 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21882803
12.
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Proc Natl Acad Sci U S A
; 105(19): 6813-8, 2008 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18463291
13.
Deferiprone Treatment in Aged Transgenic Tau Mice Improves Y-Maze Performance and Alters Tau Pathology.
Neurotherapeutics
; 18(2): 1081-1094, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33410108
14.
Manganese chelation therapy extends survival in a mouse model of M1000 prion disease.
J Neurochem
; 114(2): 440-51, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20456001
15.
Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain.
Biometals
; 23(6): 1085-95, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20556483
16.
Regional iron distribution and soluble ferroprotein profiles in the healthy human brain.
Prog Neurobiol
; 186: 101744, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31870805
17.
CuII (atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease.
Br J Pharmacol
; 177(3): 656-667, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31655003
18.
Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology.
Metallomics
; 12(1): 114-132, 2020 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31764918
19.
Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice.
Cell Mol Neurobiol
; 29(5): 757-67, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19381799
20.
Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms.
Biochem J
; 412(1): 141-52, 2008 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18248325