Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport.

Chua, Geok-Lin; Tan, Bryan C; Loke, Randy Y J; He, Menglan; Chin, Cheen-Fei; Wong, Bernice H; Kuk, Alvin C Y; Ding, Mei; Wenk, Markus R; Guan, Lan; Torta, Federico; Silver, David L.

Proc Natl Acad Sci U S A ; 120(10): e2215290120, 2023 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-36848557

2.

Diacylglycerol at the inner nuclear membrane fuels nuclear envelope expansion in closed mitosis.

Foo, Sherman; Cazenave-Gassiot, Amaury; Wenk, Markus R; Oliferenko, Snezhana.

J Cell Sci ; 136(3)2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-36695178

3.

Lipidomics: new tools and applications.

Wenk, Markus R.

Cell ; 143(6): 888-95, 2010 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-21145456

4.

Destabilization of ß Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.

Zheng, Xiaofeng; Ho, Qing Wei Calvin; Chua, Minni; Stelmashenko, Olga; Yeo, Xin Yi; Muralidharan, Sneha; Torta, Federico; Chew, Elaine Guo Yan; Lian, Michelle Mulan; Foo, Jia Nee; Jung, Sangyong; Wong, Sunny Hei; Tan, Nguan Soon; Tong, Nanwei; Rutter, Guy A; Wenk, Markus R; Silver, David L; Berggren, Per-Olof; Ali, Yusuf.

Proc Natl Acad Sci U S A ; 119(11): e2113074119, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35254894

5.

Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage.

He, Menglan; Kuk, Alvin C Y; Ding, Mei; Chin, Cheen Fei; Galam, Dwight L A; Nah, Jie Min; Tan, Bryan C; Yeo, Hui Li; Chua, Geok Lin; Benke, Peter I; Wenk, Markus R; Ho, Lena; Torta, Federico; Silver, David L.

Proc Natl Acad Sci U S A ; 119(40): e2210353119, 2022 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-36161949

6.

Integrative multi-omics database (iMOMdb) of Asian pregnant women.

Pan, Hong; Tan, Pei Fang; Lim, Ives Y; Huan, Jason; Teh, Ai Ling; Chen, Li; Gong, Min; Tin, Felicia; Mir, Sartaj Ahmad; Narasimhan, Kothandaraman; Chan, Jerry K Y; Tan, Kok Hian; Kobor, Michael S; Meikle, Peter J; Wenk, Markus R; Chong, Yap Seng; Eriksson, Johan G; Gluckman, Peter D; Karnani, Neerja.

Hum Mol Genet ; 31(18): 3051-3067, 2022 09 10.

Artigo em Inglês | MEDLINE | ID: mdl-35445712

7.

Mfsd2a-mediated lysolipid transport is important for renal recovery after acute kidney injury.

Loke, Randy Y J; Chin, Cheen Fei; Liang, Gao; Wong, Bernice H; Galam, Dwight L A; Tan, Bryan C; Chua, Geok-Lin; Minegishi, Shintaro; Morisawa, Norihiko; Sidorov, Iulia; Heijs, Bram; Titze, Jens; Wenk, Markus R; Torta, Federico; Silver, David L.

J Lipid Res ; 64(8): 100416, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37467896

8.

Myo-inositol alters the effects of glucose, leptin and insulin on placental palmitic acid and oleic acid metabolism.

Watkins, Oliver C; Pillai, Reshma Appukuttan; Selvam, Preben; Yong, Hannah E J; Cracknell-Hazra, Victoria K B; Sharma, Neha; Cazenave-Gassiot, Amaury; Bendt, Anne K; Godfrey, Keith M; Lewis, Rohan M; Wenk, Markus R; Chan, Shiao-Yng.

J Physiol ; 601(18): 4151-4169, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37602663

9.

The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis.

Wong, Bernice H; Mei, Ding; Chua, Geok Lin; Galam, Dwight L; Wenk, Markus R; Torta, Federico; Silver, David L.

J Biol Chem ; 298(3): 101709, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35150739

10.

Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study.

Chen, Li; Mir, Sartaj Ahmad; Bendt, Anne K; Chua, Esther W L; Narasimhan, Kothandaraman; Tan, Karen Mei-Ling; Loy, See Ling; Tan, Kok Hian; Shek, Lynette P; Chan, Jerry; Yap, Fabian; Meaney, Michael J; Chan, Shiao-Yng; Chong, Yap Seng; Gluckman, Peter D; Eriksson, Johan G; Karnani, Neerja; Wenk, Markus R.

BMC Med ; 21(1): 53, 2023 02 13.

Artigo em Inglês | MEDLINE | ID: mdl-36782297

11.

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss.

Mäe, Maarja A; He, Liqun; Nordling, Sofia; Vazquez-Liebanas, Elisa; Nahar, Khayrun; Jung, Bongnam; Li, Xidan; Tan, Bryan C; Chin Foo, Juat; Cazenave-Gassiot, Amaury; Wenk, Markus R; Zarb, Yvette; Lavina, Barbara; Quaggin, Susan E; Jeansson, Marie; Gu, Chengua; Silver, David L; Vanlandewijck, Michael; Butcher, Eugene C; Keller, Annika; Betsholtz, Christer.

Circ Res ; 128(4): e46-e62, 2021 02 19.

Artigo em Inglês | MEDLINE | ID: mdl-33375813

12.

Variability of the Plasma Lipidome and Subclinical Coronary Atherosclerosis.

Tan, Sock Hwee; Koh, Hiromi W L; Chua, Jing Yi; Burla, Bo; Ong, Ching Ching; Teo, Li San Lynette; Yang, Xiaoxun; Benke, Peter I; Choi, Hyungwon; Torta, Federico; Richards, A Mark; Wenk, Markus R; Chan, Mark Y.

Arterioscler Thromb Vasc Biol ; 42(1): 100-112, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34809445

13.

Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.

Vu, Thiet M; Ishizu, Ayako-Nakamura; Foo, Juat Chin; Toh, Xiu Ru; Zhang, Fangyu; Whee, Ding Ming; Torta, Federico; Cazenave-Gassiot, Amaury; Matsumura, Takayoshi; Kim, Sangho; Toh, Sue-Anne E S; Suda, Toshio; Silver, David L; Wenk, Markus R; Nguyen, Long N.

Nature ; 550(7677): 524-528, 2017 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-29045386

14.

Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes.

Wang, Jiexun; Liu, Jian-Jun; Gurung, Resham L; Liu, Sylvia; Lee, Janus; M, Yiamunaa; Ang, Keven; Shao, Yi Ming; Tang, Justin I-Shing; Benke, Peter I; Torta, Federico; Wenk, Markus R; Tavintharan, Subramaniam; Tang, Wern Ee; Sum, Chee Fang; Lim, Su Chi.

Diabetologia ; 65(12): 2146-2156, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35763031

15.

Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases.

Chai, Jin-Fang; Raichur, Suryaprakash; Khor, Ing Wei; Torta, Federico; Chew, Wee Siong; Herr, Deron Raymond; Ching, Jianhong; Kovalik, Jean-Paul; Khoo, Chin Meng; Wenk, Markus R; Tai, E Shyong; Sim, Xueling.

Hum Mol Genet ; 29(2): 189-201, 2020 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-31628463

16.

Population-based plasma lipidomics reveals developmental changes in metabolism and signatures of obesity risk: a mother-offspring cohort study.

Mir, Sartaj Ahmad; Chen, Li; Burugupalli, Satvika; Burla, Bo; Ji, Shanshan; Smith, Adam Alexander T; Narasimhan, Kothandaraman; Ramasamy, Adaikalavan; Tan, Karen Mei-Ling; Huynh, Kevin; Giles, Corey; Mei, Ding; Wong, Gerard; Yap, Fabian; Tan, Kok Hian; Collier, Fiona; Saffery, Richard; Vuillermin, Peter; Bendt, Anne K; Burgner, David; Ponsonby, Anne-Louise; Lee, Yung Seng; Chong, Yap Seng; Gluckman, Peter D; Eriksson, Johan G; Meikle, Peter J; Wenk, Markus R; Karnani, Neerja.

BMC Med ; 20(1): 242, 2022 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-35871677

17.

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

Blanc, Mathieu; Hsieh, Wei Yuan; Robertson, Kevin A; Kropp, Kai A; Forster, Thorsten; Shui, Guanghou; Lacaze, Paul; Watterson, Steven; Griffiths, Samantha J; Spann, Nathanael J; Meljon, Anna; Talbot, Simon; Krishnan, Kathiresan; Covey, Douglas F; Wenk, Markus R; Craigon, Marie; Ruzsics, Zsolts; Haas, Jürgen; Angulo, Ana; Griffiths, William J; Glass, Christopher K; Wang, Yuqin; Ghazal, Peter.

Immunity ; 38(1): 106-18, 2013 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-23273843

18.

Sex-Dependent Regulation of Placental Oleic Acid and Palmitic Acid Metabolism by Maternal Glycemia and Associations with Birthweight.

Watkins, Oliver C; Yong, Hannah E J; Mah, Tania Ken Lin; Cracknell-Hazra, Victoria K B; Pillai, Reshma Appukuttan; Selvam, Preben; Sharma, Neha; Cazenave-Gassiot, Amaury; Bendt, Anne K; Godfrey, Keith M; Lewis, Rohan M; Wenk, Markus R; Chan, Shiao-Yng.

Int J Mol Sci ; 23(15)2022 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-35955818

19.

Recommendations for good practice in MS-based lipidomics.

Köfeler, Harald C; Ahrends, Robert; Baker, Erin S; Ekroos, Kim; Han, Xianlin; Hoffmann, Nils; Holcapek, Michal; Wenk, Markus R; Liebisch, Gerhard.

J Lipid Res ; 62: 100138, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34662536

20.

Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy.

Wang, Wei; Xiang, Ping; Chew, Wee Siong; Torta, Federico; Bandla, Aishwarya; Lopez, Violeta; Seow, Wei Lun; Lam, Brenda Wan Shing; Chang, Jing Kai; Wong, Peiyan; Chayaburakul, Kanokporn; Ong, Wei-Yi; Wenk, Markus R; Sundar, Raghav; Herr, Deron R.

J Biol Chem ; 295(4): 1143-1152, 2020 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-31882542

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