Detalhe da pesquisa
1.
Tyrosine urea muscarinic acetylcholine receptor antagonists: achiral quaternary ammonium groups.
Bioorg Med Chem Lett
; 22(23): 7087-91, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23099092
2.
Design, synthesis and structure-activity relationship of N-substituted tropane muscarinic acetylcholine receptor antagonists.
Bioorg Med Chem Lett
; 22(9): 3366-9, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22460029
3.
Azepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent.
Bioorg Med Chem Lett
; 21(15): 4409-15, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21733692
4.
Discovery of (3-endo)-3-(2-cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide as an efficacious inhaled muscarinic acetylcholine receptor antagonist for the treatment of COPD.
Bioorg Med Chem Lett
; 19(16): 4560-2, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19616944
5.
Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists.
Bioorg Med Chem Lett
; 19(1): 114-8, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19014886
6.
Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation.
ACS Infect Dis
; 5(10): 1738-1753, 2019 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31373203
7.
Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.
ACS Infect Dis
; 4(3): 349-359, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29275629
8.
Evaluation of potent and selective small-molecule antagonists for the CXCR2 chemokine receptor.
J Med Chem
; 47(6): 1319-21, 2004 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-14998320
9.
Discovery of novel 1-azoniabicyclo[2.2.2]octane muscarinic acetylcholine receptor antagonists.
J Med Chem
; 52(8): 2493-505, 2009 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19317446
10.
Design, synthesis, and structure-activity relationship of tropane muscarinic acetylcholine receptor antagonists.
J Med Chem
; 52(16): 5241-52, 2009 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19630384
11.
Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists.
Bioorg Med Chem Lett
; 17(22): 6066-9, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17911022
12.
3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists.
Bioorg Med Chem Lett
; 17(14): 3864-7, 2007 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17524641
13.
Comparison of N,N'-diarylsquaramides and N,N'-diarylureas as antagonists of the CXCR2 chemokine receptor.
Bioorg Med Chem Lett
; 17(6): 1713-7, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17236763
14.
N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors.
Bioorg Med Chem Lett
; 16(21): 5513-6, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16934456
15.
Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor.
Bioorg Med Chem Lett
; 14(17): 4375-8, 2004 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15357956
16.
A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit.
J Immunol
; 169(11): 6435-44, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12444152