Detalhe da pesquisa
1.
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists Part 1. The discovery of arylacetamides as viable replacements for the dihydropyrimidinone moiety of an HTS hit.
J Med Chem
; 50(16): 3870-82, 2007 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17668921
2.
Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits.
J Med Chem
; 50(16): 3883-90, 2007 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17668922
3.
Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists.
J Med Chem
; 48(8): 3076-9, 2005 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15828846