Detalhe da pesquisa
1.
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Nature
; 586(7831): 769-775, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33057200
2.
Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.
Proc Natl Acad Sci U S A
; 117(42): 26340-26346, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020282
3.
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
Haematologica
; 107(5): 1034-1044, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261293
4.
Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia.
Haematologica
; 105(3): 721-729, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413100
5.
Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
Proc Natl Acad Sci U S A
; 114(36): 9629-9634, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827320
6.
MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies.
Proc Natl Acad Sci U S A
; 112(49): E6744-51, 2015 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582795
7.
A phase 1 clinical trial of oral eltanexor in patients with relapsed or refractory multiple myeloma.
Am J Hematol
; 97(2): E54-E58, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34817872
8.
Traditional Approaches to Molecular Genetic Analysis.
Adv Exp Med Biol
; 943: 99-118, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27910066
9.
NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.
Proc Natl Acad Sci U S A
; 111(11): 4179-84, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24586049
10.
MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair.
Hum Mutat
; 37(10): 1004-12, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346418
11.
Estrogen receptor-alpha as a predictive biomarker in endometrioid endometrial cancer.
Gynecol Oncol
; 141(2): 312-317, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26957478
12.
Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies.
Blood
; 122(11): 1923-34, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23926298
13.
Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.
Blood
; 122(17): 3034-44, 2013 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23970380
14.
Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG).
Leukemia
; 38(1): 45-57, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017103
15.
Impacting T-cell fitness in multiple myeloma: potential roles for selinexor and XPO1 inhibitors.
Front Immunol
; 14: 1275329, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37954586
16.
NAD+ Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females.
Endocrinology
; 164(6)2023 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37170651
17.
Dual targeting of protein translation and nuclear protein export results in enhanced antimyeloma effects.
Blood Adv
; 7(12): 2926-2937, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36827679
18.
Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma.
Exp Hematol Oncol
; 12(1): 78, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37715291
19.
XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression.
Leukemia
; 37(10): 2036-2049, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37528310
20.
An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia.
Nat Cancer
; 4(1): 27-42, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36581735