Detalhe da pesquisa
1.
Synthetic lethality between PAXX and XLF in mammalian development.
Genes Dev
; 30(19): 2152-2157, 2016 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798842
2.
USP4 Auto-Deubiquitylation Promotes Homologous Recombination.
Mol Cell
; 60(3): 362-73, 2015 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455393
3.
C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption.
Nat Commun
; 14(1): 5003, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591890
4.
ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib.
Cancer Res
; 82(6): 1140-1152, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35078817
5.
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.
Clin Cancer Res
; 28(20): 4536-4550, 2022 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921524
6.
Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development.
Mol Cancer Ther
; 20(9): 1614-1626, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34158341
7.
Combined PARP and ATR inhibition potentiates genome instability and cell death in ATM-deficient cancer cells.
Oncogene
; 39(25): 4869-4883, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32444694
8.
Publisher Correction: p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 30(5): 1506, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332041
9.
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Nat Commun
; 10(1): 5065, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699977
10.
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.
Sci Rep
; 8(1): 17891, 2018 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559450
11.
Author Correction: C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption.
Nat Commun
; 14(1): 7784, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012134
12.
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.
Nat Commun
; 8(1): 374, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28851861
13.
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 22(8): 861-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27376578
14.
Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity.
Nat Cell Biol
; 16(10): 1016-26, 1-8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25194926