Detalhe da pesquisa
1.
Amyloid Pathology Impairs Experience-Dependent Inhibitory Synaptic Plasticity.
J Neurosci
; 44(5)2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050105
2.
New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
Brain
; 147(5): 1710-1725, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38146639
3.
Mitochondrial oxidative stress contributes to the pathological aggregation and accumulation of tau oligomers in Alzheimer's disease.
Hum Mol Genet
; 31(15): 2498-2507, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165721
4.
RAGE mediates Aß accumulation in a mouse model of Alzheimer's disease via modulation of ß- and γ-secretase activity.
Hum Mol Genet
; 27(6): 1002-1014, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29329433
5.
Anxiety and task performance changes in an aging mouse model.
Biochem Biophys Res Commun
; 514(1): 246-251, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31029428
6.
PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.
Brain
; 140(12): 3233-3251, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077793
7.
Increased neuronal PreP activity reduces Aß accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model.
Hum Mol Genet
; 24(18): 5198-210, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26123488
8.
NR2B-dependent cyclophilin D translocation suppresses the recovery of synaptic transmission after oxygen-glucose deprivation.
Biochim Biophys Acta
; 1852(10 Pt A): 2225-2234, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232180
9.
RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environment.
J Neurosci
; 34(26): 8749-60, 2014 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24966375
10.
Mitochondrial permeability transition pore is a potential drug target for neurodegeneration.
Biochim Biophys Acta
; 1842(8): 1267-72, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24055979
11.
Cyclophilin D deficiency rescues Aß-impaired PKA/CREB signaling and alleviates synaptic degeneration.
Biochim Biophys Acta
; 1842(12 Pt A): 2517-27, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23507145
12.
Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.
Biochim Biophys Acta
; 1842(2): 220-31, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24252614
13.
Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction.
Biochem Biophys Res Commun
; 468(4): 719-25, 2015 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26577411
14.
Overexpression of 17ß-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death.
BMC Cancer
; 15: 166, 2015 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25879199
15.
Structure based design, synthesis, pharmacophore modeling, virtual screening, and molecular docking studies for identification of novel cyclophilin D inhibitors.
J Chem Inf Model
; 54(3): 902-12, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24555519
16.
Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model.
Biochim Biophys Acta
; 1822(2): 286-92, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22015470
17.
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
Proc Natl Acad Sci U S A
; 107(43): 18670-5, 2010 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937894
18.
From a Cell's Viewpoint: Targeting Mitochondria in Alzheimer's disease.
Drug Discov Today Ther Strateg
; 10(2): e91-e98, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558270
19.
Amyloid pathology impairs experience-dependent inhibitory synaptic plasticity.
bioRxiv
; 2023 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205469
20.
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
J Neurosci
; 31(6): 2313-20, 2011 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21307267