RESUMO
OBJECTIVES: The aim of this study was to comprehensively assess the literature in terms of the effect of peri-implant mucosal thickness on esthetic outcomes and the efficacy of soft tissue augmentation procedures to increase the mucosal thickness with autogenous grafts or soft tissue substitutes. MATERIAL AND METHODS: Two systematic reviews (SR) were performed prior to the consensus meeting to assess the following questions. Review 1, focused question: In systemically healthy patients with an implant-supported fixed prosthesis, what is the influence of thin as compared to thick peri-implant mucosa on esthetic outcomes? Review 2, focused question 1: In systemically healthy humans with at least one dental implant (immediate or staged implant), what is the efficacy of connective tissue graft (CTG), as compared to absence of a soft tissue grafting procedure, in terms of gain in peri-implant soft tissue thickness (STT) reported by randomized controlled clinical trials (RCTs) or controlled clinical trials (CCTs)? Review 2, focused question 2: In systemically healthy humans with at least one dental implant (immediate or staged implant), what is the efficacy of CTG, as compared to soft tissue substitutes, in terms of gain in peri-implant STT reported by RCTs or CCTs? The outcomes of the two SRs, the consensus statements, the clinical implications, and the research recommendations were discussed and subsequently approved at the consensus meeting during the group and plenary sessions. CONCLUSIONS: There was a tendency of superior esthetic outcomes in the presence of a thick mucosa. The connective tissue graft remains the standard of care in terms of increasing mucosa thickness.
Assuntos
Implantes Dentários , Autoenxertos , Consenso , Estética Dentária , Humanos , MucosaRESUMO
It was the aim of this study to histometrically evaluate guided tissue regeneration (bioresorbable membrane plus bone mineral) (GTR) with or without platelet-derived growth factor (PDGF) in two different types of class III furcation defects (small keyhole defects and horizonal defects) in monkeys. In six cynomolgus monkeys, two types of class III furcation defects were created and allowed to chronify for 5 months in mandibular first and second molars. After a hygiene program the molars were assigned to GTR group (collagen membrane plus bovine bone mineral), PDGF group (collagen membrane plus bovine bone mineral plus PDGF), or negative control group (flap reposition only). Histologic sections were made after 7 months of healing and descriptive statistics were provided from the histometric parameters. Postoperative healing was uneventful despite marginal membrane exposures in the GTR and PDGF group. Bone regeneration of 23-35% of the original defect area was found in the two treatment groups. In none of the evaluated key parameters (formation of bone, root cementum, connective tissue, or epithelium) differences were detected between GTR and PDGF groups. However, the negative control teeth exhibited better bone regeneration than the treatment groups. The type of class III defect did not influence the regenerative outcome. Within the limits of this study PDGF was not able to enhance the histologic regeneration of class III furcation areas in monkeys compared to bone mineral enhanced GTR treatment regardless of the defect configuration. Membrane exposure during early healing might have influenced these outcomes.
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PURPOSE: It is unknown whether different microgap configurations can cause different peri-implant bone reactions. Therefore, this study sought to compare the peri-implant bone morphologies of two implant systems with different implant-abutment connections. MATERIALS AND METHODS: Three months after mandibular tooth extractions in six mongrel dogs, two oxidized screw implants with an external-hex connection were inserted (hexed group) on one side, whereas on the contralateral side two grit-blasted screw implants with an internal Morse-taper connection (Morse group) were placed. On each side, one implant was inserted level with the bone (equicrestal) and the second implant was inserted 1.5 mm below the bony crest (subcrestal). Healing abutments were inserted immediately after implant placement. Three months later, the peri-implant bone levels, the first bone-to-implant contact points, and the width and steepness of the peri-implant bone defects were evaluated histometrically. RESULTS: All 24 implants osseointegrated clinically and histologically. No statistically significant differences between the hexed group and Morse group were detected for either the vertical position for peri-implant bone levels (Morse equicrestal -0.16 mm, hexed equicrestal -0.22 mm, Morse subcrestal 1.50 mm, hexed subcrestal 0.94 mm) or for the first bone-to-implant contact points (Morse equicrestal -2.08 mm, hexed equicrestal -0.98 mm, Morse subcrestal -1.26 mm, hexed subcrestal -0.76 mm). For the parameters width (Morse equicrestal -0.15 mm, hexed equicrestal -0.59 mm, Morse subcrestal 0.28 mm, hexed subcrestal -0.70 mm) and steepness (Morse equicrestal 25.27 degree, hexed equicrestal 57.21 degree, Morse subcrestal 15.35 degree, hexed subcrestal 37.97 degree) of the peri-implant defect, highly significant differences were noted between the Morse group and the hexed group. CONCLUSION: Within the limits of this experiment, it can be concluded that different microgap configurations influence the size and shape of the peri-implant bone defect in nonsubmerged implants placed both at the crest and subcrestally.
Assuntos
Perda do Osso Alveolar/etiologia , Dente Suporte , Implantação Dentária Endóssea/métodos , Implantes Dentários , Planejamento de Prótese Dentária/efeitos adversos , Perda do Osso Alveolar/patologia , Animais , Implantação Dentária Endóssea/efeitos adversos , Cães , Implantes Experimentais , OsseointegraçãoRESUMO
PURPOSE: This dog study sought to evaluate guided bone regeneration (GBR) in peri-implant defects following implantation of beta-tricalcium phosphate (beta-TCP) with and without osteoinductive recombinant human growth/differentiation factor-5 (rhGDF-5). MATERIALS AND METHODS: In five beagle dogs, all mandibular premolars and the first molar were extracted. After 2 months, six buccolingual critical-size defects were created, and an implant was inserted into the center of each defect. One defect was filled with beta-TCP coated with rhGDF-5 (600 microg/g beta-TCP) and covered with a titanium-reinforced e-PTFE membrane (GDF group). A second defect received the same treatment, but pure uncoated beta-TCP was used (TCP group). A third defect was filled with beta-TCP mixed with autograft and not protected with a membrane (control group). The remaining three defects were filled with other biomaterials. After 2 months, total new bone area, regenerated bone height, and residual amount of beta-TCP were determined histomorphometrically. RESULTS: All implants osseointegrated. One membrane in each group became exposed. Mean new bone area for GDF, TCP, and control sites was 43.9 +/- 18.7 mm2, 32.3 +/- 16.1 mm2, and 13.1 +/- 4.0 mm2, respectively, with a significant difference between GDF and control groups. Mean regenerated bone height was 103.8 +/- 29.7%, 75.4 +/- 36.6%, and 67.2 +/- 19.1% for the GDF, TCP, and control groups, respectively. Mean residual matrix volumes were 25.9 +/- 13.6%, 30.0 +/- 13.0%, and 13.4 +/- 6.5%, respectively. Membrane protection of peri-implant defects filled with beta-TCP resulted in a stronger effect on bone regeneration, although this was not statistically significant. The most pronounced regenerative results were achieved in rhGDF-5/beta-TCP filled membrane-protected defects. CONCLUSION: Delivery of rhGDF-5 on beta-TCP might have the potential to enhance the results of GBR in peri-implant defects.
Assuntos
Regeneração Óssea/efeitos dos fármacos , Implantes Dentários , Materiais Dentários , Fator 5 de Diferenciação de Crescimento/uso terapêutico , Regeneração Tecidual Guiada/instrumentação , Hormônio do Crescimento Humano/uso terapêutico , Mandíbula/cirurgia , Membranas Artificiais , Titânio , Perda do Osso Alveolar/cirurgia , Processo Alveolar/patologia , Animais , Materiais Biocompatíveis/uso terapêutico , Substitutos Ósseos/uso terapêutico , Transplante Ósseo , Fosfatos de Cálcio/uso terapêutico , Cães , Feminino , Humanos , Mandíbula/patologia , Osseointegração/fisiologia , Politetrafluoretileno/química , Distribuição Aleatória , Proteínas RecombinantesRESUMO
OBJECTIVES: The vertical location of the implant-abutment connection influences the periimplant bone morphology. It is unknown, however, whether different microgap configurations cause different bone reactions. Therefore, in this study the bone morphologies of two different implant systems were compared. MATERIAL AND METHODS: Three months after tooth extraction in eight mongrel dogs, two grit-blasted screw implants with internal Morse taper connection (ANK group) were placed on one side whereas the contralateral side received two oxidized screw implants with external hex (TIU group). One implant on each side was placed level with the bone (equicrestal), the second implant was inserted 1.5 mm below bone level (subcrestal). After 3 months the implants were uncovered. Three months after stage two surgery, histometrical evaluations were performed in order to assess the periimplant bone levels (PBL), the first bone-to-implant contact points (BICP), the width (HBD) and the steepness (SLO) of the bone defect. RESULTS: All implants osseointegrated clinically and histologically. Bone overgrowth of the microgap was seen in ANK implants only. No significant differences between ANK and TIU could be detected in neither vertical position for PBL and BICP. However, a tendency in favor of ANK was visible when the implants were placed subcrestally. In the parameters HBD (ANK equicrestal -0.23 mm; TIU equicrestal -0.51 mm; ANK subcrestal +0.19 mm; TIU subcrestal -0.57 mm) and SLO (ANK equicrestal 35.36 degrees; TIU equicrestal 63.22 degrees; ANK subcrestal 20.40 degrees; TIU subcrestal 44.43 degrees) more pronounced and significant differences were noted. CONCLUSIONS: Within the limits of this study, it is concluded that different microgap designs cause different shapes and sizes of the periimplant ('dish-shaped') bone defect in submerged implants both in equicrestal and subcrestal positions.
Assuntos
Perda do Osso Alveolar/etiologia , Dente Suporte , Implantação Dentária Endóssea/métodos , Implantes Dentários , Planejamento de Prótese Dentária/efeitos adversos , Animais , Implantação Dentária Endóssea/efeitos adversos , CãesRESUMO
Precision telescopic attachments allow for rigid connection between removable prostheses and abutments. However, it is still unknown whether implants can bear similar long-term loading forces as teeth when telescopic crowns are used as retention devices. It was the aim of this prospective clinical study to observe maxillary removable partial dentures that were retained by telescopic crowns on two endosseous implants in the canine regions. In a control group, identical dentures were fabricated that were retained by telescopic crowns on the maxillary canines. The implant group consisted of 14 patients, and the control group included 8 patients. Mean observation time of the prostheses was 25.6 months. Radiographic bone levels and periodontal parameters did not reveal specific differences between the two groups. However, five implants failed, and there were no failures in the control group. Survival rates were 48.9% for the implant group and 100% for the control group, with a significant difference between the two groups. Within the limits of this study, it is concluded that the telescopic connection might be too rigid (thus delivering overloading) for two single implants in the canine region of the maxilla supporting a removable denture.
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Perda do Osso Alveolar/etiologia , Implantes Dentários para Um Único Dente/efeitos adversos , Prótese Dentária Fixada por Implante , Falha de Restauração Dentária , Prótese Parcial Removível , Perda do Osso Alveolar/diagnóstico por imagem , Coroas , Dente Canino , Dente Suporte , Análise do Estresse Dentário , Retenção de Dentadura/instrumentação , Feminino , Humanos , Estimativa de Kaplan-Meier , Masculino , Maxila , Pessoa de Meia-Idade , Estudos Prospectivos , RadiografiaRESUMO
BACKGROUND: Zirconia might be an alternative material to titanium for dental implant fabrication. The aim of the present study was to investigate the histological behavior (osseointegration) of loaded zirconia implants in an animal model and to compare it with the behavior of titanium implants. METHODS: Five months after extraction of the upper anterior teeth, 12 custom-made titanium implants (control group) and 12 custom-made zirconia implants (test group) were inserted in the extraction sites in six monkeys. Before insertion, the titanium implant surfaces were sandblasted with Al2O3 and subsequently acid-etched. The zirconia implants were only sandblasted. Six months following implant insertion, impressions were taken for the fabrication of single crowns. A further 3 months later, nonprecious metal crowns were inserted. Five months after insertion of the crowns, the implants with the surrounding hard and soft tissues were harvested, histologically prepared, and evaluated under the light microscope regarding the peri-implant soft tissue dimensions and mineralized bone-to-implant contact. RESULTS: No implant was lost during the investigational period. The mean height of the soft peri-implant tissue cuff was 5 mm around the titanium implants and 4.5 mm around the zirconia implants. No statistically significant differences were found in the extent of the different soft tissue compartments. The mean mineralized bone-to-implant contact after 9 months of healing and 5 months of loading amounted to 72.9% (SD: 14%) for the titanium implants and to 67.4% (SD: 17%) for the zirconia implants. There was no statistically significant difference between the different implant materials. CONCLUSION: Within the limits of this animal experiment, it can be concluded that the custom-made zirconia implants osseointegrated to the same extent as custom-made titanium control implants and show the same peri-implant soft tissue dimensions.
Assuntos
Implantes Dentários , Planejamento de Prótese Dentária , Osseointegração/fisiologia , Titânio/química , Zircônio/química , Condicionamento Ácido do Dente , Abrasão Dental por Ar , Óxido de Alumínio/química , Animais , Tecido Conjuntivo/patologia , Coroas , Prótese Dentária Fixada por Implante , Inserção Epitelial/patologia , Gengiva/patologia , Processamento de Imagem Assistida por Computador , Macaca fascicularis , Maxila/patologia , Maxila/cirurgia , Modelos Animais , Fatores de Tempo , Alvéolo Dental/patologia , Alvéolo Dental/cirurgiaRESUMO
BACKGROUND: In cases of reduced alveolar bone height, implants of short length (10 mm or less) may be employed although there is a perceived risk that because of their small stature they will be unable to tolerate occlusal loads and will fail to osseointegrate. PURPOSE: This report describes an analysis of prospective multicenter clinical studies evaluating the risk for failure of short-length implants, comparing dual acid-etched (DAE) Osseotite implants (Implant Innovations, Inc., Palm Beach Gardens, FL, USA) to machined-surfaced implants. MATERIALS AND METHODS: Admission criteria were the same for both data sets. Baseline variables of demographics including age, gender and smoking status, bone quality, location, implant dimensions, and types of prostheses were compared to ensure balance among groups. Cumulative survival rates (CSRs) were calculated with the Kaplan-Meier estimator. RESULTS: The implant data included 2294 implants for the DAE series and 2597 implants for the machined-surfaced series. Patient demographics showed similar percentages of occurrence for all variables. The distributions of implants between short- and standard-length data sets for baseline variables including width, location, and restorative type were similar, qualifying these data sets for comparison of the independent variable of length. Overall, there was a 2.2% difference in 5-year CSRs between the machined-surfaced short- and the standard-length implants. For these implants a 7.1% difference was observed in the posterior maxilla and an 8.5% difference in the anterior maxilla. For DAE implants the overall difference between "standards" and "shorts" was 0.7%, which is not statistically significant. CONCLUSION: In this analysis the difference in CSRs between short- and standard-length implants was greater for machined-surfaced implants than for DAE implants.
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Implantação Dentária Endóssea/instrumentação , Implantes Dentários , Planejamento de Prótese Dentária , Falha de Restauração Dentária , Adulto , Idoso , Implantação Dentária Endóssea/estatística & dados numéricos , Implantes Dentários/estatística & dados numéricos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Osseointegração , Estudos Prospectivos , Medição de Risco , Estresse Mecânico , Propriedades de Superfície , Análise de Sobrevida , Fatores de Tempo , Resultado do TratamentoRESUMO
PURPOSE: In this prospective multicenter clinical study, 1,179 3i standard threaded and self-tapping implants were followed for up to 6 years and monitored according to established success criteria. MATERIALS AND METHODS: A total of 493 patients (240 men and 253 women) with a mean age of 45.1 years at implant surgery were enrolled at 6 research centers after being screened for exclusion criteria. Implants were placed according to a 2-stage surgical protocol with a minimum of 4 months of submerged healing in the mandible and 6 months in the maxilla. Restorations included 633 prostheses, the majority of which were fixed partial dentures in the posterior mandible or maxilla or single-tooth replacements in the anterior maxilla. RESULTS: One hundred four implants (8.8%) did not meet success criteria and were designated as failures, and 222 implants (18.8%) were lost to follow-up. The cumulative success rate according to life table methods was 91.1% at 6 years. DISCUSSION: Sixty percent of the failed implants were short (< or = 10 mm long), and their cumulative success rate as a group at 6 years was 89.0%, compared to 93.1% for longer implants (P < .05). Thirty-three percent of all failures were implants placed in the posterior maxilla, for a 5-year cumulative success rate of 87.4%. CONCLUSION: It appears that limited bone dimensions and poor-quality bone have an impact on the performance of these machined-surface implants.
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Implantes Dentários , Planejamento de Prótese Dentária , Densidade Óssea , Implantação Dentária Endóssea/métodos , Implantes Dentários para Um Único Dente , Prótese Dentária Fixada por Implante , Falha de Restauração Dentária , Prótese Parcial Fixa , Feminino , Seguimentos , Humanos , Tábuas de Vida , Masculino , Mandíbula/cirurgia , Maxila/cirurgia , Pessoa de Meia-Idade , Índice Periodontal , Estudos Prospectivos , Propriedades de Superfície , Análise de Sobrevida , Resultado do TratamentoRESUMO
Treatment of juvenile patients with a missing maxillary incisor is difficult, because an implant cannot be placed until growth is completed. The other minimally invasive alternatives are also problematic: Removable dentures are rarely accepted by juvenile patients, and the conventional resin-bonded fixed partial denture often provides a poor esthetic result because the metal retainer causes the abutment teeth to lose their natural translucency and to become grayish. Moreover, the alveolar ridge defect makes it easy to identify the prosthesis in the pontic area. The present case report describes the prosthetic treatment of a juvenile patient who had lost a maxillary incisor to trauma. To avoid the disadvantages of conventional therapies, subepithelial connective tissue was grafted to reshape the alveolar ridge. The space was closed with an all-ceramic resin-bonded fixed partial denture.
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Cerâmica , Planejamento de Dentadura , Prótese Adesiva , Adolescente , Alveoloplastia , Cerâmica/química , Tecido Conjuntivo/transplante , Dente Suporte , Colagem Dentária , Feminino , Gengiva/transplante , Humanos , Incisivo/lesões , Maxila , Perda de Dente/reabilitaçãoRESUMO
Failure of dental implants to achieve osseointegration is often attributed to patient baseline variables, such as smoking. This meta-analysis examines outcomes of clinical studies that monitored the performance of machined-surfaced and Osseotite, implants; the analysis also isolates the effect of smoking. The implant data for the machined-surfaced implants are derived from three prospective multicenter studies (n = 2,614) and from six prospective studies (n = 2,274) for the Osseotite implants. All implant placement surgeries followed a two-stage surgical approach with an unloaded healing period of 4 to 6 months. An evaluation of the data sets (i.e., smokers vs nonsmokers) was first performed to determine the existence of imbalance in baseline variables, including patient demographics, bone quality, location, dimensions, and types of prostheses. Analysis of the distributions of these baseline variables showed similar proportionalities and therefore qualified the data sets for comparison of the cumulative success rates (CSR) of the implants on the basis of smoking. For the 2,117 nonsmoking, machined-surfaced implants, the 3-year CSR is 92.8%; for the 492 implants in the smoking group, the CSR is 93.5%. The 3-year CSR for 1,877 nonsmoking Osseotite implants is 98.4%; for the 397 smoking implants it is 98.7%. No difference is observed between the smoking groups and the nonsmoking groups in these patient populations. There is, however, a clinically relevant difference observed between the two implant types.
Assuntos
Implantes Dentários , Planejamento de Prótese Dentária , Falha de Restauração Dentária , Fumar , Ensaios Clínicos como Assunto , Retenção em Prótese Dentária , Humanos , Tábuas de Vida , Osseointegração , Fatores de Risco , Propriedades de SuperfícieRESUMO
PURPOSE: To quantify the cement remnants on titanium and zirconia abutment analogs after cement removal by resin and steel scalers. MATERIALS AND METHODS: Defined areas of titanium or zirconia cylindric samples were covered with thin cement rings of zinc oxide phosphate (ZOP), glass ionomer (GIC), carboxylate (CAB), zinc oxide-eugenol (ZOE), or zinc oxide-eugenol-free (ZOEF). The cements were mixed with liquid-to-powder ratios of 50%, 75%, 100%, and 150% of powder. After setting and aging by thermocycling, each specimen was scaled by a blinded, trained clinician. Standardized digital photos of the scaled areas were analyzed according to a four-point classification scheme for remnants, and the results were analyzed statistically. RESULTS: The main effects of the independent variables "cement type," "abutment material," and "scaler" showed statistically significant differences for all variables. Such differences were also found with regard to the interactions of the variables "cement type" and "material" as well as for the type of cement and scaler. The extent of remnants after scaling differed significantly between titanium and zirconia. Steel scalers achieved statistically significantly better cleaning than resin scalers. The powder-to-liquid ratio of all luting agents significantly influenced the extent of cement surplus after scaling. ZOEF was the only type of cement that could be more successfully removed from titanium than from zirconia. CONCLUSIONS: Nearly complete removal of ZOE could be achieved. This luting agent was not as sensitive to aberrant mixing ratios or to resin or steel scaling as the other types of cement. With the exception of ZOEF, zirconia surfaces were easier to clean. After removal of most of the remnant, some cements showed a barely visible thin greasy or powdery layer.
Assuntos
Dente Suporte , Cimentos Dentários/química , Materiais Dentários/química , Raspagem Dentária/instrumentação , Titânio/química , Zircônio/química , Desenho de Equipamento , Cimentos de Ionômeros de Vidro/química , Humanos , Teste de Materiais , Plásticos/química , Cimento de Policarboxilato/química , Método Simples-Cego , Aço/química , Propriedades de Superfície , Temperatura , Fatores de Tempo , Água/química , Óxido de Zinco/química , Cimento de Óxido de Zinco e Eugenol/química , Cimento de Fosfato de Zinco/químicaRESUMO
This study aimed to histomorphometrically evaluate the soft tissue reactions of one-piece zirconia implants versus titanium implants in regard to their insertion depth. Four one-piece implants of identical geometry were inserted on each side of six mongrel dogs: an uncoated zirconia implant, a zirconia implant coated with a calcium liberating titanium oxide, a titanium implant, and an experimental implant made of a synthetic material. Using a split-mouth design, they were inserted in both submerged and nonsubmerged healing modes. After 4 months, dissected blocks were stained with toluidine blue to histologically assess the marginal portion of the implant mucosa, apical extension of the barrier epithelium, and margin level of bone-to-implant contact. The inflammation status at the crestal part of the implant was assessed as well. The histomorphology presented the typical soft tissue configuration of barrier epithelium and connective tissue near the bone-to-implant contact. Histomorphometrically, the length of the barrier epithelium did not differ significantly concerning material type or healing modality. Furthermore, the inflammation signs were higher with nonsubmerged implants. The submerged uncoated zirconia implants, however, showed few signs of inflammation. Within the limits of this study, it is concluded that uncoated and coated zirconia implants are capable of establishing sufficient soft tissue configurations that are comparable to those of titanium implants.
Assuntos
Implantação Dentária Endóssea , Implantes Dentários , Planejamento de Prótese Dentária , Cicatrização/fisiologia , Animais , Materiais Revestidos Biocompatíveis , Cães , Implantes Experimentais , Osseointegração , Titânio , ZircônioRESUMO
PURPOSE: The vertical location of the implant-abutment connection influences the subsequent reaction of the peri-implant bone. It is not known, however, whether any additional influence is exerted by different microgap configurations. Therefore, the radiographic bone reactions of two different implant systems were monitored for 6 months. MATERIALS AND METHODS: In eight mongrel dogs, two implants with an internal Morse-taper connection (INT group) were placed on one side of the mandible; the contralateral side received two implants with an external-hex connection (EXT group). On each side, one implant was aligned at the bone level (equicrestal) and the second implant was placed 1.5 mm subcrestal. Healing abutments were placed 3 months after submerged healing, and the implants were maintained for another 3 months without prosthetic loading. At implant placement and after 1, 2, 3, 4, 5, and 6 months, standardized radiographs were obtained, and peri-implant bone levels were measured with regard to microgap location and evaluated statistically. RESULTS: All implants osseointegrated clinically and radiographically. The overall mean bone loss was 0.68 ± 0.59 mm in the equicrestal INT group, 1.32 ± 0.49 mm in the equicrestal EXT group, 0.76 ± 0.49 mm in the subcrestal INT group, and 1.88 ± 0.81 mm in the subcrestal EXT group. The differences between the INT and EXT groups were statistically significant (paired t tests). The first significant differences between the internal and external groups were seen at month 1 in the subcrestal groups and at 3 months in the equicrestal groups. Bone loss was most pronounced in the subcrestal EXT group. CONCLUSIONS: Within the limits of this study, different microgap configurations can cause different amounts of bone loss, even before prosthetic loading. Subcrestal placement of a butt-joint microgap design may lead to more pronounced radiographic bone loss.
Assuntos
Perda do Osso Alveolar/diagnóstico por imagem , Projeto do Implante Dentário-Pivô , Implantes Dentários , Adaptação Marginal Dentária , Processo Alveolar/diagnóstico por imagem , Animais , Dente Pré-Molar , Dente Suporte , Planejamento de Prótese Dentária , Cães , Mandíbula/diagnóstico por imagem , Mandíbula/cirurgia , Dente Molar , Osseointegração/fisiologia , Osteotomia/métodos , Radiografia , Propriedades de Superfície , Fatores de Tempo , Alvéolo Dental/diagnóstico por imagem , Alvéolo Dental/cirurgiaRESUMO
PURPOSE: The implant-abutment connection (microgap) influences the peri-implant bone morphology. However, it is unclear if different microgap configurations additionally modify bone reactions. This preliminary study aimed to radiographically monitor peri-implant bone levels in two different microgap configurations during 3 months of nonsubmerged healing. MATERIALS AND METHODS: Six dogs received two implants with internal Morse taper connection (INT group) on one side of the mandible and two implants with external-hex connection (EXT group) on the other side. One implant on each side was positioned at bone level (equicrestal); the second implant was inserted 1.5 mm below the bone crest (subcrestal). Healing abutments were attached directly after implant insertion, and the implants were maintained for 3 months without prosthetic loading. At implant placement and 1, 2, and 3 months, standardized radiographs were taken to monitor peri-implant bone levels. RESULTS: All implants osseointegrated. A total bone loss of 0.48 ± 0.66 mm was measured in the equicrestal INT group, 0.69 ± 0.43 mm in the equicrestal EXT group, 0.79 ± 0.93 mm in the subcrestal INT group, and 1.56 ± 0.53 mm in the subcrestal EXT group (P > .05, paired t tests). Within the four groups, bone loss over time became significantly greater in the EXT groups than in the INT groups. The greatest bone loss was noted in the subcrestal EXT group. CONCLUSION: Within the limits of this animal study, it seems that even without prosthetic loading, different microgap configurations exhibit different patterns of bone loss during nonsubmerged healing. Subcrestal positioning of an external butt joint microgap may lead to faster radiographic bone loss.
Assuntos
Perda do Osso Alveolar/etiologia , Dente Suporte/efeitos adversos , Implantação Dentária Endóssea/métodos , Implantes Dentários/efeitos adversos , Planejamento de Prótese Dentária/efeitos adversos , Perda do Osso Alveolar/diagnóstico por imagem , Animais , Implantação Dentária Endóssea/efeitos adversos , Cães , Implantes Experimentais , RadiografiaRESUMO
OBJECTIVES: Application of the guided tissue regeneration (GTR) principle and utilization of enamel matrix derivative (EMD) have both been shown to result in periodontal regeneration. While clinical investigations have demonstrated that the use of a microsurgical concept in combination with the GTR technique positively affects the percentage of primary closure and the amount of tissue preservation, no such information is available for EMD-treated periodontal defects. It was the aim of the present investigation to assess the clinical effect of the microsurgical access flap and EMD treatment with an emphasis on the evaluation of early wound healing. MATERIAL AND METHODS: Eleven patients displaying at least one pair of intrabony periodontal defects with an intrabony component of > or =3 mm participated in the study. At baseline and at 6 and 12 months after surgery, the following clinical parameters were assessed by a blinded examiner: oral hygiene status (API), gingival inflammation (BOP), probing pocket depth (PPD), clinical attachment level (CAL) and gingival recession (GR). Defects were randomly assigned to test or control treatment, which both consisted of a microsurgical access flap procedure designed for maximum tissue preservation. The exposed root surfaces of the test sites were conditioned with a 24% EDTA gel followed by EMD (Emdogain(R)) application. Primary flap closure was achieved by a 2-layered suturing technique. Postoperative healing was evaluated by a newly introduced early wound-healing index (EHI) at 1 and 2 weeks after surgery. RESULTS: Both test and control treatment resulted in a statistically significant mean CAL gain of 2.8 and 2.0 mm at 6 months, and 3.6 and 1.7 mm at 12 months, respectively (p<0.05). Differences in CAL gain between the two treatment modalities were statistically significant at both time points (p<0.05). Additional GR values after 12 months averaged 0.3 and 0.4 mm for test and control sites, respectively, and did not reach statistical significance (p> or =0.05). Two weeks after surgery, primary closure was maintained in 89% of the test sites and in 96% of the control sites. CONCLUSION: Both treatment modalities using the microsurgical flap procedure resulted in a high percentage of primary flap closure and maximum tissue preservation. In terms of PPD reduction and CAL gain, the combination with EMD application appeared to be superior to the microsurgical access flap alone.
Assuntos
Perda do Osso Alveolar/tratamento farmacológico , Perda do Osso Alveolar/cirurgia , Proteínas do Esmalte Dentário/uso terapêutico , Procedimentos Cirúrgicos Bucais/métodos , Adulto , Análise de Variância , Índice de Placa Dentária , Feminino , Retração Gengival/tratamento farmacológico , Retração Gengival/cirurgia , Humanos , Masculino , Microcirurgia/métodos , Pessoa de Meia-Idade , Perda da Inserção Periodontal/tratamento farmacológico , Perda da Inserção Periodontal/cirurgia , Índice Periodontal , Estudos Prospectivos , Método Simples-Cego , Retalhos Cirúrgicos , CicatrizaçãoRESUMO
Implant sites with low bone content have exhibited lower implant survival rates than dense bone areas. Alterations of the implant surface seem to influence the bone-to-implant contact rate and may have an impact on implant failure rates in such sites. It was the objective of this animal study to histomorphometrically compare two different implant surfaces in so-called poor bone quality sites. All premolars on one side of the mandible were extracted in five fox hounds. After a healing time of 8 months, four screw-type implants (two with a machined surface (ICE group) and two with a double acid-etched (Osseotite) surface (OSS group)) were inserted into the mandible. Upon insertion, the implant apex was located in the 'hollow' part of the dog mandible, where the bone content is low. After 4 months healing, histomorphometric evaluations were performed. All implants osseointegrated clinically and histologically. Periapical density measurements revealed similar bone contents in both groups (ICE 49.9+/-16.7%, OSS 52.2+/-8.4%; P>0.05). Despite these similar amounts of bone content in the apical area around the implant, the Osseotite implant surface had a significantly higher bone-to-implant contact rate than the machined surface (OSS 62.9+/-12.4%, ICE 39.5+/-13.0%; P<0.01). It is concluded from this animal experiment that, in poor bone quality sites, an implant with an Osseotite surface can achieve a significantly higher bone-to-implant contact compared to a machined surface.