Detalhe da pesquisa
1.
CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia.
Int J Mol Sci
; 24(17)2023 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686014
2.
The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia.
Haematologica
; 106(2): 630-634, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32381579
3.
Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo.
Haematologica
; 103(4): e147-e150, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29419436
4.
High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling.
Biomedicines
; 10(3)2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327440
5.
Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia.
Biomedicines
; 9(7)2021 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34201500
6.
High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia.
Transl Oncol
; 14(5): 101048, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667892
7.
Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia.
Leukemia
; 34(11): 2898-2902, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32488115
8.
FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.
Leukemia
; 33(9): 2310-2314, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30953031