Detalhe da pesquisa
1.
Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Int J Cancer
; 139(9): 2116-26, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27376928
2.
Pyk2 promotes tumor progression in multiple myeloma.
Blood
; 124(17): 2675-86, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25217697
3.
Genetic liability between COVID-19 and pre-eclampsia/eclampsia: a Mendelian randomization study.
Hypertens Pregnancy
; 42(1): 2285757, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017693
4.
FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer.
Target Oncol
; 18(2): 269-285, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826464
5.
Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned.
J Am Chem Soc
; 133(35): 14042-53, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21761891
6.
Analysis of nursing assessment terminology for neurological conditions and its cross-mapping with the International Classification of Functioning, Disability and Health (ICF): A multi-centre cross-sectional study.
Nurs Open
; 8(5): 2686-2695, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33760375
7.
Lactation and progression to type 2 diabetes in patients with gestational diabetes mellitus: A systematic review and meta-analysis of cohort studies.
J Diabetes Investig
; 9(6): 1360-1369, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29575786
8.
Inhibition of FAK kinase activity preferentially targets cancer stem cells.
Oncotarget
; 8(31): 51733-51747, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28881682
9.
PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells.
Cancer Res
; 75(2): 446-55, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25432176
10.
Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking.
Cancer Biol Ther
; 16(4): 589-601, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25729885
11.
Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.
Sci Transl Med
; 6(237): 237ra68, 2014 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848258
12.
Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group.
Chem Commun (Camb)
; 48(96): 11766-8, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23114612
13.
In vitro and in vivo anticancer activity of (+)-spongistatin 1.
Anticancer Res
; 31(9): 2773-9, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21868519
14.
Design, synthesis, and biological evaluation of EF- and ABEF- analogues of (+)-spongistatin 1.
Org Lett
; 12(8): 1792-5, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20297810
15.
Total synthesis of ipomoeassin F.
Org Lett
; 11(6): 1417-20, 2009 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19228042
16.
Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A.
Mol Cancer Ther
; 8(5): 1250-60, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19417157
17.
Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis.
J Biol Chem
; 279(51): 53015-22, 2004 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15471885