Detalhe da pesquisa
1.
NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.
Cell
; 171(5): 1094-1109.e15, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149604
2.
Immune Cell Intolerance for Excess Cholesterol.
Immunity
; 45(6): 1186-1188, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002726
3.
Euglycemia is affected by stress defense factor hepatocyte NRF1, but not NRF2.
Biochem Biophys Res Commun
; 668: 96-103, 2023 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37245295
4.
Proteostasis in thermogenesis and obesity.
Biol Chem
; 401(9): 1019-1030, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32061163
5.
Coordinated regulation of protein synthesis and degradation by mTORC1.
Nature
; 513(7518): 440-3, 2014 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043031
6.
Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways.
Commun Biol
; 7(1): 623, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802487
7.
Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1869(6): 159512, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38761895
8.
Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload.
Cell Rep
; 42(4): 112399, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37060561
9.
HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2.
Front Physiol
; 14: 1212785, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501930
10.
Immunometabolic factors contributing to obesity-linked hepatocellular carcinoma.
Front Cell Dev Biol
; 10: 1089124, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36712976
11.
Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide.
J Biol Chem
; 284(44): 30372-82, 2009 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19748889
12.
Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload.
Cell Rep
; 42(7): 112872, 2023 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454293
13.
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.
Nat Med
; 24(3): 292-303, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400713
14.
Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic ß-cells.
Diabetes
; 62(1): 170-82, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22933114
15.
A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control.
PLoS One
; 5(3): e9590, 2010 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231880
16.
Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide.
J Biol Chem
; 284(16): 10764-73, 2009 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19233842