Detalhe da pesquisa
1.
An Evolutionary Trace method defines functionally important bases and sites common to RNA families.
PLoS Comput Biol
; 16(3): e1007583, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32208421
2.
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2.
Proc Natl Acad Sci U S A
; 115(42): 10666-10671, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30266789
3.
Multimodal network diffusion predicts future disease-gene-chemical associations.
Bioinformatics
; 35(9): 1536-1543, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30304494
4.
Identification of a candidate therapeutic autophagy-inducing peptide.
Nature
; 494(7436): 201-6, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364696
5.
Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation.
Proc Natl Acad Sci U S A
; 113(13): 3539-44, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26979958
6.
UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures.
Nucleic Acids Res
; 44(D1): D308-12, 2016 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26590254
7.
Elucidation of G-protein and ß-arrestin functional selectivity at the dopamine D2 receptor.
Proc Natl Acad Sci U S A
; 112(22): 7097-102, 2015 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964346
8.
Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors.
J Biol Chem
; 290(5): 2870-8, 2015 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25519912
9.
Accounting for epistatic interactions improves the functional analysis of protein structures.
Bioinformatics
; 29(21): 2714-21, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24021383
10.
Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction.
BMC Bioinformatics
; 13: 235, 2012 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22978315
11.
HUMAN KINASES DISPLAY MUTATIONAL HOTSPOTS AT COGNATE POSITIONS WITHIN CANCER.
Pac Symp Biocomput
; 22: 414-425, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27896994
12.
DISCOVERY OF FUNCTIONAL AND DISEASE PATHWAYS BY COMMUNITY DETECTION IN PROTEIN-PROTEIN INTERACTION NETWORKS.
Pac Symp Biocomput
; 22: 336-347, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27896987
13.
Evolutionary action and structural basis of the allosteric switch controlling ß2AR functional selectivity.
Nat Commun
; 8(1): 2169, 2017 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29255305
14.
COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS.
Pac Symp Biocomput
; 21: 21-32, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26776170
15.
Prediction and redesign of protein-protein interactions.
Prog Biophys Mol Biol
; 116(2-3): 194-202, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24878423
16.
Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases.
Mol Cell Biol
; 34(3): 374-85, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24248599
17.
The use of evolutionary patterns in protein annotation.
Curr Opin Struct Biol
; 22(3): 316-25, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22633559