Detalhe da pesquisa
1.
Characterization of RNA driven structural changes in full length RIG-I leading to its agonism or antagonism.
Nucleic Acids Res
; 51(17): 9356-9368, 2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37486777
2.
Irrigated Crop Types Mapping in Tashkent Province of Uzbekistan with Remote Sensing-Based Classification Methods.
Sensors (Basel)
; 22(15)2022 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35957240
3.
Assessment of Climate Change and Human Activities on Vegetation Development in Northeast China.
Sensors (Basel)
; 22(7)2022 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408124
4.
The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.
Bioorg Med Chem
; 22(7): 2303-10, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24588962
5.
Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors.
Cell Rep
; 42(4): 112297, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961816
6.
Combining NMR and X-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors.
Top Curr Chem
; 317: 83-114, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-21647837
7.
The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases.
Respir Res
; 13: 30, 2012 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22475739
8.
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.
J Med Chem
; 65(7): 5675-5689, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332774
9.
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
J Med Chem
; 65(24): 16234-16251, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36475645
10.
Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI.
J Magn Reson Imaging
; 33(3): 603-14, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21563244
11.
Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation.
Respir Res
; 11: 126, 2010 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20849642
12.
An orally available non-nucleotide STING agonist with antitumor activity.
Science
; 369(6506)2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820094
13.
Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses.
J Pharmacol Exp Ther
; 327(3): 851-62, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18806126
14.
NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA.
J Biomol Screen
; 21(6): 579-89, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27028606
15.
Mast cell involvement in the adenosine mediated airway hyper-reactivity in a murine model of ovalbumin-induced lung inflammation.
Br J Pharmacol
; 145(7): 845-52, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15912130
16.
NMR screening in fragment-based drug design: a practical guide.
Methods Mol Biol
; 1263: 197-208, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25618347
17.
Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.
Protein Sci
; 12(12): 2757-67, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14627736
18.
Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications.
Adv Drug Deliv Rev
; 54(4): 547-70, 2002 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12052714
19.
Structure, biology, and therapeutic implications of pegylated interferon alpha-2b.
Curr Pharm Des
; 8(24): 2139-57, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12369859
20.
NMR-based approaches for lead discovery.
Curr Opin Drug Discov Devel
; 5(4): 630-47, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12197321