Detalhe da pesquisa
1.
Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.
Cell
; 164(4): 644-55, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26871630
2.
Strand-resolved mutagenicity of DNA damage and repair.
Nature
; 630(8017): 744-751, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38867042
3.
Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture.
Proc Natl Acad Sci U S A
; 117(19): 10541-10546, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32332169
4.
Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay.
Proc Natl Acad Sci U S A
; 115(8): 1919-1924, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29432181
5.
DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.
Proc Natl Acad Sci U S A
; 115(4): 762-767, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311308
6.
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination.
Proc Natl Acad Sci U S A
; 115(34): 8615-8620, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30072430
7.
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease.
Mol Cell
; 48(5): 747-59, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23123197
8.
Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.
Proc Natl Acad Sci U S A
; 113(8): 2258-63, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26873106
9.
A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress.
Nucleic Acids Res
; 41(3): 1533-43, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23241391
10.
Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress.
Nucleic Acids Res
; 40(1): 323-32, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908404
11.
Linear Interaction Between Replication and Transcription Shapes DNA Break Dynamics at Recurrent DNA Break Clusters.
bioRxiv
; 2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37662334
12.
Linear interaction between replication and transcription shapes DNA break dynamics at recurrent DNA break Clusters.
Nat Commun
; 15(1): 3594, 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38678011
13.
Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.
Free Radic Biol Med
; 165: 368-384, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33460768
14.
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Neuro Oncol
; 23(12): 2028-2041, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049392
15.
Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability.
Cell Stem Cell
; 26(2): 221-233.e6, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32004479
16.
STAT2 hypomorphic mutant mice display impaired dendritic cell development and antiviral response.
J Biomed Sci
; 16: 22, 2009 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19272190
17.
Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation.
Mol Neurobiol
; 56(6): 3972-3983, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30238389
18.
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors.
Nat Commun
; 9(1): 4760, 2018 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420702
19.
TGF-ß1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB.
EMBO Mol Med
; 9(12): 1660-1680, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993429
20.
NPGPx (GPx7): a novel oxidative stress sensor/transmitter with multiple roles in redox homeostasis.
Am J Transl Res
; 8(4): 1626-40, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27186289