Detalhe da pesquisa
1.
Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.
Cell
; 180(6): 1228-1244.e24, 2020 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142649
2.
Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALS.
Proc Natl Acad Sci U S A
; 120(47): e2315347120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967220
3.
Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J Biol Chem
; 299(6): 104798, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156398
4.
Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction.
EMBO J
; 39(22): e104464, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959911
5.
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer's disease.
J Neuroinflammation
; 21(1): 55, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383481
6.
Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes.
Acta Neuropathol
; 147(1): 84, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750212
7.
Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.
Neurobiol Dis
; 179: 106031, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736924
8.
Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis.
FASEB J
; 35(7): e21688, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34143516
9.
Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice.
J Neurochem
; 145(1): 80-89, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29282717
10.
A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.
Biochim Biophys Acta Mol Basis Dis
; 1864(6 Pt A): 2119-2130, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29551730
11.
Proteasomal Dysfunction Induced By Diclofenac Engenders Apoptosis Through Mitochondrial Pathway.
J Cell Biochem
; 118(5): 1014-1027, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27487200
12.
Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life.
Proc Natl Acad Sci U S A
; 111(11): 4309-14, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591609
13.
Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model.
Neurobiol Dis
; 86: 16-28, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607786
14.
Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis.
J Biol Chem
; 289(2): 1192-202, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24280224
15.
Neuroinflammation in motor neuron disease.
Nagoya J Med Sci
; 77(4): 537-49, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663933
16.
Disulfide scrambling describes the oligomer formation of superoxide dismutase (SOD1) proteins in the familial form of amyotrophic lateral sclerosis.
J Biol Chem
; 288(7): 4970-80, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264618
17.
Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked mutant TDP-43 proteins.
J Biol Chem
; 288(5): 3641-54, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23235148
18.
Loss of TDP-43 causes age-dependent progressive motor neuron degeneration.
Brain
; 136(Pt 5): 1371-82, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23449777
19.
Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities.
FEBS Open Bio
; 14(2): 194-216, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37330425
20.
An open chat with Koji Yamanaka.
FEBS Open Bio
; 14(2): 162-164, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38217066