Detalhe da pesquisa
1.
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
Nature
; 609(7927): 590-596, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002575
2.
Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.
FASEB J
; 35(9): e21813, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390512
3.
Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.
EMBO Rep
; 21(10): e50241, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929860
4.
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
EMBO J
; 36(13): 1837-1853, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559417
5.
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Acta Neuropathol
; 140(2): 121-142, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32562018
6.
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Methods
; 121-122: 55-67, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263886
7.
Control of gene editing by manipulation of DNA repair mechanisms.
Mamm Genome
; 28(7-8): 262-274, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28374058
8.
Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.
Proc Natl Acad Sci U S A
; 110(10): 3782-7, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426636
9.
Generation of targeted mouse mutants by embryo microinjection of TALENs.
Methods
; 69(1): 94-101, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24418396
10.
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
Sleep
; 47(5)2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38314840
11.
Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System.
Methods Mol Biol
; 2631: 207-230, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36995669
12.
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
Nat Protoc
; 16(3): 1714-1739, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597771
13.
Editing and investigating genomes with TALE and CRISPR/Cas systems: genome engineering across species using TALENs.
Methods
; 69(1): 1, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25194988
14.
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
Mol Neurodegener
; 15(1): 52, 2020 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917267
15.
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
Cell Rep
; 30(10): 3506-3519.e6, 2020 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160553
16.
Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference.
Mol Biotechnol
; 41(3): 263-9, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19052925
17.
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
Mol Neurodegener
; 13(1): 49, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185230
18.
Genome Editing in Mice Using TALE Nucleases.
Methods Mol Biol
; 1338: 229-43, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26443225
19.
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Nat Biotechnol
; 33(5): 543-8, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25803306
20.
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
FEBS Open Bio
; 5: 26-35, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25685662