Detalhe da pesquisa
1.
Symmetric arrangement of mitochondria:plasma membrane contacts between adjacent photoreceptor cells regulated by Opa1.
Proc Natl Acad Sci U S A
; 117(27): 15684-15693, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571921
2.
Research priorities for mitochondrial disorders: Current landscape and patient and professional views.
J Inherit Metab Dis
; 45(4): 796-803, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35543492
3.
Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy.
Int J Mol Sci
; 22(11)2021 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34072974
4.
Red Light Irradiation In Vivo Upregulates DJ-1 in the Retinal Ganglion Cell Layer and Protects against Axotomy-Related Dendritic Pruning.
Int J Mol Sci
; 22(16)2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445085
5.
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Ann Neurol
; 86(3): 368-383, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31298765
6.
Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy.
J Neuroophthalmol
; 40(4): 558-565, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991388
7.
Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity.
Hum Mol Genet
; 25(12): 2404-2416, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27106103
8.
Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy-Response to Dr. Finsterer's Letter.
J Neuroophthalmol
; 43(3): e96, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387631
9.
International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy.
J Neuroophthalmol
; 37(4): 371-381, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28991104
10.
A neurodegenerative perspective on mitochondrial optic neuropathies.
Acta Neuropathol
; 132(6): 789-806, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27696015
11.
Clinical and molecular genetic findings in autosomal dominant OPA3-related optic neuropathy.
Neurogenetics
; 16(1): 69-75, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25159689
12.
Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome.
Hum Mol Genet
; 21(22): 4836-44, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22869679
13.
Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial.
Cell Rep Med
; 5(3): 101437, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38428428
14.
Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity.
Brain
; 135(Pt 2): 493-505, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22300878
15.
Specific deficits in visual electrophysiology in a mouse model of dominant optic atrophy.
Exp Eye Res
; 93(5): 771-7, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21803037
16.
Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy.
Brain
; 133(10): 2942-51, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20817698
17.
A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1.
Front Neurol
; 12: 641259, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33927681
18.
New avenues for therapy in mitochondrial optic neuropathies.
Ther Adv Rare Dis
; 2: 26330040211029037, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-37181108
19.
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction.
Redox Biol
; 43: 101988, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932867
20.
Opa1 Deficiency Leads to Diminished Mitochondrial Bioenergetics With Compensatory Increased Mitochondrial Motility.
Invest Ophthalmol Vis Sci
; 61(6): 42, 2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32561926