Detalhe da pesquisa
1.
Molecular Interactions Required for Activation of Complement Component C2 Include Exosites Located on the Serine Protease Domain of C1s and Mannose-Binding Lectin Associated Protease-2.
J Immunol
; 212(7): 1172-1177, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38372634
2.
Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease.
J Periodontal Res
; 58(3): 544-552, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37002616
3.
Protease-associated import systems are widespread in Gram-negative bacteria.
PLoS Genet
; 15(10): e1008435, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31613892
4.
Recruitment of Human C1 Esterase Inhibitor Controls Complement Activation on Blood Stage Plasmodium falciparum Merozoites.
J Immunol
; 198(12): 4728-4737, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28484054
5.
The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.
J Immunol
; 199(11): 3883-3891, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061764
6.
Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.
Blood
; 128(13): 1766-76, 2016 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27338096
7.
Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS.
PLoS Pathog
; 9(1): e1003117, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23326233
8.
The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.
J Biol Chem
; 288(31): 22399-407, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23792966
9.
Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.
J Biol Chem
; 288(22): 15571-80, 2013 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589288
10.
A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4.
J Biol Chem
; 288(22): 15821-9, 2013 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23592783
11.
Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s.
J Immunol
; 189(5): 2365-73, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22855709
12.
Total synthesis of homogeneous variants of hirudin P6: a post-translationally modified anti-thrombotic leech-derived protein.
Angew Chem Int Ed Engl
; 53(15): 3947-51, 2014 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24615823
13.
Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: two genes, five proteins and many functions?
Biochim Biophys Acta
; 1824(1): 253-62, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21664989
14.
S1 pocket of a bacterially derived subtilisin-like protease underpins effective tissue destruction.
J Biol Chem
; 286(49): 42180-42187, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21990366
15.
Discovery of amino acid motifs for thrombin cleavage and validation using a model substrate.
Biochemistry
; 50(48): 10499-507, 2011 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22050556
16.
Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI.
J Biol Chem
; 285(16): 11793-9, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20164177
17.
The lysine-specific gingipain of Porphyromonas gingivalis : importance to pathogenicity and potential strategies for inhibition.
Adv Exp Med Biol
; 712: 15-29, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21660656
18.
Characterization of a serine protease homologous to house dust mite group 3 allergens from the scabies mite Sarcoptes scabiei.
J Biol Chem
; 284(49): 34413-22, 2009 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19812030
19.
Mapping the binding site of C1-inhibitor for polyanion cofactors.
Mol Immunol
; 126: 8-13, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32717572
20.
Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor.
Mol Immunol
; 45(3): 670-7, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17709141