Detalhe da pesquisa
1.
Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain.
Neurochem Res
; 45(6): 1256-1267, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749072
2.
Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers.
J Transl Med
; 13: 170, 2015 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26021605
3.
Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism.
J Pharmacol Exp Ther
; 346(3): 406-13, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23776202
4.
The orally active glutamate carboxypeptidase II inhibitor E2072 exhibits sustained nerve exposure and attenuates peripheral neuropathy.
J Pharmacol Exp Ther
; 343(3): 746-54, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988061
5.
We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine.
Mol Cancer Ther
; 17(9): 1824-1832, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30181331
6.
Ghrelin agonist HM01 attenuates chemotherapy-induced neurotoxicity in rodent models.
Eur J Pharmacol
; 840: 89-103, 2018 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30268665
7.
Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery.
Cancer Res
; 78(3): 817-829, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29191802
8.
Sustained Accumulation of Microtubule-Binding Chemotherapy Drugs in the Peripheral Nervous System: Correlations with Time Course and Neurotoxic Severity.
Cancer Res
; 76(11): 3332-9, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27197173
9.
FOLH1/GCPII is elevated in IBD patients, and its inhibition ameliorates murine IBD abnormalities.
JCI Insight
; 1(12)2016 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27536732
10.
Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective N-methyl-D-aspartate receptor antagonist.
Pharmacol Res Perspect
; 3(6): e00198, 2015 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27022470
11.
Sedation with GPI 15715, a water-soluble prodrug of propofol, using target-controlled infusion in volunteers.
Anesth Analg
; 100(3): 701-706, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15728055
12.
Pharmacokinetics and clinical pharmacodynamics of the new propofol prodrug GPI 15715 in volunteers.
Anesthesiology
; 99(2): 303-13, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12883403
13.
Comparative pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 and propofol emulsion.
Anesthesiology
; 101(3): 626-39, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15329587