Detalhe da pesquisa
1.
Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
Cell
; 157(3): 636-50, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24766809
2.
The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol Cell
; 81(12): 2520-2532.e16, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33930333
3.
CLP1 links tRNA metabolism to progressive motor-neuron loss.
Nature
; 495(7442): 474-80, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23474986
4.
Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.
Biochem Soc Trans
; 41(4): 831-7, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863140
5.
The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
Nature
; 447(7141): 222-6, 2007 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17495927
6.
Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes.
Cell Rep
; 39(2): 110636, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417719
7.
Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Nat Commun
; 12(1): 5610, 2021 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34584079
8.
Molecular architecture of the human tRNA ligase complex.
Elife
; 102021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34854379
9.
The TLR-independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature.
Eur J Immunol
; 39(7): 1929-36, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19551900
10.
ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.
Science
; 369(6503): 524-530, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32732418
11.
Chromosome segregation: playing polo in prophase.
Dev Cell
; 2(4): 381-2, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11970886
12.
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress.
J Clin Invest
; 129(10): 4194-4206, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31449058
13.
A model for ATP hydrolysis-dependent binding of cohesin to DNA.
Curr Biol
; 13(22): 1930-40, 2003 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-14614818
14.
CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.
Wiley Interdiscip Rev RNA
; 6(1): 47-63, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25142875
15.
HSPC117 is the essential subunit of a human tRNA splicing ligase complex.
Science
; 331(6018): 760-4, 2011 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21311021
16.
hClp1: a novel kinase revitalizes RNA metabolism.
Cell Cycle
; 6(17): 2133-7, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17786051
17.
In vivo analysis of cohesin architecture using FRET in the budding yeast Saccharomyces cerevisiae.
EMBO J
; 26(16): 3783-93, 2007 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17660750