Detalhe da pesquisa
1.
A Pilot Study to Assess the Suitability of Riboflavin as A Surrogate Marker of Breast Cancer Resistance Protein (BCRP) in Healthy Participants.
J Pharmacol Exp Ther
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296646
2.
Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo.
Drug Metab Dispos
; 51(7): 851-861, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055191
3.
Macroscopic Spiral Patterns of Cholesteric Cellulose Nanocrystals Induced by Chiral Doping and Vortex Flowing.
Biomacromolecules
; 24(2): 640-651, 2023 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36689602
4.
Model-based analysis for the population pharmacokinetics of iberdomide and its major active metabolite in healthy subjects and patients with relapsed and refractory multiple myeloma.
Br J Clin Pharmacol
; 89(1): 316-329, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35981078
5.
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions.
Pharm Res
; 40(11): 2567-2584, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523014
6.
An open-label, phase 1, randomized, three treatments, three-period, crossover, relative bioavailability study of CC-292, a potent and orally available inhibitor of bruton tyrosine kinase.
J Clin Pharm Ther
; 47(8): 1186-1193, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35307850
7.
Evaluation of iberdomide and cytochrome p450 drug-drug interaction potential in vitro and in a phase 1 study in healthy subjects.
Eur J Clin Pharmacol
; 77(2): 223-231, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32965548
8.
3-Dimentional printing of polysaccharides for water-treatment: A review.
Int J Biol Macromol
; 265(Pt 2): 131117, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522684
9.
Relative bioavailability of fedratinib through various alternative oral administration methods in healthy adults.
Cancer Chemother Pharmacol
; 93(4): 307-317, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37955741
10.
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.
Blood
; 118(4): 1109-12, 2011 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536862
11.
Effects of varying amounts of different biochars on mercury methylation in paddy soils and methylmercury accumulation in rice (Oryza sativa L.).
Sci Total Environ
; 874: 162459, 2023 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871735
12.
A Phase 1, Multicenter, Open-Label Study to Evaluate the Pharmacokinetics of Iberdomide in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared with Healthy Subjects.
Clin Pharmacol
; 15: 9-19, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36880014
13.
Exposure-Response Analysis to Assess the Concentration-QTc Relationship of Iberdomide.
Clin Pharmacol Drug Dev
; 12(8): 819-825, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37079714
14.
White Collar 1 Modulates Oxidative Sensitivity and Virulence by Regulating the HOG1 Pathway in Fusarium asiaticum.
Microbiol Spectr
; 11(3): e0520622, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37195224
15.
Propionate poses antivirulence activity against Botrytis cinerea via regulating its metabolism, infection cushion development and overall pathogenic factors.
Food Chem
; 410: 135443, 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36680882
16.
2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline & Global Harmonization; Hybrid Assays; Oligonucleotides & ADC; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Mass Spectrometry, Chromatography and Sample Preparation, Novel Technologies, Novel Modalities, and Novel Challenges, ICH M10 BMV Guideline & Global Harmonization Part 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 15(16): 955-1016, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650500
17.
An Open Label, Phase 1, Randomized, Seven-treatment, Seven-period, Crossover Study to Assess the Relative Bioavailability, pH Effect, Food Effect, and Dose Proportionality of CC-292, a Potent and Orally Available Bruton's Tyrosine Kinase Inhibitor.
Eur J Drug Metab Pharmacokinet
; 47(4): 579-592, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35657581
18.
Effect of fluconazole on the pharmacokinetics of a single dose of fedratinib in healthy adults.
Cancer Chemother Pharmacol
; 90(4): 325-334, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001108
19.
Plasma stability-dependent circulation of acyl glucuronide metabolites in humans: how circulating metabolite profiles of muraglitazar and peliglitazar can lead to misleading risk assessment.
Drug Metab Dispos
; 39(1): 123-31, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20876787
20.
First-in-Human, Single- and Multiple-Ascending-Dose Studies in Healthy Subjects to Assess Pharmacokinetics, Pharmacodynamics, and Safety/Tolerability of Iberdomide, a Novel Cereblon E3 Ligase Modulator.
Clin Pharmacol Drug Dev
; 10(5): 471-485, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32969202