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1.
Gut ; 66(11): 1886-1899, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-28821598

RESUMO

This document represents the first position statement produced by the British Society of Gastroenterology and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland, setting out the minimum expected standards in diagnostic upper gastrointestinal endoscopy. The need for this statement has arisen from the recognition that while technical competence can be rapidly acquired, in practice the performance of a high-quality examination is variable, with an unacceptably high rate of failure to diagnose cancer at endoscopy. The importance of detecting early neoplasia has taken on greater significance in this era of minimally invasive, organ-preserving endoscopic therapy. In this position statement we describe 38 recommendations to improve diagnostic endoscopy quality. Our goal is to emphasise practices that encourage mucosal inspection and lesion recognition, with the aim of optimising the early diagnosis of upper gastrointestinal disease and improving patient outcomes.


Assuntos
Endoscopia do Sistema Digestório/normas , Gastroenteropatias/diagnóstico por imagem , Esôfago de Barrett/diagnóstico por imagem , Esôfago de Barrett/patologia , Doença Celíaca/diagnóstico por imagem , Doença Celíaca/patologia , Lista de Checagem , Competência Clínica , Endoscopia do Sistema Digestório/métodos , Gastroenteropatias/patologia , Neoplasias Gastrointestinais/diagnóstico por imagem , Neoplasias Gastrointestinais/patologia , Humanos , Consentimento Livre e Esclarecido/normas , Segurança do Paciente , Seleção de Pacientes , Lesões Pré-Cancerosas/diagnóstico por imagem , Lesões Pré-Cancerosas/patologia
2.
Ann Emerg Med ; 69(2): 184-191.e1, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27745763

RESUMO

STUDY OBJECTIVE: Seizures account for 1.2% of all emergency department (ED) visits, with 24% of those representing first-time seizures. Our primary goal is to determine whether obtaining an electroencephalogram (EEG) in the ED after a first-time seizure can identify individuals appropriate for initiation of anticonvulsant therapy on ED discharge. Our secondary goals are to determine the association of historical and clinical seizure features with epileptic EEGs and to determine the interobserver agreement for the EEG interpretation. METHODS: We conducted a prospective study including patients older than 17 years with either a first-time seizure or previous seizures without a previous EEG, all of whom were candidates for discharge home from the ED without antiepileptic drug treatment. We based seizure diagnosis on provider impression. We excluded patients with laboratory studies or neuroimaging deemed to be the seizure cause. EEG technicians performed a 30-minute EEG in the ED, which was immediately remotely interpreted by an epileptologist, who made a recommendation on antiepileptic drug initiation. We categorized EEGs as normal, abnormal but not epileptic, or epileptic. In accordance with duplicate EEG interpretation by a second, blinded epileptologist, we calculated interrater agreement for EEG interpretation and antiepileptic drug initiation. As a secondary analysis, according to questionnaires completed by patients and seizure observers, we explored the association of aura, focal symptoms, provocation, or historical risk factors with epilepsy. RESULTS: We enrolled 73 patients, 71 of whom had an EEG performed. All EEGs were performed within 11 hours of seizure, with an average of 3.85 hours. Twenty-four percent of patients (95% confidence interval 15% to 36%) received a diagnosis of epilepsy, and all began receiving antiepileptic drug therapy from the ED. Our final study sample size afforded only an exploratory analysis about an association between aura, focal onset, provocation, or historical risk factors with an epilepsy diagnosis. Weighted κ agreement for EEG interpretation was 0.69 (95% confidence interval 0.55 to 0.82). Of the 34 patients who followed up with an epileptologist, 9 had received a diagnosis of epilepsy in the ED, and none had antiepileptic drug medication stopped at initial follow-up. CONCLUSION: ED EEG performance in adults with first-time seizures results in a substantial yield of an epilepsy diagnosis and immediate initiation of antiepileptic drug treatment. A larger study is required to determine whether historical and clinical seizure features are associated with an ED epilepsy diagnosis.


Assuntos
Eletroencefalografia , Serviço Hospitalar de Emergência , Convulsões/diagnóstico , Adulto , Anticonvulsivantes/uso terapêutico , Feminino , Humanos , Masculino , Alta do Paciente , Estudos Prospectivos , Convulsões/tratamento farmacológico , Convulsões/fisiopatologia
3.
Clin Anat ; 21(6): 501-8, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18627103

RESUMO

The objective of this study was to assess the safety and accuracy of using common anatomic landmarks to guide the placement of needle electrodes into suboccipital muscles. Atrophic changes in suboccipital muscles have been reported in some patients who have tension-type headaches, and in some patients who have headaches resulting from whiplash-type injuries. These atrophic changes most likely result from disuse or denervation. Needle electromyography is a definitive technique for determining the cause of muscle atrophy, but requires that needle electrodes be inserted into the muscle. Suboccipital muscles present a challenge to the electromyographer in that they are physically small and are located in close proximity to one another. Atrophied muscles with fatty replacement and the presence of critical structures such as the vertebral artery further complicate the procedure. Using a standardized protocol, three investigators attempted blind needle insertions into each of the suboccipital muscles of eight embalmed cadavers. A dissector then assessed targeted muscle penetrations, final resting positions of the wires, and their proximity to critical structures. Eighty-one percent of 181 attempted insertions penetrated the targeted muscles: 83% for the rectus capitis posterior minor, 83% for the rectus capitis posterior major, 94% for the obliquus capitis superior, and 63% for the obliquus capitis inferior muscles, respectively. It was concluded that readily palpable external landmarks can be used to safely and reliably guide the insertion of needle electrodes into three of the four pairs of suboccipital muscles.


Assuntos
Eletromiografia/métodos , Músculos do Pescoço/anatomia & histologia , Idoso , Idoso de 80 Anos ou mais , Eletrodos , Feminino , Humanos , Masculino , Agulhas
4.
Hepatobiliary Pancreat Dis Int ; 5(3): 462-4, 2006 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16911951

RESUMO

BACKGROUND: Cholecystocolocutaneous fistula (CCCF) is a rare complication of gallstone disease resulting from spillage of gallstones from perforation of an empyema of the gallbladder, which can pose diagnostic dilemmas. We describe a patient, who presented initially with a swelling followed by discharging sinuses on her right flank where a diagnosis of CCCF was made and was treated surgically with satisfactory outcome. METHODS: A computed tomography (CT) scan showed an ill-defined soft tissue mass in the right subhepatic space and a fistulogram demonstrated passage of contrast into the gallbladder fossa and hepatic flexure of colon. At laparotomy, a cutaneous fistula containing two pigment stones led to the gallbladder fossa and hepatic flexure of colon. RESULTS: Debridement of infected granulation tissues which had replaced the gallbladder, closure of the cystic duct stump and colonic fistula followed by excision of the fistula tract led to complete resolution. CONCLUSIONS: CCCF is a rare complication of perforated gallbladder with spillage of calculi, and a fistulogram is helpful in establishing the diagnosis. This case highlights the importance of retrieving spilled stones following interventions in the gallbladder to prevent the complication.


Assuntos
Neoplasias do Colo/diagnóstico por imagem , Fístula/diagnóstico por imagem , Doenças da Vesícula Biliar/diagnóstico por imagem , Dermatopatias/diagnóstico por imagem , Idoso , Neoplasias do Colo/etiologia , Feminino , Fístula/etiologia , Doenças da Vesícula Biliar/complicações , Doenças da Vesícula Biliar/etiologia , Humanos , Dermatopatias/etiologia , Tomografia Computadorizada por Raios X
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