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Skin wounds accompanied by bacterial infections threaten human health, and conventional antibiotic treatments are ineffective for drug-resistant bacterial infections and chronically infected wounds. The development of non-antibiotic-dependent therapeutics is highly desired but remains a challenging issue. Recently, 2D silicene nanosheets with considerable biocompatibility, biodegradability, and photothermal-conversion performance have received increasing attention in biomedical fields. Herein, copper-containing nanoparticles-loaded silicene (Cu2.8O@silicene-BSA) nanosheets with triple enzyme mimicry catalytic (peroxidase, catalase, and oxidase-like) activities and photothermal function are rationally designed and fabricated for efficient bacterial elimination, angiogenesis promotion, and accelerated wound healing. Cu2.8O@silicene-BSA nanosheets display excellent antibacterial activity through synergistic effects of reactive oxygen species generated from multiple catalytic reactions, intrinsic bactericidal activity of released Cu2+ ions, and photothermal effects, achieving high antibacterial efficiencies on methicillin-resistant Staphylococcus aureus (MRSA) of 99.1 ± 0.7% in vitro and 97.2 ± 1.6% in vivo. In addition, Cu2.8O@silicene-BSA nanosheets exhibit high biocompatibility for promoting human umbilical vein endothelial cell (HUVEC) proliferation and angiogenic differentiation. In vivo experiments reveal that Cu2.8O@silicene-BSA nanosheets with synergistic photothermal/chemodynamic therapeutics effectively accelerate MRSA-infected wound healing by eliminating bacteria, alleviating inflammation, boosting collagen deposition, and promoting angiogenesis. This research presents a promising strategy to engineer photothermal-assisted nanozyme catalysis for bacteria-invaded wound healing.
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Infecções Bacterianas , Staphylococcus aureus Resistente à Meticilina , Humanos , Cobre , Bactérias , Cicatrização , Antibacterianos/farmacologia , Antibacterianos/uso terapêuticoRESUMO
Ultralong nanowires with ultrahigh aspect ratios exhibit high flexibility, and they are promising for applications in various fields. Herein, a cadmium oleate precursor hydrothermal method is developed for the synthesis of ultralong nanowires of cadmium phosphate hydroxide. In this method, water-soluble cadmium salt is used as the cadmium source, water-soluble phosphate is used as the phosphorus source, and sodium oleate is adopted as a reactant to form cadmium oleate precursor and as a structure-directing agent. By using this method, ultralong nanowires of cadmium phosphate hydroxide are successfully synthesized using CdCl2, sodium oleate, and NaH2PO4 as reactants in an aqueous solution by hydrothermal treatment at 180 °C for 24 h. In addition, a new type of flexible fire-resistant inorganic paper with good electrical insulation performance is fabricated using ultralong nanowires of cadmium phosphate hydroxide. As an example of the extended application of this synthetic method, ultralong nanowires of cadmium phosphate hydroxide can be converted to ultralong CdS nanowires through a convenient sulfidation reaction. In this way, ultralong CdS nanowires are successfully synthesized by simple sulfidation of ultralong nanowires of cadmium phosphate hydroxide under mild conditions. The as-prepared ultralong nanowires of cadmium phosphate hydroxide are promising for applications as the precursors and templates for synthesizing other inorganic ultralong nanowires and have wide applications in various fields.
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Solar energy-driven water evaporation is a promising sustainable strategy to purify seawater and contaminated water. However, developing solar evaporators with high water evaporation rates and excellent salt resistance still faces a great challenge. Herein, inspired by the long-range ordered structure and water transportation capability of lotus stem, a biomimetic aerogel with vertically ordered channels and low water evaporation enthalpy for high-efficiency solar energy-driven salt-resistant seawater desalination and wastewater purification is developed. The biomimetic aerogel consists of ultralong hydroxyapatite nanowires as heat-insulating skeletons, polydopamine-modified MXene as a photothermal material with broadband sunlight absorption and high photothermal conversion efficiency, polyacrylamide, and polyvinyl alcohol as reagents to lower the water evaporation enthalpy and as glues to enhance the mechanical performance. The honeycomb porous structure, unidirectionally aligned microchannels, and nanowire/nanosheet/polymer pore wall endow the biomimetic aerogel with excellent mechanical properties, rapid water transportation, and excellent solar water evaporation performance. The biomimetic aerogel exhibits a high water evaporation rate (2.62 kg m-2 h-1 ) and energy efficiency (93.6%) under one sun irradiation. The superior salt-rejecting ability of the designed water evaporator enables stable and continuous seawater desalination, which is promising for application in water purification to mitigate the global water crisis.
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Security inks based on photoluminescent materials are mostly investigated for security applications, such as information encryption and decryption, anti-counterfeiting, and data storage. Although they are invisible to the naked eye under ambient light, they can be detected under ultraviolet or near-infrared light. Herein, a new kind of secret paper made from network-structured ultralong hydroxyapatite nanowires and cellulose fibers has been developed. White vinegar, a common cooking ingredient, is used as an invisible security ink. Covert information on the secret paper written with white vinegar is totally invisible under natural light, but it can be decrypted and clearly read after exposure to fire; the response time to fire is short (<10â s). The ways of writing on the secret paper are diverse by using various pens loaded with white vinegar.
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Efficient utilization of abundant solar energy for clean water generation is considered a sustainable and environment friendly approach to mitigate the global water crisis. For this purpose, this study reports a flexible fire-resistant photothermal paper by combining carbon nanotubes (CNTs) and fire-resistant inorganic paper based on ultralong hydroxyapatite nanowires (HNs) for efficient solar energy-driven water steam generation and water purification. Benefiting from the structural characteristics of the HN/CNT photothermal paper, the black CNT surface layer exhibits a high light absorbability and photothermal conversion capability, the HN-based inorganic paper acts as a thermal insulator with a high temperature stability, low thermal conductivity, and interconnected porous structure. By combining these advantages, high water evaporation efficiencies of 83.2% at 1 kW m-2 and 92.8% at 10 kW m-2 are achieved. In addition, the HN/CNT photothermal paper has a stable water evaporation capability during recycling and long-time usage. The promising potential of the HN/CNT photothermal paper for efficient production of drinkable water from both actual seawater and simulative wastewater samples containing heavy metal ions, dyes, and bacteria is also demonstrated. The highly flexible HN/CNT photothermal paper is promising for application in highly efficient solar energy-driven seawater desalination and wastewater purification.
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To date, the scaled-up production and large-area applications of superhydrophobic coatings are limited because of complicated procedures, environmentally harmful fluorinated compounds, restrictive substrates, expensive equipment, and raw materials usually involved in the fabrication process. Herein, the facile, low-cost, and green production of superhydrophobic coatings based on hydroxyapatite nanowire bundles (HNBs) is reported. Hydrophobic HNBs are synthesised by using a one-step solvothermal method with oleic acid as the structure-directing and hydrophobic agent. During the reaction process, highly hydrophobic C-H groups of oleic acid molecules can be attached in situ to the surface of HNBs through the chelate interaction between Ca2+ ions and carboxylic groups. This facile synthetic method allows the scaled-up production of HNBs up to about 8â L, which is the largest production scale of superhydrophobic paint based on HNBs ever reported. In addition, the design of the 100â L reaction system is also shown. The HNBs can be coated on any substrate with an arbitrary shape by the spray-coating technique. The self-cleaning ability in air and oil, high-temperature stability, and excellent mechanical durability of the as-prepared superhydrophobic coatings are demonstrated. More importantly, the HNBs are coated on large-sized practical objects to form large-area superhydrophobic coatings.
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The templated synthesis of hydroxyapatite (HAP) nanowires@metal-organic framework (MOF) core/shell nanofibers (named HAP@MIL-100(Fe) nanofibers) is demonstrated. The ultralong hydroxyapatite nanowires are adopted as a hard template for the nucleation and growth of MIL-100(Fe) (a typical MOF) through the layer-by-layer method. The Coulombic and chelation interactions between Ca2+ ions on the surface of the HAP nanowires and the COO- organic linkers of MIL-100(Fe) play key roles in the formation process. The as-prepared, water-stable HAP@MIL-100(Fe) nanofibers exhibit peroxidase-like activity toward the oxidation of different peroxidase substrates in the presence of H2 O2 , accompanied by a clear color change of the solution. Furthermore, a flexible, recyclable HAP@MIL-100(Fe) test paper is prepared successfully by using HAP@MIL-100(Fe) nanofibers as building blocks. A simple, low-cost, and sensitive colorimetric method for the detection of H2 O2 and glucose is established based on the as-prepared, flexible, recyclable HAP@MIL-100(Fe) test paper. More importantly, the HAP@MIL-100(Fe) test paper can be recovered easily for reuse by simply dipping in absolute ethanol for just 30â min, thus showing excellent recyclability. With its combination of advantages such as easy transportation, easy storage and use, rapid recyclability, light weight, and high flexibility, this HAP@MIL-100(Fe) test paper is promising for wide applications in various fields.
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Durapatita/química , Estruturas Metalorgânicas/química , Nanofibras/química , Nanofios/química , Peroxidase/química , Ácido Ascórbico/análise , Bioensaio/métodos , Cálcio/química , Glucose/análise , Peróxido de Hidrogênio/análise , Oxirredução , Tamanho da Partícula , Espectroscopia de Infravermelho com Transformada de Fourier/métodos , Propriedades de Superfície , Termogravimetria/métodos , Água/químicaRESUMO
A highly flexible and free-standing paper with high antibacterial activity made from silver nanoparticle (AgNP)-decorated ultralong hydroxyapatite nanowires (HAPNWs) is reported. The HAPNWs@AgNPs nanocomposites were obtained from a facile one-step solvothermal process and utilized for the construction of highly flexible and free-standing inorganic paper through a simple vacuum-filtration procedure. The structure and properties of the HAPNWs@AgNPs paper were characterized in detail. Scanning electron microscope (SEM) and transmission electron microscope (TEM) micrographs show that AgNPs are highly dispersed and stabilized in the nanocomposite and exhibit a narrow particle size distribution. The effects of the concentration of silver nitrate, solvothermal temperature and time on the product were systematically investigated. This method is simple, convenient and reproducible. The as-prepared HAPNWs@AgNPs paper shows long-time sustained silver-ion release, high antibacterial activity against both Gram-negative and Gram-positive bacteria, and good biocompatibility. Overall, this work provides a novel pathway for the preparation of a new type of highly flexible, free-standing and antibacterial inorganic paper made from silver nanoparticle-decorated hydroxyapatite nanowires for various applications, as a promising functional biomaterial.
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Antibacterianos/síntese química , Durapatita/química , Durapatita/síntese química , Nanopartículas Metálicas/química , Nanocompostos/química , Nanofios/química , Prata/química , Antibacterianos/química , Bactérias Gram-Positivas , Microscopia Eletrônica de TransmissãoRESUMO
Facile preparation of core-shell magnetic metal-organic framework nanospheres by a layer-by-layer approach is presented. The nanospheres have high surface area (285.89â cm(2) g(-1)), large pore volume (0.18â cm(3) g(-1)), two kinds of mesopores (2.50 and 4.72â nm), excellent magnetic responsivity (55.65â emu g(-1)), structural stability, and good dispersibility. The combination of porosity, hydrophobicity, and uniform magnetism was exploited for effective enrichment of peptides with simultaneous exclusion of high molecular weight proteins. The nanospheres were successfully applied in the selective enrichment of endogenous peptides in human serum.
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Nanosferas , Peptídeos/química , Fenômenos Magnéticos , Fenômenos FísicosRESUMO
A field sampling method based on magnetic core-shell silica nanoparticles was developed for field sampling and the enrichment of low concentrations of pesticides in aqueous samples. The magnetic nanoparticles could be easily extracted from water samples by a custom-made magnetic nanoparticle collector. The recovery of 15 mg of magnetic particles from a 500 mL water sample was 90.8%. Mixtures of seven pesticides spiked into pure water and pond water were used as marker samples to evaluate the field sampling method. The average recoveries at three levels of spiking were in the range 60.0-104.7% with relative standard deviations <7.1%. The proposed method has good linearity with a correlation coefficient >0.9990 in the concentration range 0.5-15 µg L(-1). The results of the analysis of a sample of poisoned pond water indicate that this method is fast, convenient and efficient for the field sampling and enrichment of pesticides in aqueous samples.
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Nanopartículas Metálicas/química , Praguicidas/química , Água/química , Fracionamento Químico/instrumentação , Fracionamento Químico/métodos , Monitoramento Ambiental , Fenômenos Magnéticos , Poluentes Químicos da Água/químicaRESUMO
Hydrazide chemistry is a powerful technique in glycopeptides enrichment. However, the low density of the monolayer hydrazine groups on the conventional hydrazine-functionalized magnetic nanoparticles limits the efficiency of glycopeptides enrichment. Herein, a novel magnetic nanoparticle grafted with poly(glycidyl methacrylate) (GMA) brushes was fabricated via reversible addition-fragmentation chain transfer (RAFT) polymerization, and a large amount of hydrazine groups were further introduced to the GMA brushes by ring-opening the epoxy groups with hydrazine hydrate. The resulting magnetic nanoparticles (denoted as Fe3O4@SiO2@GMA-NHNH2) demonstrated the high specificity of capturing glycopeptides from a tryptic digest of the sample comprising a standard non-glycosylated protein bovine serum albumin (BSA) and four standard glycoproteins with a weight ratio of 50 : 1, and the detection limit was as low as 130 fmol. In the analysis of a real complex biological sample, the tryptic digest of hepatocellular carcinoma, 179 glycosites were identified by the Fe3O4@SiO2@GMA-NHNH2 nanoparticles, surpassing that of 68 glycosites by Fe3O4@SiO2-single-NHNH2 (with monolayer hydrazine groups on the surface). It can be expected that the magnetic nanoparticles modified with hydrazine functionalized polymer brushes via RAFT technique will improve the specificity and the binding capacity of glycopeptides from complex samples, and show great potential in the analysis of protein glycosylation in biological samples.
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Glicopeptídeos/química , Hidrazinas/química , Magnetismo , Nanopartículas , Polímeros/química , Humanos , Limite de Detecção , Fígado/química , Neoplasias Hepáticas/química , Microscopia Eletrônica de Transmissão , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por MatrizRESUMO
Selective enrichment of glycopeptides from complicated biological samples is critical for glycoproteomics to obtain the structure and glycosylation information of glycoproteins using mass spectrometry (MS), which still remains a great challenge. Hydrophilic interaction chromatography (HILIC)-based strategies have been proposed for selective isolation of glycopeptides via the interactions between the glycan of glycopeptides and the matrices. However, the application of these methods is limited by the medium selectivity of HILIC matrices. In this study, hydrophilic metal-organic frameworks (MOFs) were fabricated and used as a HILIC matrix. The cross-linked CD-MOFs (LCD-MOFs) were facilely prepared with γ-cyclodextrin as ligand and possessed nano-sized cubic structure, superior hydrophilicity, and bio-compatibility. The LCD-MOFs performance for the selective enrichment of glycopeptides from the complex biological samples were investigated with a digested mixture of human immunoglobulin G (IgG) that was used as standard samples. In the selectivity assessment, the non-glycopeptides causing ion suppression to the glycopeptides were effectively removed, the signal of glycopeptides were enhanced significantly by LCD-MOFs, and twenty glycopeptides were identified with 67 fmol of IgG digest. In addition, the resulting LCD-MOFs demonstrated the lower detection limit (3.3 fmol) with a satisfactory recovery yield (84-103%) for glycopeptide enrichment from a digest of IgG. Furthermore, a promising protocol was developed for the selective enrichment of glycopeptides from mouse liver, and 344 unique N-glycosylation sites that mapped to 290 different glycoproteins were identified in a single MS run. The results clearly demonstrated that when used in a HILIC matrix, LCD-MOFs have great potential for identifying and enriching low-abundant glycopeptides in complex biological samples.
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Cromatografia de Afinidade , Glicopeptídeos/isolamento & purificação , Compostos Organometálicos/química , Animais , Glicopeptídeos/análise , Glicosilação , Humanos , Interações Hidrofóbicas e Hidrofílicas , Imunoglobulina G/metabolismo , Fígado/metabolismo , Camundongos , Nanoestruturas/química , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz , gama-Ciclodextrinas/químicaRESUMO
Solar energy-driven water evaporation technology is a promising, low-cost and sustainable approach to alleviate the global clean water shortage, but usually suffers from low water evaporation rate and severe salt deposition on the water evaporation surface. In this work, a hydrophilic bilayer photothermal paper-based three-dimensional (3D) cone flowing evaporator was designed and prepared for stable high-performance seawater desalination with excellent salt-rejecting ability. The as-prepared bilayer photothermal paper consisted of MXene (Ti3C2Tx) and HAA (ultralong hydroxyapatite nanowires, poly(acrylic acid), and poly(acrylic acid-2-hydroxyethyl ester)). The accordion-like multilayered MXene acted as the efficient solar light absorber, and ultralong hydroxyapatite (HAP) nanowires served as the thermally insulating and supporting skeleton with a porous networked structure. A siphon effect-driven unidirectional fluid transportation unit in the 3D cone flowing evaporator could guide the concentrated saline flowing away from the evaporating surface to prevent salt deposition on the evaporation surface, avoiding severe deterioration of the performance in solar water evaporation. Furthermore, combining high solar light absorption and high photothermal conversion efficiencies, low water evaporation enthalpy (1838⯱â¯11â¯Jâ¯g-1), and additional energy taken from the ambient environment, the as-prepared cone flowing evaporator exhibited a high water evaporation rate of 3.22⯱â¯0.20â¯kgâ¯m-2 h-1 for real seawater under one sun illumination (1â¯kWâ¯m-2), which was significantly higher than many values reported in the literature. This study provides an effective approach for designing high-performance solar energy-driven water evaporators for sustainable seawater desalination and wastewater purification.
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Lu'an Guapian (LAGP) tea is one of the most famous teas in China. However, research on its suitable processing varieties is still lacking. This study analyzed the quality of LAGP tea made from three different tea varieties, namely, 'Anhui1' (AH1), 'Quntizhong' (QTZ), and 'Shuchazao' (SCZ), using molecular sensory science and metabolomics techniques. The results showed that AH1 had a strong floral aroma and the strongest umami flavor, while QTZ had a distinct roasted aroma and a mellow taste. SCZ had a cooked corn-like aroma and the highest bitterness and astringency owing to the high tea polyphenol contents and low free amino acid contents. The study also identified 12 key aroma-active compounds, with trans-beta-ionone and 2-ethyl-3,5-dimethyl-pyrazine contributing the most to floral and roasted aromas, respectively. The results of this study provide a theoretical and practical basis for selecting and breeding high-quality varieties of LAGP tea and stabilizing its quality.
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Sparganosis is a rare parasitic infection caused by plerocercoid tapeworm larvae. We described a case of a 27-year-old man presenting with numbness in both legs and masses in the right lung and spine, initially thought to have spinal metastasis from lung cancer. However, after pathological and parasitological examinations, the patient was found to have spinal sparganosis, likely due to a history of consuming raw frogs. The patient was successfully treated with praziquantel, resulting in the recovery of muscle strength in his legs. This case highlights the importance of considering spinal sparganosis as a differential diagnosis in patients with spinal masses, especially those with a history of consuming raw or undercooked frogs. Accurate diagnosis and early treatment are crucial for managing this infection.
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Over-fired drying, a crucial process in the production of Lu'an Guapian (LAGP) tea, greatly enriches the tea's aroma. In this study, the aroma compounds of LAGP tea processed through pulley charcoal drying (PCD), roller drying (RD), roller-conveyor drying (RCD), and hot air drying (HD) were analyzed using gas chromatography-mass spectrometry. A subsequent analysis of aroma extraction dilution analysis and odor activity values revealed that (E)-ß-ionone, dimethyl sulfide, (E,E)-2,4-heptadienal, geraniol, linalool, benzeneacetaldehyde, coumarin, 2-ethyl-3,5-dimethyl-pyrazine, indole, hexanal, (Z)-jasmone, and (Z)-3-hexen-1-ol were the key contributors to the samples' aroma variation. Moreover, a quantitative descriptive analysis and aroma recombination and omission experiments analysis revealed that (E)-ß-ionone is the most critical contributor to the formation of floral aroma in tea processed using PCD, whereas (E,E)-2,4-heptadienal is responsible for the more pronounced fresh aroma in tea processed using HD. In addition, 2-ethyl-3,5-dimethyl-pyrazine contributes to the formation of a roasted aroma in tea processed using RD and RCD. The study results provide a theoretical basis for choosing the processing method, especially for drying, to obtain high-quality LAGP tea.
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Odorantes , Chá , Odorantes/análise , Chá/química , Pirazinas/análiseRESUMO
OBJECTIVE: To investigate the role of chemokine receptor ACKR2 in cognitive impairment in young rats with traumatic brain injury. METHODS: Seventy-five young rats were randomly divided into TBI group, TBI+Negative control (NC) group, TBI+Sensory integration (SI) group, TBI+Atypical chemokine receptor 2 (ACKR2) group and TBI+SI+ACKR2 group. We employed several techniques, including the water maze test, transmission electron microscope, HE staining, enzyme-linked immunosorbent assay, RT-PCR, western blotting to elucidate the role of ACKR2 in young rats with traumatic brain injury. RESULTS: We observed that the ability of learning and memory were significantly decreased, the serum inflammatory factors CCL2, IL-1ß and TNF-α were increased, the expression of Tau and NG2 was increased, and the expression of ACKR2 was decreased in TBI rats. After ACKR2 overexpression combined with SI, the learning ability and memory ability of TBI rats were improved, the levels of CCL2, IL-1ß, TNF-α were decreased, the expressions of Tau and NG2 were decreased, which were better than those of SI and ACKR2 groups. CONCLUSION: ACKR2 may be an effective method for improving the results after TBI in young rats.
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A simple and effective preconcentration method based on magnetic core-shell silica nanoparticles with C(18)-modified surface was developed for the analysis of pesticide residues in environmental water samples by gas chromatography-mass spectrometry. Several kinds of organophosphorous and pyrethroid pesticides including methamidophos, dichlorvos, orthene, phorate, dimethoate, carbofuran, bifenthrin, fenpropathrin, cypermethrin, fenvalerate, and deltamethrin were used as model compounds to systematically evaluate the method. Various parameters, including the amounts of magnetic nanoparticles absorbents, extraction time, eluting solvent, eluting volume, and sample pH values were optimized. The optimized method affords low detection limits (signal-to-noise ratio = 3) from 0.001 to 0.008 µg/L, and shows good linearity with correlation coefficients over 0.9990 in the concentration range of 0.025-0.5 µg/L. Average recoveries at three spiked levels were in the range of 70.2-110.2% with relative standard deviations below 9.6%. A maximum enrichment factor of 1015 times was achieved. Analysis results of poisoned pond water indicate that this method is fast, convenient, and efficient for the detections of low-concentration pesticides in aqueous samples.
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Nanopartículas de Magnetita/química , Nanopartículas/química , Praguicidas/análise , Dióxido de Silício/química , Extração em Fase Sólida , Poluentes Químicos da Água/química , Cromatografia Gasosa-Espectrometria de Massas , Compostos Organofosforados/análise , Piretrinas/análise , Propriedades de SuperfícieRESUMO
Cellulose fiber (CF) paper is a low-cost, sustainable, and flexible substrate, which has gained increasing interest recently. Before practical usage, the functionalization of the pristine CF paper is indispensable to meet requirements of specific applications. Different from conventional surface modification or physical mixing methods, we report in situ growth of ultralong hydroxyapatite nanowires (HAPNWs) with lengths larger than 10 µm on the CF paper. HAPNWs are radially aligned on the surface of CFs, creating a micro/nanoscale hierarchical structure. By means of the excellent ion exchange ability of HAP and the hierarchical structure, the functions of the CF paper can be easily customized. As a proof-of-concept, we demonstrate two kinds of functional CF paper: (1) the photoluminescent CF paper by doping Eu3+ and Tb3+ ions into the crystal lattice of HAPNWs and (2) the superhydrophobic CF paper by coating poly(dimethylsiloxane) on the HAPNW hierarchical structure, which can be applied for self-cleaning and oil/water separation. It is expected that an in situ growth of ultralong HAPNWs will provide an instructive guideline for designing a CF paper with specific functions.
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Vapor generation using solar energy is emerging as an efficient technology for wastewater purification and seawater desalination to relieve global water crisis. However, salt deposition on the evaporation surface seriously impairs the long-term steady water evaporation performance. Herein, the flexible salt-rejecting photothermal paper comprising reduced graphene oxide (rGO) and ultralong hydroxyapatite nanowires (HNs) has been developed for high-performance solar energy-driven water evaporation and stable desalination of seawater. The rGO/HN photothermal paper has advantages such as the hierarchical porous structure, interconnected channels, high mechanical strength, high efficiencies of solar light absorption and photothermal conversion, fast water transportation, and good heat insulation and salt-rejecting properties. Furthermore, the hydrophilicity and hydrophobicity of the rGO/HN photothermal paper can be adjusted by regulating the thermal treatment time. The water evaporation rate and energy efficiency of the hydrophilic rGO/HN photothermal paper are 1.48 kg m-2 h-1 and 89.2%, respectively, under 1 sun illumination (1 kW m-2). The hydrophobic rGO/HN photothermal paper shows a long-time stable water evaporation and salt-rejecting performance in the process of seawater desalination. The flexible salt-rejecting rGO/HN photothermal paper can produce clean water from wastewater and seawater with high rejection rates of organic dyes, metal ions, and salt ions, and it is promising for applications in water purification and seawater desalination.