Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros

Bases de dados
País/Região como assunto
Ano de publicação
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
Viruses ; 16(2)2024 02 16.
Artigo em Inglês | MEDLINE | ID: mdl-38400077

RESUMO

The hepatitis E virus is a major etiological agent of chronic hepatitis in immunosuppressed individuals. Seroprevalence in the liver transplantation setting varies according to the seroprevalence of the general population in different countries. This was a prospective cohort study of liver transplant recipients in southeastern Brazil. Recipients were systematically followed for one year, with the objective of determining the prevalence, incidence, and natural history of HEV infection in this population. We included 107 liver transplant recipients and 83 deceased donors. Positivity for anti-HEV IgG was detected in 10.2% of the recipients and in 9.7% of the donors. None of the patients tested positive for HEV RNA at baseline or during follow-up. There were no episodes of reactivation or seroconversion, even in cases of serological donor-recipient mismatch or in recipients with acute hepatitis. Acute and chronic HEV infections seem to be rare events in the region studied. That could be attributable to social, economic, and environmental factors. Our data indicate that, among liver transplant recipients, hepatitis E should be investigated only when there are elevated levels of transaminases with no defined cause, as part of the differential diagnosis of seronegative hepatitis after transplantation.


Assuntos
Vírus da Hepatite E , Hepatite E , Transplante de Fígado , Humanos , Vírus da Hepatite E/genética , Transplante de Fígado/efeitos adversos , Estudos Prospectivos , Brasil/epidemiologia , Estudos Soroepidemiológicos , Reinfecção , RNA Viral/genética , Estudos de Coortes , Anticorpos Anti-Hepatite , Infecção Persistente
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA